Status of vaccine research and development for Shigella.

doi:10.1016/J.VACCINE.2016.02.075

Open AccessJournal ArticleDOI

Status of vaccine research and development for Shigella.

Sachin Mani, +2 more

- 03 Jun 2016 -

Vaccine

- Vol. 34, Iss: 26, pp 2887-2894

Chats0

TLDR

A landscape of Shigella vaccine development efforts is provided, including live attenuated, formalin-killed whole-cell, glycoconjugate, subunit, and novel antigen vaccines (e.g., Type III secretion system and outer membrane proteins).

About:

This article is published in Vaccine.The article was published on 2016-06-03 and is currently open access. It has received 176 citations till now. The article focuses on the topics: Shigella vaccine & Vaccine efficacy.

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Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990-2016.

Ibrahim A Khalil, +30 more

- 01 Nov 2018 -

Lancet Infectious Diseases

TL;DR: The global burden of shigella and ETEC diarrhoea according to age, sex, geography, and year from 1990 to 2016 is analyzed to assess the health burden of bacterial diarrhoeal pathogens globally.

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Use of quantitative molecular diagnostic methods to investigate the effect of enteropathogen infections on linear growth in children in low-resource settings: Longitudinal analysis of results from the MAL-ED cohort study

Elizabeth T. Rogawski, +157 more

- 01 Dec 2018 -

The Lancet Global Health

TL;DR: Subclinical infection and quantity of pathogens, particularly Shigella, enteroaggregative E coli, Campylobacter, and Giardia, had a substantial negative association with linear growth, which was sustained during the first 2 years of life, and in some cases, to 5 years.

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The role of vaccines in combatting antimicrobial resistance.

Francesca Micoli, +3 more

- 04 Feb 2021 -

Nature Reviews Microbiology

TL;DR: In this paper, the authors discuss evidence that vaccines can have a major role in fighting antimicrobial resistance (AMR), and describe the current state of development of vaccines against resistant bacterial pathogens that cause a substantial disease burden both in high-income countries and in low- and medium income countries, discuss possible obstacles that hinder progress in vaccine development and speculate on the impact of next-generation vaccines against bacterial infectious diseases on AMR.

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Potential targets for next generation antimicrobial glycoconjugate vaccines.

Francesca Micoli, +2 more

- 01 May 2018 -

Fems Microbiology Reviews

TL;DR: This review analyzes structural and functional differences of the polysaccharides exposed on the surface of emerging pathogenic bacteria, combined with medical need and technological feasibility of corresponding glycoconjugate vaccines.

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Journal ArticleDOI

Childhood diarrhoeal diseases in developing countries.

Harriet U. Ugboko, +3 more

- 01 Apr 2020 -

Heliyon

TL;DR: An overview of the recent trends in the epidemiology and treatment of diarrhoea is given and the potentials of metagenomics technique as a diagnostic method for enteric infections are highlighted.

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References

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Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Theo Vos, +363 more

- 15 Dec 2012 -

The Lancet

TL;DR: Prevalence and severity of health loss were weakly correlated and age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010, but population growth and ageing have increased YLD numbers and crude rates over the past two decades.

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Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010 (vol 380, pg 2197, 2012)

Christopher J L Murray, +4 more

- 01 Jan 2013 -

The Lancet

TL;DR: In this article, a comprehensive update of disease burden worldwide incorporating a systematic reassessment of disease and injury-specific epidemiology has been done since the 1990 study, and the authors aimed to calculate disease burden globally and for 21 regions for 1990, 2005, and 2010 with methods to enable meaningful comparisons over time.

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Journal ArticleDOI

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Christopher J L Murray, +369 more

- 15 Dec 2012 -

The Lancet

TL;DR: The results for 1990 and 2010 supersede all previously published Global Burden of Disease results and highlight the importance of understanding local burden of disease and setting goals and targets for the post-2015 agenda taking such patterns into account.

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Journal ArticleDOI

Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013

Mohsen Naghavi, +731 more

- 10 Jan 2015 -

The Lancet

TL;DR: In the Global Burden of Disease Study 2013 (GBD 2013) as discussed by the authors, the authors used the GBD 2010 methods with some refinements to improve accuracy applied to an updated database of vital registration, survey, and census data.

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Journal ArticleDOI

Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013

Theo Vos, +689 more

- 22 Aug 2015 -

The Lancet

TL;DR: In the Global Burden of Disease Study 2013 (GBD 2013) as mentioned in this paper, the authors estimated the quantities for acute and chronic diseases and injuries for 188 countries between 1990 and 2013.

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