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Laura M. Raffield

Researcher at University of North Carolina at Chapel Hill

Publications -  179
Citations -  4816

Laura M. Raffield is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Genome-wide association study & Medicine. The author has an hindex of 23, co-authored 124 publications receiving 1948 citations. Previous affiliations of Laura M. Raffield include Medical University of South Carolina & Wake Forest University.

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Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data

Pierrick Wainschtein, +453 more
TL;DR: The results imply that rare variants, in particular those in regions of low linkage disequilibrium, are a major source of the still missing heritability of complex traits and disease.
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Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.

Seyedeh M. Zekavat, +355 more
TL;DR: In this article, the authors used deep-coverage whole genome sequencing in 8392 individuals of European and African ancestry to discover and interpret both single-nucleotide variants and copy number (CN) variation associated with Lp(a).
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Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

Nathalie Chami, +126 more
TL;DR: These rare, low-frequency, and common RBC variants showed pleiotropy, being also associated with platelet, white blood cell, and lipid traits, and suggest the involvement of new genes in human erythropoiesis.