Universidade São Judas Tadeu

About: Universidade São Judas Tadeu is a education organization based out in São Paulo, Brazil. It is known for research contribution in the topics: Aerobic exercise & Baroreflex. The organization has 736 authors who have published 852 publications receiving 4782 citations.

Evaluation of Collagen Fibers, MMP2, MMP9, 8-OHdG and Apoptosis in the Aorta of Ovariectomized LDL Knockout Mice Submitted to Aerobic Exercise.

Abstract: Fundamento: Na menopausa, ha maior exposicao celular ao estresse oxidativo, relacionada a diminuicao dos efeitos antioxidantes do estrogenio. Essas alteracoes metabolicas favorecem a progressao das doencas cardiovasculares, como a aterosclerose. A funcao anormal da aorta – a arteria mais importante – esta associada a muitas doencas cardiovasculares. O colageno, especialmente os tipos I e III, e um dos mais importantes componentes da parede da aorta e pode ser afetado por muitos fatores, incluindo a menopausa. Por sua vez, 8-OHdG e [...]

Effects of Physical Training on the Myocardium of Oxariectomized LDLr Knockout Mice: MMP 2/9, Collagen I/III, Inflammation and Oxidative Stress

Abstract: Fundamento: O surgimento da doenca cardiaca coronariana aumenta com a menopausa, inatividade fisica e dislipidemia. Sabe-se que o treinamento fisico promove a melhora das funcoes cardiovasculares Objectivo: Investigar os efeitos do treinamento fisico aerobico sobre o ventriculo esquerdo em camundongos LDL knockout ovariectomizadas. Metodos: Trinta animais foram divididos em 6 grupos (n = 5): controle sedentario nao ovariectomizado, controle sedentario ovariectomizado, controle treinado ovariectomizado, sedentario LDL-knockout nao ovariectomizado, sedentario LDL-knockout ovariectomizado e treinado LDL-knockout ovariectomizado. Analisamos os parâmetros medios da [...]

Rapid Determination of the Thermal Nociceptive Threshold in Diabetic Rats

Abstract: Painful diabetic neuropathy (PDN) is characterized by hyperalgesia i.e., increased sensitivity to noxious stimulus, and allodynia i.e., hypersensitivity to normally innocuous stimuli. Hyperalgesia and allodynia have been studied in many different rodent models of diabetes mellitus. However, as stated by Bolcskei et al, determination of "pain" in animal models is challenging due to its subjective nature. Moreover, the traditional methods used to determine behavioral responses to noxious thermal stimuli usually lack reproducibility and pharmacological sensitivity. For instance, by using the hot-plate method of Ankier, flinch, withdrawal and/or licking of either hind- and/or fore-paws is quantified as reflex latencies at constant high thermal stimuli (52-55 °C). However, animals that are hyperalgesic to thermal stimulus do not reproducibly show differences in reflex latencies using those supra-threshold temperatures. As the recently described method of Bolcskei et al., the procedures described here allows for the rapid, sensitive and reproducible determination of thermal nociceptive thresholds (TNTs) in mice and rats. The method uses slowly increasing thermal stimulus applied mostly to the skin of mouse/rat plantar surface. The method is particularly sensitive to study anti-nociception during hyperalgesic states such as PDN. The procedures described bellow are based on the ones published in detail by Almasi et al and Bolcskei et al. The procedures described here have been approved the Laboratory Animal Care and Use Committee (LACUC), Wright State University.

Effects of a multicomponent exercise program on the functional fitness in elderly women

Abstract: Introduction: Aging is inevitable and irreversible, but with the advancement of technology, life expectancy is increasing every year, bringing proposals for various interventions to improve the quality of life. One such intervention is physical exercise programs. Objectives: To investigate the impact of multicomponent training in circuits on functional autonomy parameters in elderly women. Methods: Elderly were recruited and distributed in two groups: trained (N = 16) and non-trained (N = 15). Those in the trained group performed 75-minute training sessions twice a week over a 56-week period. The resistance training included upper and lower limbs with a relative intensity of 70% of 1RM, exercises using body weight, stretching and specific tasks for agility, performed in a circuit form and totaling three passages. Participants underwent functional autonomy (FA) assessment by the protocol of the Latin American Developmental Group for Maturity, the 6-minute walk test (T6M), and the sit-and-reach (SR) test. Results: The trained group had a significant decrease in body weight (p=0.02) and body mass index (p=0.015). Significant improvements (p=0,009) were also observed in FA, SR, and T6M after the intervention Compared with the untrained group, the trained group also obtained significant differences in all functional parameters analyzed. Conclusion: A long-term multicomponent training program conducted on a circuit and applied twice a week was enough to improve multiple components of the functional autonomy of elderly women. Level of Evidence II; Prognostic studies - Investigating the effect of a patient characteristic on the outcome of disease.

A BSP/CGM algorithm for finding all maximal contiguous subsequences of a sequence of numbers

Abstract: Given a sequence A of real numbers, we wish to find a list of all non-overlapping contiguous subsequences of A that are maximal. A maximal subsequence M of A has the property that no proper subsequence of M has a greater sum of values. Furthermore, M may not be contained properly within any subsequence of A with this property. This problem can be solved sequentially in linear time. We present a BSP/CGM algorithm that uses p processors and takes O (|A|/p) time and O (|A|/p) space per processor. The algorithm uses a constant number of communication rounds of size at most O (|A|/p). Thus the algorithm achieves linear speed-up and is highly scalable.