University of Hawaii at Manoa

About: University of Hawaii at Manoa is a education organization based out in Honolulu, Hawaii, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 13693 authors who have published 25161 publications receiving 1023924 citations.

A method for the isolation and identification of dengue viruses, using mosquito cell cultures

Abstract: An improved method for the isolation and identification of dengue viruses is described. Viruses were isolated in mosquito cell cultures (C6/36 or AP-61), identified by indirect fluorescent antibody technique, and typed by complement-fixation test, using the cell culture fluid as antigen. The sensitivity of this method was compared with mosquito inoculation in comparative titrations of 16 low passage dengue virus strains. Although lower virus titers were obtained by the mosquito cell culture technique, its decreased sensitivity was compensated for by the much larger volume (588×) which could be assayed. By incubating the mosquito cells at 32°C, dengue viruses can be identified and typed within 6 days after inoculation.

A New Faint Milky Way Satellite Discovered in the Pan-STARRS1 3π Survey

Abstract: We present the discovery of a faint Milky Way satellite, Laevens 2/Triangulum II, found in the Panoramic Survey Telescope And Rapid Response System (Pan-STARRS 1) 3 pi imaging data and confirmed with follow-up wide-field photometry from the Large Binocular Cameras. The stellar system, with an absolute magnitude of M_V=-1.8 +/-0.5, a heliocentric distance of 30 +2/-2 kpc, and a half-mass radius of 34 +9/-8 pc, shows remarkable similarity to faint, nearby, small satellites such as Willman 1, Segue 1, Segue 2, and Bo\"otes II. The discovery of Laevens 2/Triangulum II further populates the region of parameter space for which the boundary between dwarf galaxies and globular clusters becomes tenuous. Follow-up spectroscopy will ultimately determine the nature of this new satellite, whose spatial location hints at a possible connection with the complex Triangulum-Andromeda stellar structures.

When Organizations Rule: Judicial Deference to Institutionalized Employment Structures

Abstract: This article offers a theoretical and empirical analysis of legal endogeneity—a powerful process through which institutionalized organizational structures influence judicial conceptions of compliance with antidiscrimination law. It finds that organizational structures (e.g., grievance and evaluation procedures, antiharassment policies) become symbolic indicators of rational governance and compliance with antidiscrimination laws, first within organizations, but eventually in the judicial realm as well. Lawyers and judges tend to infer nondiscrimination from the mere presence of those structures. Judges increasingly defer to organizational structures in their opinions, ultimately inferring nondiscrimination from their presence. Legal endogeneity theory is tested by analyzing a random sample of 1,024 federal employment discrimination opinions (1965–99) and is found to have increased over time. Judicial deference is most likely when plaintiffs lack clout and when the legal theories require judges to rule on u...

Lupus disks with faint CO isotopologues: low gas/dust or high carbon depletion?

Abstract: Context. An era has started in which gas and dust can be observed independently in protoplanetary disks, thanks to the recent surveys with the Atacama Large Millimeter/sub-millimeter Array (ALMA). The first near-complete high-resolution disk survey in both dust and gas in a single star-forming region has been carried out in Lupus, finding surprisingly low gas-to-dust ratios.Aims. The goal of this work is to fully exploit CO isotopologue observations in Lupus, comparing them with physical-chemical model results, in order to obtain gas masses for a large number of disks and compare gas and dust properties.Methods. We have employed the grid of physical-chemical models presented previously to analyze continuum and CO isotopologue (13 CO J = 3−2 and C18 O J = 3−2) observations of Lupus disks, including isotope-selective processes and freeze-out. We also employed the ALMA 13 CO-only detections to calculate disk gas masses for a total of 34 sources, which expands the sample of 10 disks reported earlier, where C18 O was also detected.Results. We confirm that overall gas-masses are very low, often lower than 1M J , when volatile carbon is not depleted. Accordingly, global gas-to-dust ratios are much lower than the expected interstellar-medium value of 100, which is predominantly between 1 and 10. Low CO-based gas masses and gas-to-dust ratios may indicate rapid loss of gas, or alternatively chemical evolution, for example, through sequestering of carbon from CO to more complex molecules, or carbon locked up in larger bodies.Conclusions. Current ALMA observations of 13 CO and continuum emission cannot distinguish between these two hypotheses. We have simulated both scenarios, but chemical model results do not allow us to rule out one of the two, pointing to the need to calibrate CO-based masses with other tracers. Assuming that all Lupus disks have evolved mainly as a result of viscous processes over the past few Myr, the previously observed correlation between the current mass accretion rate and dust mass implies a constant gas-to-dust ratio, which is close to 100 based on the observed M disk /Ṁ acc ratio. This in turn points to a scenario in which carbon depletion is responsible for the low luminosities of the CO isotopologue line.