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Open AccessJournal ArticleDOI

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study

Ting Shi, +138 more
- 02 Sep 2017 - 
- Vol. 390, Iss: 10098, pp 946-958
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TLDR
In this paper, the authors estimated the incidence and hospital admission rate of RSV-associated acute lower respiratory infection (RSV-ALRI) in children younger than 5 years stratified by age and World Bank income regions.
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This article is published in The Lancet.The article was published on 2017-09-02 and is currently open access. It has received 1470 citations till now. The article focuses on the topics: Disease burden & Case fatality rate.

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Rates of Medically Attended RSV Among US Adults: A Systematic Review and Meta-analysis

TL;DR: The true burden of RSV has been underestimated and is significant among older adults and individuals with chronic medical conditions, and a highly effective adult RSV vaccine would have substantial public health impact.
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Model-based estimates of transmission of respiratory syncytial virus within households

TL;DR: This analysis presents the first transmission modelling of cohort data for RSV and finds that it is important to consider the household social structuring and household size when modelling transmission.
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Revisiting respiratory syncytial virus’s interaction with host immunity, towards novel therapeutics

TL;DR: This review aims to discuss how the current knowledgebase could be used to combat this global viral threat and update and focus the research community's understanding of RSV’s interaction with immune defences.
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Determining the outcomes of interventions to prevent respiratory syncytial virus disease in children: what to measure?

TL;DR: Assessment of the prevalence and severity of recurrent wheezing or asthma in children aged up to 6 years and standardised assessments in diverse settings are needed to fully evaluate the effect of RSV preventive interventions.
References
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Meta-Analysis in Clinical Trials*

TL;DR: This paper examines eight published reviews each reporting results from several related trials in order to evaluate the efficacy of a certain treatment for a specified medical condition and suggests a simple noniterative procedure for characterizing the distribution of treatment effects in a series of studies.
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Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015

Haidong Wang, +844 more
- 08 Oct 2016 - 
TL;DR: The Global Burden of Disease 2015 Study provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015, finding several countries in sub-Saharan Africa had very large gains in life expectancy, rebounding from an era of exceedingly high loss of life due to HIV/AIDS.
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Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systematic analysis.

TL;DR: The authors' projection results provide concrete examples of how the distribution of child causes of deaths could look in 15-20 years to inform priority setting in the post-2015 era.
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