R
Richard A. Flavell
Researcher at Yale University
Publications - 1389
Citations - 223064
Richard A. Flavell is an academic researcher from Yale University. The author has contributed to research in topics: Immune system & T cell. The author has an hindex of 231, co-authored 1328 publications receiving 205119 citations. Previous affiliations of Richard A. Flavell include National Institute for Medical Research & University of Michigan.
Papers
More filters
Journal ArticleDOI
Sequence homology of nuclear and mitochondrial DNAs of different yeasts.
TL;DR: The results suggest that the mitochondrial ribosomal cistrons have evolved more rapidly than the nuclear cists, and this is discussed in the light of theories on the rat of molecular evolutin.
Journal ArticleDOI
Costimulation in Tolerance and Autoimmunity
TL;DR: The evidence suggesting that the CD28-B7 costimulatory pathway might play an important role in T cell tolerance and in the development of autoimmune responses is reviewed.
Journal ArticleDOI
Excitatory transmission onto AgRP neurons is regulated by cJun NH2-terminal kinase 3 in response to metabolic stress.
Santiago Vernia,Caroline Morel,Joseph C. Madara,Joseph C. Madara,Julie Cavanagh-Kyros,Tamera Barrett,Kathryn Chase,Norman J. Kennedy,Dae Young Jung,Jason K. Kim,Neil Aronin,Richard A. Flavell,Bradford B. Lowell,Bradford B. Lowell,Roger J. Davis +14 more
TL;DR: It is demonstrated that JNK3 deficiency causes hyperphagia selectively in high fat diet (HFD)-fed mice and provides a mechanism that contributes to homeostatic regulation of energy balance in response to metabolic stress.
Journal ArticleDOI
Defective Th Function Induced by a Dominant-Negative cAMP Response Element Binding Protein Mutation Is Reversed by Bcl-2
TL;DR: CAMP response element binding protein plays a critical role in Th cell function and development of Th cell-mediated adaptive immune responses, at least in part, by inhibiting stimulus-dependent cell death.
Patent
Dna sequences, recombinant dna molecules and processes for producing soluble t4 proteins
Richard A. Fisher,Walter Gilbert,Vicki L. Sato,Richard A. Flavell,John M. Maraganore,Theresa R. Liu +5 more
TL;DR: In this paper, the authors proposed a method for producing soluble T4 protein, which can be used in immunotherapeutic and diagnostic compositions and methods for T4+ lymphocytes.