G
George Davey-Smith
Researcher at University of Bristol
Publications - 90
Citations - 11937
George Davey-Smith is an academic researcher from University of Bristol. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 39, co-authored 87 publications receiving 10850 citations. Previous affiliations of George Davey-Smith include Medical Research Council & University of Lausanne.
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Journal ArticleDOI
Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement
Julian Little,Julian P T Higgins,John P. A. Ioannidis,John P. A. Ioannidis,David Moher,Erik von Elm,Erik von Elm,Muin J. Khoury,Barbara Cohen,George Davey-Smith,Jeremy M. Grimshaw,Paul Scheet,Marta Gwinn,Robin E. Williamson,Guangyong Zou,Guangyong Zou,Kim Hutchings,Candice Y. Johnson,Valerie Tait,Miriam Wiens,Jean Golding,Cornelia M. van Duijn,John R. McLaughlin,Andrew D. Paterson,George A. Wells,Isabel Fortier,Matthew L. Freedman,Maja Zecevic,Richard J. King,Claire Infante-Rivard,Alex Stewart,Nick Birkett +31 more
TL;DR: The STREGA recommendations do not prescribe or dictate how a genetic association study should be designed but seek to enhance the transparency of its reporting, regardless of choices made during design, conduct, or analysis.
Journal ArticleDOI
Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci
Richa Saxena,Richa Saxena,Clara C. Elbers,Clara C. Elbers,Yiran Guo,Inga Peter,Tom R. Gaunt,Jessica L. Mega,Matthew B. Lanktree,Archana Tare,Archana Tare,Berta Almoguera Castillo,Berta Almoguera Castillo,Yun Li,Toby Johnson,Marcel Bruinenberg,Diane Gilbert-Diamond,Ramakrishnan Rajagopalan,Benjamin F. Voight,Benjamin F. Voight,Ashok Balasubramanyam,John Barnard,Florianne Bauer,Jens Baumert,Tushar Bhangale,Bernhard O. Böhm,Peter S. Braund,Paul Burton,Hareesh R. Chandrupatla,Robert Clarke,Rhonda M. Cooper-DeHoff,Errol D. Crook,George Davey-Smith,Ian N. M. Day,Anthonius de Boer,Mark C.H. De Groot,Fotios Drenos,Jane F. Ferguson,Caroline S. Fox,Clement E. Furlong,Quince Gibson,Christian Gieger,Lisa A. Gilhuijs-Pederson,Joseph T. Glessner,Anuj Goel,Yan Gong,Struan F.A. Grant,Diederick E. Grobbee,Claire E. Hastie,Steve E. Humphries,Cecilia E. Kim,Mika Kivimäki,Marcus E. Kleber,Christa Meisinger,Meena Kumari,Taimour Y. Langaee,Debbie A Lawlor,Mingyao Li,Maximilian T. Lobmeyer,Anke-Hilse Maitland-van der Zee,Matthijs F.L. Meijs,Cliona Molony,David A. Morrow,Gurunathan Murugesan,Solomon K. Musani,Christopher P. Nelson,Stephen Newhouse,Jeffery R. O'Connell,Sandosh Padmanabhan,Jutta Palmen,Sanjey R. Patel,Carl J. Pepine,Mary Pettinger,Thomas S. Price,Suzanne Rafelt,Jane E. Ranchalis,Asif Rasheed,Elisabeth A. Rosenthal,Ingo Ruczinski,Sonia Shah,Haiqing Shen,Günther Silbernagel,Erin N. Smith,Annemieke W M Spijkerman,Alice Stanton,Michael W. Steffes,Barbara Thorand,Mieke D. Trip,Pim van der Harst,Daphne L. van der A,Erik P A Van Iperen,Jessica van Setten,Jana V. van Vliet-Ostaptchouk,Niek Verweij,Bruce H. R. Wolffenbuttel,Taylor Young,M. Hadi Zafarmand,Joseph M. Zmuda,Michael Boehnke,David Altshuler,David Altshuler,Mark I. McCarthy,W. H. Linda Kao,James S. Pankow,Thomas P. Cappola,Peter S. Sever,Neil R Poulter,Mark J. Caulfield,Anna F. Dominiczak,Denis C. Shields,Deepak L. Bhatt,Li Zhang,Sean P. Curtis,John Danesh,Juan P. Casas,Juan P. Casas,Yvonne T. van der Schouw,N. Charlotte Onland-Moret,Pieter A. Doevendans,Gerald W. Dorn,Martin Farrall,Garret A. FitzGerald,Anders Hamsten,Robert A. Hegele,Aroon D. Hingorani,Marten H. Hofker,Gordon S. Huggins,Thomas Illig,Gail P. Jarvik,Julie A. Johnson,Olaf H. Klungel,William C. Knowler,Wolfgang Koenig,Winfried März,James B. Meigs,Olle Melander,Patricia B. Munroe,Braxton D. Mitchell,S. J. Bielinski,Daniel J. Rader,Muredach P. Reilly,Stephen S. Rich,Jerome I. Rotter,Danish Saleheen,Nilesh J. Samani,Eric E. Schadt,Alan R. Shuldiner,Roy L. Silverstein,Kandice Kottke-Marchant,Philippa J. Talmud,Hugh Watkins,Folkert W. Asselbergs,Paul I.W. de Bakker,Paul I.W. de Bakker,Paul I.W. de Bakker,Jeanne M. McCaffery,Cisca Wijmenga,Marc S. Sabatine,James G. Wilson,Alexander P. Reiner,Donald W. Bowden,Hakon Hakonarson,David S. Siscovick,Brendan J. Keating +163 more
TL;DR: Large-scale meta-analysis involving a dense gene-centric approach has uncovered additional loci and variants that contribute to type 2 diabetes risk and suggests substantial overlap of T2D association signals across multiple ethnic groups.
Journal ArticleDOI
A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci
David A. Hinds,George McMahon,Amy K. Kiefer,Chuong B. Do,Nicholas Eriksson,David M. Evans,Beate St Pourcain,Susan M. Ring,Joanna L. Mountain,Uta Francke,George Davey-Smith,Nicholas J. Timpson,Joyce Y. Tung +12 more
TL;DR: A meta-analysis of genome-wide associations with self-reported cat, dust-mite and pollen allergies in 53,862 individuals used generalized estimating equations to model shared and allergy-specific genetic effects and sheds new light on the shared etiology of immune and autoimmune disease.
Journal ArticleDOI
Genome-wide analysis identifies 12 loci influencing human reproductive behavior
Nicola Barban,Rick Jansen,Ronald de Vlaming,Ahmad Vaez,Ahmad Vaez,Jornt J. Mandemakers,Felix C. Tropf,Xia Shen,Xia Shen,James F. Wilson,Daniel I. Chasman,Ilja M. Nolte,Vinicius Tragante,Sander W. van der Laan,John R. B. Perry,Augustine Kong,Augustine Kong,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Eva Albrecht,Laura M. Yerges-Armstrong,Gil Atzmon,Gil Atzmon,Kirsi Auro,Kirsi Auro,Kristin L. Ayers,Andrew Bakshi,Danny Ben-Avraham,Klaus Berger,Aviv Bergman,Lars Bertram,Lars Bertram,Lawrence F. Bielak,Gyda Bjornsdottir,Marc Jan Bonder,Linda Broer,Minh Bui,Caterina Barbieri,Alana Cavadino,Alana Cavadino,Jorge E. Chavarro,Constance Turman,Maria Pina Concas,Heather J. Cordell,Gail Davies,Peter Eibich,Nicholas Eriksson,Tõnu Esko,Joel Eriksson,Fahimeh Falahi,Janine F. Felix,Mark Alan Fontana,Lude Franke,Ilaria Gandin,Audrey J. Gaskins,Christian Gieger,Erica P. Gunderson,Xiuqing Guo,Caroline Hayward,Chunyan He,Edith Hofer,Hongyan Huang,Peter K. Joshi,Stavroula Kanoni,Robert Karlsson,Stefan Kiechl,Annette Kifley,Alexander Kluttig,Peter Kraft,Vasiliki Lagou,Vasiliki Lagou,Cecile Lecoeur,Jari Lahti,Ruifang Li-Gao,Penelope A. Lind,Tian Liu,Enes Makalic,Crysovalanto Mamasoula,Lindsay K. Matteson,Hamdi Mbarek,Patrick F. McArdle,George McMahon,S. Fleur W. Meddens,S. Fleur W. Meddens,Evelin Mihailov,Michael B. Miller,Stacey A. Missmer,Claire Monnereau,Peter J. van der Most,Ronny Myhre,Mike A. Nalls,Teresa Nutile,Ioanna P. Kalafati,Eleonora Porcu,Inga Prokopenko,Inga Prokopenko,Kumar B. Rajan,Janet W. Rich-Edwards,Cornelius A. Rietveld,Antonietta Robino,Lynda M. Rose,Rico Rueedi,Rico Rueedi,Kathleen A. Ryan,Yasaman Saba,Daniel F. Schmidt,Jennifer A. Smith,Lisette Stolk,Elizabeth A. Streeten,Anke Tönjes,Gudmar Thorleifsson,Sheila Ulivi,Juho Wedenoja,Juergen Wellmann,Peter Willeit,Jie Yao,Loic Yengo,Jing Hua Zhao,Wei Zhao,Daria V. Zhernakova,Najaf Amin,Howard Andrews,Beverley Balkau,Nir Barzilai,Sven Bergmann,Sven Bergmann,Ginevra Biino,Hans Bisgaard,Klaus Bønnelykke,Dorret I. Boomsma,Julie E. Buring,Harry Campbell,Stefania Cappellani,Marina Ciullo,Simon R. Cox,Francesco Cucca,Daniela Toniolo,George Davey-Smith,Ian J. Deary,George Dedoussis,Panos Deloukas,Panos Deloukas,Cornelia M. van Duijn,Eco J. C. de Geus,Johan G. Eriksson,Denis A. Evans,Jessica D. Faul,Cinzia Sala,Philippe Froguel,Paolo Gasparini,Giorgia Girotto,Hans J. Grabe,Karin Halina Greiser,Patrick J. F. Groenen,Hugoline G. de Haan,Johannes Haerting,Tamara B. Harris,Andrew C. Heath,Kauko Heikkilä,Albert Hofman,Albert Hofman,Georg Homuth,Elizabeth G. Holliday,John L. Hopper,Elina Hyppönen,Elina Hyppönen,Bo Jacobsson,Bo Jacobsson,Vincent W. V. Jaddoe,Magnus Johannesson,Astanand Jugessur,Mika Kähönen,Eero Kajantie,Eero Kajantie,Eero Kajantie,Sharon L.R. Kardia,Bernard Keavney,Bernard Keavney,Ivana Kolcic,P Koponen,Peter Kovacs,Florian Kronenberg,Zoltán Kutalik,Zoltán Kutalik,Martina La Bianca,Genevieve Lachance,William G. Iacono,Sandra Lai,Terho Lehtimäki,David C. Liewald,Cecilia M. Lindgren,Yongmei Liu,Robert Luben,Michael Lucht,Riitta Luoto,Per Magnus,Patrik K. E. Magnusson,Nicholas G. Martin,Matt McGue,Matt McGue,Ruth McQuillan,Sarah E. Medland,Christa Meisinger,Dan Mellström,Andres Metspalu,Andres Metspalu,Michela Traglia,Lili Milani,Paul Mitchell,Grant W. Montgomery,Grant W. Montgomery,Dennis O. Mook-Kanamori,Dennis O. Mook-Kanamori,Renée de Mutsert,Ellen A. Nohr,Claes Ohlsson,Jørn Olsen,Ken K. Ong,Lavinia Paternoster,Alison Pattie,Brenda W.J.H. Penninx,Markus Perola,Markus Perola,Markus Perola,Patricia A. Peyser,Mario Pirastu,Ozren Polasek,Chris Power,Jaakko Kaprio,Jaakko Kaprio,Leslie J. Raffel,Katri Räikkönen,Olli T. Raitakari,Paul M. Ridker,Susan M. Ring,Kathryn Roll,Igor Rudan,Daniela Ruggiero,Dan Rujescu,Veikko Salomaa,David Schlessinger,Helena Schmidt,Reinhold Schmidt,Nicole Schupf,Johannes W. A. Smit,Rossella Sorice,Tim D. Spector,John M. Starr,Doris Stöckl,Konstantin Strauch,Michael Stumvoll,Morris A. Swertz,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Roy Thurik,Nicholas J. Timpson,Joyce Y. Tung,André G. Uitterlinden,Simona Vaccargiu,J. Viikari,Veronique Vitart,Henry Völzke,Peter Vollenweider,Dragana Vuckovic,Johannes Waage,Gert G. Wagner,Jie Jin Wang,Nicholas J. Wareham,David R. Weir,Gonneke Willemsen,Johann Willeit,Alan F. Wright,Krina T. Zondervan,Kari Stefansson,Kari Stefansson,Robert F. Krueger,James J. Lee,Daniel J. Benjamin,Daniel J. Benjamin,David Cesarini,Philipp Koellinger,Philipp Koellinger,Marcel den Hoed,Harold Snieder,Melinda Mills +284 more
TL;DR: In this article, the authors reported a large genome-wide association study of both sexes including 251,151 individuals for AB and 343,072 individuals for NEB and identified 12 independent loci that are significantly associated with AB and NEB.
Journal ArticleDOI
Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis
David Wormser,Emanuele Di Angelantonio,Stephen Kaptoge,Angela M. Wood,Pei Gao,Qi Sun,Qi Sun,Göran Walldius,Randi Selmer,W. M. Monique Verschuren,H. Bas Bueno-de-Mesquita,Gunnar Engström,Paul M. Ridker,Inger Njølstad,Hiroyasu Iso,Ingar Holme,Simona Giampaoli,Hugh Tunstall-Pedoe,J. Michael Gaziano,Eric J. Brunner,Frank Kee,Alberto Tosetto,Christa Meisinger,Hermann Brenner,Pierre Ducimetière,Peter H. Whincup,Robert W. Tipping,Ian Ford,Peter Cremer,Albert Hofman,Lars Wilhelmsen,Robert Clarke,Ian H. de Boer,Ian H. de Boer,J. Wouter Jukema,J. Wouter Jukema,Alejandro Marín Ibañez,Debbie A Lawlor,Ralph B. D'Agostino,Beatriz L. Rodriguez,Edoardo Casiglia,Coen D.A. Stehouwer,Leon A. Simons,Paul J. Nietert,Elizabeth Barrett-Connor,Demosthenes B. Panagiotakos,Cecilia Björkelund,Timo Strandberg,Timo Strandberg,Sylvia Wassertheil-Smoller,Dan G. Blazer,Tom W. Meade,Lennart Welin,Kurt Svärdsudd,Mark Woodward,Aulikki Nissinen,Daan Kromhout,Torben Jørgensen,Reijo S. Tilvis,Reijo S. Tilvis,Jack M. Guralnik,Annika Rosengren,James O. Taylor,Stefan Kiechl,Gilles R. Dagenais,F. Gerry R. Fowkes,Robert B. Wallace,Kay-Tee Khaw,Jonathan A. Shaffer,Marjolein Visser,Jussi Kauhanen,Jukka T. Salonen,John Gallacher,John Gallacher,Yoav Ben-Shlomo,Yoav Ben-Shlomo,Akihiko Kitamura,Johan Sundström,Patrik Wennberg,Yutaka Kiyohara,Makoto Daimon,Agustín Gómez de la Cámara,Jackie A. Cooper,Altan Onat,Richard B. Devereux,Kenneth J. Mukamal,Kenneth J. Mukamal,Rachel Dankner,Matthew Knuiman,Carlos J. Crespo,Ron T. Gansevoort,Uri Goldbourt,Børge G. Nordestgaard,Jonathan E. Shaw,Michael E. Mussolino,Hidaeki Nakagawa,Astrid E. Fletcher,Lewis H. Kuller,Richard F. Gillum,Vilmundur Gudnason,Gerd Assmann,Nicholas J. Wald,P. Jousilahti,Philip Greenland,Maurizio Trevisan,Hanno Ulmer,Adam S. Butterworth,Aaron R. Folsom,George Davey-Smith,Frank B. Hu,John Danesh,Lara M. Simpson,Ingmar Jungner,Ellen W. Demerath,Nora Franceschini,Pamela L. Lutsey,Christos Pitsavos,Christina Chrysohoou,Christodoulos Stefanadis,Robert C. Atkins,Paul Zimmet,Elizabeth L M Barr,S. Goya Wannamethee,Richard W Morris,Johann Willeit,Siegfried Weger,Friedrich Oberhollenzer,Shah Ebrahim,John Yarnell,Valérie Tikhonoff,Christina M. Shay,Daniel B. Garside,Susan E. Sutherland,David Bachman,Julian E. Keil,Jorge R. Kizer,Bruce M. Psaty,Anne Tybjærg-Hansen,Gorm B. Jensen,Peter Schnohr,Luigi Palmieri,Salvatore Panico,Lorenza Pilotto,Diego Vanuzzo,Judith Simons,John McCallum,Yechiel Friedlander,Caroline L. Phillips,Frank J. Kohout,Joan Cornoni-Huntley,Nicholas J. Wareham,Ben Schöttker,Heiko Müller,Dietrich Rothenbacher,Jan-Håkan Jansson,Chiara Donfrancesco,Erkki Vartiainen,Kennet Harald,V V Salomaa,Ramachandran S. Vasan,Caroline S. Fox,Michael J. Pencina,Toshihide Oizumi,Takamasa Kayama,Takeo Kato,Else-Marie Bladbjerg,Lars Alling Møller,Jørgen Jespersen,Angela Chetrit,Flora Lubin,Henry Eriksson,Georgios Lappas,Calle Bengtsson,Lauren Lissner,Dorothea Nagel,Tatu A. Miettinen,Hisatomi Arima,Yasufumi Doi,Toshiharu Ninomiya,Jacqueline M. Dekker,Giel Nijpels,Eric B. Rimm,Walter C. Willett,Kazumasa Yamagishi,Hiroyuki Noda,Sudhir Kurl,Tomi-Pekka Tuomainen,Jan Poppelaars,Dorly J. H. Deeg,Bianca De Stavola,Bo Hedblad,Peter Nilsson,Anneke Blokstra,Steven J Shea,Barbara Thorand,Wolfgang Koenig,Angela Döring,Dorothea Nitsch,Greg Grandits,Aage Tverdal,Wenche Nystad,Joann E. Manson,Susan E. Hankinson,Kenneth A. Bauer,Karina W. Davidson,Susan Kirkland,Daichi Shimbo,Shinichi Sato,Katsuyuki Miura,Masaru Sakurai,Xavier Jouven,Stephan J. L. Bakker,Pim van der Harst,Hans L. Hillege,Mario R. Garcia-Palmieri,Philippe Amouyel,Dominique Arveiler,Jean Ferrières,Helmut Schulte,Anton J. M. de Craen,Naveed Sattar,David J. Stott,Bernard Cantin,Benoît Lamarche,Jean-Pierre Després,Jaclyn Bergstrom,Richele R. Bettencourt,Catherine Buisson,Thor Aspelund,Gunnar Sigurdsson,Bolli Thorsson,M. Arfan Ikram,Henning Tiemeier,Jacqueline C.M. Witteman,Roger Tavendale,Gordon D.O. Lowe,Jeun Liang Yeh,Tauqeer Ali,Darren Calhoun,Günay Can,Koshi Nakamura,Yuko Morikawa,Ellisiv B. Mathiesen,Maja-Lisa Løchen,Tom Wilsgaard,Erik Ingelsson,Karl Michaëlsson,Tommy Cederholm,Julie E. Buring,G. Diem,Hans Concin,Francesco Rodeghiero,Michael Marmot,Martin Shipley Mika Kivimaki,Michele Robertson,Edith J. M. Feskens,Johanna M. Geleijnse,Matthew G. Walker,Sarah Watson,Myriam Alexander,Oscar H. Franco,Reeta Gobin,Philip C Haycock,Sreenivasa Rao Kondapally Seshasai,Sarah Lewington,Lisa Pennells,Eleni Rapsomaniki,Nadeem Sarwar,Alexander M. W. Cargill Thompson,Simon G. Thompson,Ian R. White,Xiaohui Zhao +271 more
TL;DR: Adult height has directionally opposing relationships with risk of death from several different major causes of chronic diseases.