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A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Stephen S Lim, +210 more
- 15 Dec 2012 - 
- Vol. 380, Iss: 9859, pp 2224-2260
TLDR
In this paper, the authors estimated deaths and disability-adjusted life years (DALYs; sum of years lived with disability [YLD] and years of life lost [YLL]) attributable to the independent effects of 67 risk factors and clusters of risk factors for 21 regions in 1990 and 2010.
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This article is published in The Lancet.The article was published on 2012-12-15 and is currently open access. It has received 9324 citations till now. The article focuses on the topics: Disease burden & Risk factor.

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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, +195 more
- 15 Dec 2012 - 
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.
Journal ArticleDOI

Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

Marie Ng, +141 more
- 30 Aug 2014 - 
TL;DR: The global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013 is estimated using a spatiotemporal Gaussian process regression model to estimate prevalence with 95% uncertainty intervals (UIs).
References
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Household and community poverty, biomass use, and air pollution in Accra, Ghana

TL;DR: Community biomass use had a stronger association with household PM than household's own fuel choice in crude and adjusted estimates, and Lack of regular physical access to clean fuels is an obstacle to fuel switching in low-income neighborhoods and should be addressed through equitable energy infrastructure.
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Cumulative exposure to arsenic and its relationship to respiratory cancer among copper smelter employees.

TL;DR: To explore the role of arsenic as a human carcinogen, the respiratory cancer mortality experience of 8,045 male smelter employees in Montana was examined relative to cumulative exposure to arsenic trioxide and was compared with that of the white male population of the same region.
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Bone lead levels and blood pressure endpoints: a meta-analysis.

TL;DR: Systolic blood pressure and hypertension risk were associated with lead levels in tibia bone, but the magnitude of the summary estimates was small and these summary estimates could not evaluate nonlinear dose–response relationships, the relative contribution of bone and blood lead levels, or the influence of differences in study populations.
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A review and meta-analysis of formaldehyde exposure and leukemia

TL;DR: Data do not provide consistent support for a relationship between formaldehyde exposure and leukemia risk and are evaluated to determine if publication or reporting biases may be affecting the estimates.
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Trends in coronary heart disease mortality and food consumption in the United States between 1909 and 1980.

TL;DR: Dietary substitutions towards less-saturated fatty acids support the hypothesized relationship between dietary fat and CHD and preceded CHD mortality changes by 10-20 y.
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Frequently Asked Questions (4)
Q1. What are the contributions mentioned in the paper "A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990—2010: a systematic analysis for the global burden of disease study 2010 author" ?

Lim, Stephen S, Vos, Umer, Shibuya, Shibaya, Kenji, AdairRohani, Heather, Amann, Markus, Anderson, H Ross, Andrews, Kathryn G, Aryee, Martin, Gmel, Gerhard, Graham, Kathryn, Grainger, Rebecca, Grant, Bridget, Gunnell, David, Gutierrez, Hialy R, Hall, Wayne, Hoek, Hans W, Hogan, Anne-Charlson, H Dean, this paper, Nolla, Nissim, Nelson, Paul K 

Shortcomings in the evidence may be any of the following: insufficient duration of trials (or studies); insufficient trials (or studies) available; inadequate sample sizes; or incomplete follow-up. 

The available evidence is based on a substantial number of studies including prospective observational studies and where relevant, randomised controlled trials of sufficient size, duration, and quality showing consistent effects. 

In reality, the burden attributable to different risks overlaps because of multicausality and because the effects of some risk factors are partly mediated throughLim et al.