Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study

doi:10.1016/S0140-6736(17)30938-8

Open AccessJournal ArticleDOI

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study

Ting Shi, +138 more

- 02 Sep 2017 -

The Lancet

- Vol. 390, Iss: 10098, pp 946-958

Chats0

TLDR

In this paper, the authors estimated the incidence and hospital admission rate of RSV-associated acute lower respiratory infection (RSV-ALRI) in children younger than 5 years stratified by age and World Bank income regions.

About:

This article is published in The Lancet.The article was published on 2017-09-02 and is currently open access. It has received 1470 citations till now. The article focuses on the topics: Disease burden & Case fatality rate.

Citations

PDF

Open Access

More filters

Journal ArticleDOI

Effectiveness of palivizumab immunoprophylaxis to prevent respiratory syncytial virus hospitalizations in healthy full-term <6-month-old infants from the circumpolar region of Nunavik, Quebec, Canada.

Rodica Gilca, +7 more

- 21 Aug 2020 -

Preventive medicine reports

TL;DR: Over three RSV seasons, there was no evidence that PVZ reduced RSV hospitalizations in HFT Nunavik infants, and the sub-optimal adherence to the recommended PVZ administration schedule suggests feasibility and acceptability issues.

...read moreread less

Journal ArticleDOI

Lentiviral and AAV-mediated expression of palivizumab offer protection against Respiratory Syncytial Virus infection.

Agata Antepowicz, +5 more

- 03 Aug 2021 -

Scientific Reports

TL;DR: Gen delivery approaches via recombinant adeno-associated virus and simian immunodeficiency virus vectors are investigated to achieve sustained in vivo production of palivizumab in a murine model, allowing for wider use and reduction in treatment costs in vulnerable populations.

...read moreread less

Journal ArticleDOI

Long-Term Pulmonary Outcomes in Children Mechanically Ventilated for Severe Bronchiolitis*

Eleonore S.V. de Sonnaville, +5 more

- 29 Jul 2022 -

Pediatric Critical Care Medicine

TL;DR: In this single-center cohort, one-quarter of the children attending follow-up with a history of invasive mechanical ventilation for bronchiolitis had adverse, mostly previously undetected, long-term pulmonary outcomes at 6–12 years.

...read moreread less

Journal ArticleDOI

Recurrent Respiratory Syncytial Virus Infection in a CD14-Deficient Patient

Sjanna B. Besteman, +25 more

- 16 Apr 2022 -

The Journal of Infectious Diseases

TL;DR: An association of recurrent RSV bronchiolitis with a loss of CD14 function in immune cells is reported, which led to defective immune responses to RSV pre- and post-F protein without a change in viral replication.

...read moreread less

Journal ArticleDOI

Clinical Burden of Respiratory Syncytial Virus in Hospitalized Children Aged ≤5 Years (INSPIRE Study)

Katrin Hartmann, +8 more

- 13 Apr 2022 -

The Journal of Infectious Diseases

TL;DR: RSV causes substantial burden in hospitalized children (≤5 years), particularly preterm infants and those aged <6 months, particularly before and after hospitalization.

...read moreread less

Collapse

References

PDF

Open Access

More filters

Journal ArticleDOI

Meta-Analysis in Clinical Trials*

Rebecca DerSimonian, +3 more

- 01 Sep 1986 -

Controlled Clinical Trials

TL;DR: This paper examines eight published reviews each reporting results from several related trials in order to evaluate the efficacy of a certain treatment for a specified medical condition and suggests a simple noniterative procedure for characterizing the distribution of treatment effects in a series of studies.

...read moreread less

The Global Burden of Disease Study

Christopher J L Murray, +1 more

Journal ArticleDOI

Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015

Haidong Wang, +844 more

- 08 Oct 2016 -

The Lancet

TL;DR: The Global Burden of Disease 2015 Study provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015, finding several countries in sub-Saharan Africa had very large gains in life expectancy, rebounding from an era of exceedingly high loss of life due to HIV/AIDS.

...read moreread less

Journal ArticleDOI

Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systematic analysis.

Lei Liu, +8 more

- 31 Jan 2015 -

The Lancet

TL;DR: The authors' projection results provide concrete examples of how the distribution of child causes of deaths could look in 15-20 years to inform priority setting in the post-2015 era.

...read moreread less

Journal ArticleDOI

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

Harish Nair, +24 more

- 01 May 2010 -

The Lancet

TL;DR: Mortality data suggest that RSV is an important cause of death in childhood from ALRI, after pneumococcal pneumonia and Haemophilus influenzae type b, and the development of novel prevention and treatment strategies should be accelerated as a priority.

...read moreread less