Showing papers by "Macquarie University published in 2012"

Global convergence in the vulnerability of forests to drought

Abstract: Shifts in rainfall patterns and increasing temperatures associated with climate change are likely to cause widespread forest decline in regions where droughts are predicted to increase in duration and severity(1). One primary cause of productivity loss and plant mortality during drought is hydraulic failure(2-4). Drought stress creates trapped gas emboli in the water transport system, which reduces the ability of plants to supply water to leaves for photosynthetic gas exchange and can ultimately result in desiccation and mortality. At present we lack a clear picture of how thresholds to hydraulic failure vary across a broad range of species and environments, despite many individual experiments. Here we draw together published and unpublished data on the vulnerability of the transport system to drought-induced embolism for a large number of woody species, with a view to examining the likely consequences of climate change for forest biomes. We show that 70% of 226 forest species from 81 sites worldwide operate with narrow (<1 megapascal) hydraulic safety margins against injurious levels of drought stress and therefore potentially face long-term reductions in productivity and survival if temperature and aridity increase as predicted for many regions across the globe(5,6). Safety margins are largely independent of mean annual precipitation, showing that there is global convergence in the vulnerability of forests to drought, with all forest biomes equally vulnerable to hydraulic failure regardless of their current rainfall environment. These findings provide insight into why drought-induced forest decline is occurring not only in arid regions but also in wet forests not normally considered at drought risk(7,8).

SMATR 3 - an R package for estimation and inference about allometric lines

Abstract: Summary 1. The Standardised Major Axis Tests and Routines (SMATR) software provides tools for estimation and inference about allometric lines, currently widely used in ecology and evolution. 2. This paper describes some significant improvements to the functionality of the package, now available on R in smatr version 3. 3. New inclusions in the package include sma and ma functions that accept formula input and perform the key inference tasks; multiple comparisons; graphical methods for visualising data and checking (S)MA assumptions; robust (S)MA estimation and inference tools.

CALIFA, the Calar Alto Legacy Integral Field Area survey : I. Survey presentation

Abstract: The final product of galaxy evolution through cosmic time is the population of galaxies in the local universe. These galaxies are also those that can be studied in most detail, thus providing a stringent benchmark for our understanding of galaxy evolution. Through the huge success of spectroscopic single-fiber, statistical surveys of the Local Universe in the last decade, it has become clear, however, that an authoritative observational description of galaxies will involve measuring their spatially resolved properties over their full optical extent for a statistically significant sample. We present here the Calar Alto Legacy Integral Field Area (CALIFA) survey, which has been designed to provide a first step in this direction. We summarize the survey goals and design, including sample selection and observational strategy. We also showcase the data taken during the first observing runs (June/July 2010) and outline the reduction pipeline, quality control schemes and general characteristics of the reduced data. This survey is obtaining spatially resolved spectroscopic information of a diameter selected sample of similar to 600 galaxies in the Local Universe (0.005 < z < 0.03). CALIFA has been designed to allow the building of two-dimensional maps of the following quantities: (a) stellar populations: ages and metallicities; (b) ionized gas: distribution, excitation mechanism and chemical abundances; and (c) kinematic properties: both from stellar and ionized gas components. CALIFA uses the PPAK integral field unit (IFU), with a hexagonal field-of-view of similar to 1.3 square', with a 100% covering factor by adopting a three-pointing dithering scheme. The optical wavelength range is covered from 3700 to 7000 angstrom, using two overlapping setups (V500 and V1200), with different resolutions: R similar to 850 and R similar to 1650, respectively. CALIFA is a legacy survey, intended for the community. The reduced data will be released, once the quality has been guaranteed. The analyzed data fulfill the expectations of the original observing proposal, on the basis of a set of quality checks and exploratory analysis: (i) the final datacubes reach a 3 sigma limiting surface brightness depth of similar to 23.0 mag/arcsec(2) for the V500 grating data (similar to 22.8 mag/arcsec(2) for V1200); (ii) about similar to 70% of the covered field-of-view is above this 3 sigma limit; (iii) the data have a blue-to-red relative flux calibration within a few percent in most of the wavelength range; (iv) the absolute flux calibration is accurate within similar to 8% with respect to SDSS; (v) the measured spectral resolution is similar to 85 km s(-1) for V1200 (similar to 150 km s(-1) for V500); (vi) the estimated accuracy of the wavelength calibration is similar to 5 km s(-1) for the V1200 data (similar to 10 km s(-1) for the V500 data); (vii) the aperture matched CALIFA and SDSS spectra are qualitatively and quantitatively similar. Finally, we show that we are able to carry out all measurements indicated above, recovering the properties of the stellar populations, the ionized gas and the kinematics of both components. The associated maps illustrate the spatial variation of these parameters across the field, reemphasizing the redshift dependence of single aperture spectroscopic measurements. We conclude from this first look at the data that CALIFA will be an important resource for archaeological studies of galaxies in the Local Universe.

Evaluation of climate models using palaeoclimatic data

Abstract: There is large uncertainty about the magnitude of warming and how rainfall patterns will change in response to any given scenario of future changes in atmospheric composition and land use. The models used for future climate projections were developed and calibrated using climate observations from the past 40 years. The geologic record of environmental responses to climate changes provides a unique opportunity to test model performance outside this limited climate range. Evaluation of model simulations against palaeodata shows that models reproduce the direction and large-scale patterns of past changes in climate, but tend to underestimate the magnitude of regional changes. As part of the effort to reduce model-related uncertainty and produce more reliable estimates of twenty-first century climate, the Palaeoclimate Modelling Intercomparison Project is systematically applying palaeoevaluation techniques to simulations of the past run with the models used to make future projections. This evaluation will provide assessments of model performance, including whether a model is sufficiently sensitive to changes in atmospheric composition, as well as providing estimates of the strength of biosphere and other feedbacks that could amplify the model response to these changes and modify the characteristics of climate variability.

The Sydney-AAO Multi-object Integral field spectrograph

Abstract: We demonstrate a novel technology that combines the power of the multi-object spectrograph with the spatial multiplex advantage of an integral field spectrograph (IFS). The SydneyAAO (Australian Astronomical Observatory) Multi-object IFS (SAMI) is a prototype widefield system at the Anglo-Australian Telescope (AAT) that allows 13 imaging fibre bundles (‘hexabundles’) to be deployed over a 1-degree diameter field of view. Each hexabundle comprises 61 lightly fused multi-mode fibres with reduced cladding and yields a 75 per cent filling factor. Each fibre core diameter subtends 1.6 arcsec on the sky and each hexabundle has a field of view of 15 arcsec diameter. The fibres are fed to the flexible AAOmega double-beam spectrograph, which can be used at a range of spectral resolutions (R = λ/δλ ≈ 1700–13 000) over the optical spectrum (3700–9500 A). We present the first spectroscopic results obtained with SAMI for a sample of galaxies at z ≈ 0.05. We discuss the prospects of implementing hexabundles at a much higher multiplex over wider fields of view in order to carry out spatially resolved spectroscopic surveys of 10 4 –10 5 galaxies.

Assessment of utility energy storage options for increased renewable energy penetration

Abstract: Renewable energy technologies are expected to take the leading role in the forthcoming energy generation portfolio in order to achieve sustainable energy generation. The major constraints for increasing penetration of renewable energy sources is their availability and intermittency, which can be addressed through energy storage when available and energy use when needed. This work reviews the energy storage technologies and gives an up to date comparative summary of the performance parameters of the major energy storage options. The parameters compared here include efficiency, energy capacity, energy density, run time, capital investment costs, response time, lifetime in years and cycles, self discharge and maturity of each energy storage option. The choice of storage system will depend on individual requirements, and may even incorporate more than one energy storage system to increase the energy storage capacity and improve energy security.

Reflections and projections: A decade of Intellectual Capital Accounting Research

Abstract: The purpose of this paper is to review and critique the field of Intellectual Capital Accounting Research (ICAR). The literature indicates that an organisational and business revolution is in progress concerning the need to understand the value of knowledge resources and how to manage them. The paper explores the field of ICAR by examining a decade of published research since Petty and Guthrie's (2000) seminal paper on ICA, “Intellectual capital literature review: Measurement, reporting and management” as published in the Journal of Intellectual Capital. The paper has four specific contributions. The first contribution is to identify the field of scholarship associated with ICAR. The second is to provide a comprehensive picture of what has happened in the field of ICAR over the past decade. Third, it provides evidence as to how and why the field of ICAR is changing. Fourth, it highlights areas for future research and policy developments. From these four contributions our definition of Intellectual Capital Accounting (ICA) emerges. That is, ICA is an accounting, reporting and management technology of relevance to organisations to understand and manage knowledge resources. It can account and report on the size and development of knowledge resources such as employee competencies, customer relations, financial relationships and communication and information technologies. Additionally, the analysis highlights several interesting patterns and worrying trends in the field of ICAR.

Comparative Genomics of Plant-Associated Pseudomonas spp.: Insights into Diversity and Inheritance of Traits Involved in Multitrophic Interactions

Abstract: We provide here a comparative genome analysis of ten strains within the Pseudomonas fluorescens group including seven new genomic sequences. These strains exhibit a diverse spectrum of traits involved in biological control and other multitrophic interactions with plants, microbes, and insects. Multilocus sequence analysis placed the strains in three sub-clades, which was reinforced by high levels of synteny, size of core genomes, and relatedness of orthologous genes between strains within a sub-clade. The heterogeneity of the P. fluorescens group was reflected in the large size of its pan-genome, which makes up approximately 54% of the pan-genome of the genus as a whole, and a core genome representing only 45–52% of the genome of any individual strain. We discovered genes for traits that were not known previously in the strains, including genes for the biosynthesis of the siderophores achromobactin and pseudomonine and the antibiotic 2-hexyl-5-propyl-alkylresorcinol; novel bacteriocins; type II, III, and VI secretion systems; and insect toxins. Certain gene clusters, such as those for two type III secretion systems, are present only in specific sub-clades, suggesting vertical inheritance. Almost all of the genes associated with multitrophic interactions map to genomic regions present in only a subset of the strains or unique to a specific strain. To explore the evolutionary origin of these genes, we mapped their distributions relative to the locations of mobile genetic elements and repetitive extragenic palindromic (REP) elements in each genome. The mobile genetic elements and many strain-specific genes fall into regions devoid of REP elements (i.e., REP deserts) and regions displaying atypical tri-nucleotide composition, possibly indicating relatively recent acquisition of these loci. Collectively, the results of this study highlight the enormous heterogeneity of the P. fluorescens group and the importance of the variable genome in tailoring individual strains to their specific lifestyles and functional repertoire.

The 6dF Galaxy Survey: z≈ 0 measurements of the growth rate and σ 8

Abstract: We present a detailed analysis of redshift-space distortions in the two-point correlation function of the 6dF Galaxy Survey (6dFGS). The K-band selected subsample which we employ in this study contains 81 971 galaxies distributed over 17 000 degree2 with an effective redshift zeff= 0.067. By modelling the 2D galaxy correlation function, , we measure the parameter combination f(zeff)σ8(zeff) = 0.423 ± 0.055, where is the growth rate of cosmic structure and σ8 is the rms of matter fluctuations in 8 h−1 Mpc spheres. Alternatively, by assuming standard gravity we can break the degeneracy between σ8 and the galaxy bias parameter b. Combining our data with the Hubble constant prior from Riess et al., we measure σ8= 0.76 ± 0.11 and Ωm= 0.250 ± 0.022, consistent with constraints from other galaxy surveys and the cosmic microwave background data from Wilkinson Microwave Anisotropy Probe 7 (WMAP7). Combining our measurement of fσ8 with WMAP7 allows us to test the cosmic growth history and the relationship between matter and gravity on cosmic scales by constraining the growth index of density fluctuations, γ. Using only 6dFGS and WMAP7 data we find γ= 0.547 ± 0.088, consistent with the prediction of General Relativity. We note that because of the low effective redshift of the 6dFGS our measurement of the growth rate is independent of the fiducial cosmological model (Alcock–Paczynski effect). We also show that our conclusions are not sensitive to the model adopted for non-linear redshift-space distortions. Using a Fisher matrix analysis we report predictions for constraints on fσ8 for the Wide-field Australian SKA Pathfinder telescope L-band Legacy All-sky Blind surveY (WALLABY) and the proposed Transforming Astronomical Imaging surveys through Polychromatic Analysis of Nebulae (TAIPAN) survey. The WALLABY survey will be able to measure fσ8 with a precision of 4–10 per cent, depending on the modelling of non-linear structure formation. This is comparable to the predicted precision for the best redshift bins of the Baryon Oscillation Spectroscopic Survey, demonstrating that low-redshift surveys have a significant role to play in future tests of dark energy and modified gravity.

The brain–gut pathway in functional gastrointestinal disorders is bidirectional: a 12-year prospective population-based study

Abstract: Objective Psychological factors are known to be associated with functional gastrointestinal disorders (FGIDs) including irritable bowel syndrome (IBS) and functional dyspepsia (FD). No prospective studies have evaluated whether it is the brain (eg, via anxiety) that drives gut symptoms, or whether gut dysfunction precipitates the central nervous system features such as anxiety. In a 12-year longitudinal, prospective, population-based study, we aimed to determine the directionality of the brain–gut mechanism in FGIDs. Design Participants (n=1775) were a random population sample from Australia who responded to a survey on FGIDs in 1997 and agreed to be contacted for future research; 1002 completed the 12-year follow-up survey (response rate =60%), with 217, 82 and 45 people meeting Rome II for new onset FGIDs, IBS and FD, respectively. Anxiety and depression were measured using the Delusions Symptom States Inventory at baseline and follow-up. Results Among people free of a FGID at baseline, higher levels of anxiety (OR 1.11; 95% CI 1.03 to 1.19, p=0.006) but not depression at baseline was a significant independent predictor of developing new onset FGIDs 12 years later. Among people who did not have elevated levels of anxiety and depression at baseline, those with a FGID at baseline had significantly higher levels of anxiety and depression at follow-up (mean difference coefficient 0.76, p Conclusions The central nervous system and gut interact bidirectionally in FGIDs.

Trichoderma reesei RUT-C30--thirty years of strain improvement.

Abstract: The hypersecreting mutant Trichoderma reesei RUT-C30 (ATCC 56765) is one of the most widely used strains of filamentous fungi for the production of cellulolytic enzymes and recombinant proteins, and for academic research. The strain was obtained after three rounds of random mutagenesis of the wild-type QM6a in a screening program focused on high cellulase production and catabolite derepression. Whereas RUT-C30 achieves outstanding levels of protein secretion and high cellulolytic activity in comparison to the wild-type QM6a, recombinant protein production has been less successful. Here, we bring together and discuss the results from biochemical-, microscopic-, genomic-, transcriptomic-, glycomic- and proteomic-based research on the RUT-C30 strain published over the last 30 years.

Vvv dr1: the first data release of the milky way bulge and southern plane from the near-infrared eso public survey vista variables in the via lactea

Abstract: Context The ESO public survey VISTA variables in the V�a L�ctea (VVV) started in 2010 VVV targets 562 sq deg in the Galactic bulge and an adjacent plane region and is expected to run for about five years Aims: We describe the progress of the survey observations in the first observing season, the observing strategy, and quality of the data obtained Methods: The observations are carried out on the 4-m VISTA telescope in the ZYJHK s filters In addition to the multi-band imaging the variability monitoring campaign in the K s filter has started Data reduction is carried out using the pipeline at the Cambridge Astronomical Survey Unit The photometric and astrometric calibration is performed via the numerous 2MASS sources observed in each pointing Results: The first data release contains the aperture photometry and astrometric catalogues for 348 individual pointings in the ZYJHK s filters taken in the 2010 observing season The typical image quality is 09 arcsec {-10 arcsec} The stringent photometric and image quality requirements of the survey are satisfied in 100% of the JHK s images in the disk area and 90% of the JHK s images in the bulge area The completeness in the Z and Y images is 84% in the disk, and 40% in the bulge The first season catalogues contain 128 � 10 8 stellar sources in the bulge and 168 � 10 8 in the disk area detected in at least one of the photometric bands The combined, multi-band catalogues contain more than 163 � 10 8 stellar sources About 10% of these are double detections because of overlapping adjacent pointings These overlapping multiple detections are used to characterise the quality of the data The images in the JHK s bands extend typically 4 mag deeper than 2MASS The magnitude limit and photometric quality depend strongly on crowding in the inner Galactic regions The astrometry for K s = 15-18 mag has rms 35-175 mas Conclusions: The VVV Survey data products offer a unique dataset to map the stellar populations in the Galactic bulge and the adjacent plane and provide an exciting new tool for the study of the structure, content, and star-formation history of our Galaxy, as well as for investigations of the newly discovered star clusters, star-forming regions in the disk, high proper motion stars, asteroids, planetary nebulae, and other interesting objects Based on observations taken within the ESO VISTA Public Survey VVV, Programme ID 179B-2002

Adult exposure influences offspring response to ocean acidification in oysters

Abstract: It is essential to predict the impact of elevated Pco2 on marine organisms and habitats to anticipate the severity and consequences of future ocean chemistry change. Despite the importance of carry-over effects in the evolutionary history of marine organisms, few studies have considered links between life-history stages when determining how marine organisms will respond to elevated Pco2, and none have considered the link between adults and their offspring. Herein, we exposed adults of wild and selectively bred Sydney rock oysters, Saccostrea glomerata to elevated Pco2 during reproductive conditioning and measured the development, growth and survival response of their larvae. We found that elevated Pco2 had a negative impact on larvae of S. glomerata causing a reduction in growth, rate of development and survival. Exposing adults to elevated Pco2 during reproductive conditioning, however, had positive carry-over effects on larvae. Larvae spawned from adults exposed to elevated Pco2 were larger and developed faster, but displayed similar survival compared with larvae spawned from adults exposed to ambient Pco2. Furthermore, selectively bred larvae of S. glomerata were more resilient to elevated Pco2 than wild larvae. Measurement of the standard metabolic rate (SMR) of adult S. glomerata showed that at ambient Pco2, SMR is increased in selectively bred compared with wild oysters and is further increased during exposure to elevated Pco2. This study suggests that sensitive marine organisms may have the capacity to acclimate or adapt to elevated Pco2 over the next century and a change in energy turnover indicated by SMR may be a key process involved.

Vulnerability of coastal communities to key impacts of climate change on coral reef fisheries.

Abstract: Coral reefs support the livelihood of millions of people especially those engaged in marine fisheries activities Coral reefs are highly vulnerable to climate change induced stresses that have led to substantial coral mortality over large spatial scales Such climate change impacts have the potential to lead to declines in marine fish production and compromise the livelihoods of fisheries dependent communities Yet few studies have examined social vulnerability in the context of changes specific to coral reef ecosystems In this paper, we examine three dimensions of vulnerability (exposure, sensitivity, and adaptive capacity) of 29 coastal communities across five western Indian Ocean countries to the impacts of coral bleaching on fishery returns A key contribution is the development of a novel, network-based approach to examining sensitivity to changes in the fishery that incorporates linkages between fishery and non-fishery occupations We find that key sources of vulnerability differ considerably within and between the five countries Our approach allows the visualization of how these dimensions of vulnerability differ from site to site, providing important insights into the types of nuanced policy interventions that may help to reduce vulnerability at a specific location To complement this, we develop framework of policy actions thought to reduce different aspects of vulnerability at varying spatial and temporal scales Although our results are specific to reef fisheries impacts from coral bleaching, this approach provides a framework for other types of threats and different social-ecological systems more broadly

Whole-genome sequence of Schistosoma haematobium

Abstract: Schistosomiasis is a neglected tropical disease caused by blood flukes (genus Schistosoma; schistosomes) and affecting 200 million people worldwide. No vaccines are available, and treatment relies on one drug, praziquantel. Schistosoma haematobium has come into the spotlight as a major cause of urogenital disease, as an agent linked to bladder cancer and as a predisposing factor for HIV/AIDS. The parasite is transmitted to humans from freshwater snails. Worms dwell in blood vessels and release eggs that become embedded in the bladder wall to elicit chronic immune-mediated disease and induce squamous cell carcinoma. Here we sequenced the 385-Mb genome of S. haematobium using Illumina-based technology at 74-fold coverage and compared it to sequences from related parasites. We included genome annotation based on function, gene ontology, networking and pathway mapping. This genome now provides an unprecedented resource for many fundamental research areas and shows great promise for the design of new disease interventions.

A 2D Quantum Walk Simulation of Two-Particle Dynamics

Abstract: Multidimensional quantum walks can exhibit highly nontrivial topological structure, providing a powerful tool for simulating quantum information and transport systems. We present a flexible implementation of a two-dimensional (2D) optical quantum walk on a lattice, demonstrating a scalable quantum walk on a nontrivial graph structure. We realized a coherent quantum walk over 12 steps and 169 positions by using an optical fiber network. With our broad spectrum of quantum coins, we were able to simulate the creation of entanglement in bipartite systems with conditioned interactions. Introducing dynamic control allowed for the investigation of effects such as strong nonlinearities or two-particle scattering. Our results illustrate the potential of quantum walks as a route for simulating and understanding complex quantum systems.

Toward interoperable bioscience data

Abstract: To make full use of research data, the bioscience community needs to adopt technologies and reward mechanisms that support interoperability and promote the growth of an open 'data commoning' culture. Here we describe the prerequisites for data commoning and present an established and growing ecosystem of solutions using the shared 'Investigation-Study-Assay' framework to support that vision.

Reconciling the temperature dependence of respiration across timescales and ecosystem types

Abstract: Ecosystem respiration is the biotic conversion of organic carbon to carbon dioxide by all of the organisms in an ecosystem, including both consumers and primary producers. Respiration exhibits an exponential temperature dependence at the subcellular and individual levels, but at the ecosystem level respiration can be modified by many variables including community abundance and biomass, which vary substantially among ecosystems. Despite its importance for predicting the responses of the biosphere to climate change, it is as yet unknown whether the temperature dependence of ecosystem respiration varies systematically between aquatic and terrestrial environments. Here we use the largest database of respiratory measurements yet compiled to show that the sensitivity of ecosystem respiration to seasonal changes in temperature is remarkably similar for diverse environments encompassing lakes, rivers, estuaries, the open ocean and forested and non-forested terrestrial ecosystems, with an average activation energy similar to that of the respiratory complex (approximately 0.65 electronvolts (eV)). By contrast, annual ecosystem respiration shows a substantially greater temperature dependence across aquatic (approximately 0.65 eV) versus terrestrial ecosystems (approximately 0.32 eV) that span broad geographic gradients in temperature. Using a model derived from metabolic theory, these findings can be reconciled by similarities in the biochemical kinetics of metabolism at the subcellular level, and fundamental differences in the importance of other variables besides temperature—such as primary productivity and allochthonous carbon inputs—on the structure of aquatic and terrestrial biota at the community level.

Predictability of biomass burning in response to climate changes

Abstract: Climate is an important control on biomass burning, but the sensitivity of fire to changes in temperature and moisture balance has not been quantified. We analyze sedimentary charcoal records to show that the changes in fire regime over the past 21,000 yrs are predictable from changes in regional climates. Analyses of paleo- fire data show that fire increases monotonically with changes in temperature and peaks at intermediate moisture levels, and that temperature is quantitatively the most important driver of changes in biomass burning over the past 21,000 yrs. Given that a similar relationship between climate drivers and fire emerges from analyses of the interannual variability in biomass burning shown by remote-sensing observations of month-by-month burnt area between 1996 and 2008, our results signal a serious cause for concern in the face of continuing global warming.

Structural analysis of N - and O -glycans released from glycoproteins

Abstract: This protocol shows how to obtain a detailed glycan compositional and structural profile from purified glycoproteins or protein mixtures, and it can be used to distinguish different isobaric glycan isomers. Glycoproteins are immobilized on PVDF membranes before the N-glycans are enzymatically released by PNGase F, isolated and reduced. Subsequently, O-glycans are chemically released from the same protein spot by reductive β-elimination. After desalting with cation exchange microcolumns, the glycans are separated and analyzed by porous graphitized carbon liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS). Optionally, the glycans can be treated with sialidases or other specific exoglycosidases to yield more detailed structural information. The sample preparation takes approximately 4 d, with a heavier workload on days 2 and 3, and a lighter load on days 1 and 4. The time for data interpretation depends on the complexity of the samples analyzed. This method can be used in conjunction with the analysis of enriched glycopeptides by capillary/nanoLC-ESI-MS/MS, which together provide detailed information regarding the site heterogeneity of glycosylation.

Intensity of dementia through latent variable modelling (I-DeLV) in the AIBL cohort

Abstract: 69% of Mild Cognitively Impaired and 96% of AD. Conclusions: The described models provide accurate estimations of NAB based on demographic corrected cognitive test scores. If NAB is a predictor for progression to AD and given such models can accurately predict NAB, it follows that this work may lead to an effective and economical screen for early detection of individuals at risk of developing AD, in-turn providing justification for further confirmatory tests (e.g. PET) or to identify suitable participants for intervention or therapeutic trials.

A framework for benchmarking land models

Abstract: Land models, which have been developed by the modeling community in the past few decades to predict fu- ture states of ecosystems and climate, have to be critically evaluated for their performance skills of simulating ecosys- tem responses and feedback to climate change. Benchmark- ing is an emerging procedure to measure performance of models against a set of defined standards. This paper pro- poses a benchmarking framework for evaluation of land model performances and, meanwhile, highlights major chal- lenges at this infant stage of benchmark analysis. The frame- work includes (1) targeted aspects of model performance

Prioritizing Key Resilience Indicators to Support Coral Reef Management in a Changing Climate

Abstract: Managing coral reefs for resilience to climate change is a popular concept but has been difficult to implement because the empirical scientific evidence has either not been evaluated or is sometimes unsupportive of theory, which leads to uncertainty when considering methods and identifying priority reefs. We asked experts and reviewed the scientific literature for guidance on the multiple physical and biological factors that affect the ability of coral reefs to resist and recover from climate disturbance. Eleven key factors to inform decisions based on scaling scientific evidence and the achievability of quantifying the factors were identified. Factors important to resistance and recovery, which are important components of resilience, were not strongly related, and should be assessed independently. The abundance of resistant (heat-tolerant) coral species and past temperature variability were perceived to provide the greatest resistance to climate change, while coral recruitment rates, and macroalgae abundance were most influential in the recovery process. Based on the 11 key factors, we tested an evidence-based framework for climate change resilience in an Indonesian marine protected area. The results suggest our evidence-weighted framework improved upon existing un-weighted methods in terms of characterizing resilience and distinguishing priority sites. The evaluation supports the concept that, despite high ecological complexity, relatively few strong variables can be important in influencing ecosystem dynamics. This is the first rigorous assessment of factors promoting coral reef resilience based on their perceived importance, empirical evidence, and feasibility of measurement. There were few differences between scientists' perceptions of factor importance and the scientific evidence found in journal publications but more before and after impact studies will be required to fully test the validity of all the factors. The methods here will increase the feasibility and defensibility of including key resilience metrics in evaluations of coral reefs, as well as reduce costs. Adaptation, marine protected areas, priority setting, resistance, recovery.

EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists

Abstract: The European Position Paper on Rhinosinusitis and Nasal Polyps 2012 is the update of similar evidence based position papers published in 2005 and 2007. The document contains chapters on definitions and classification, we now also proposed definitions for difficult to treat rhinosinusitis, control of disease and better definitions for rhinosinusitis in children. More emphasis is placed on the diagnosis and treatment of acute rhinosinusitis. Throughout the document the terms chronic rhinosinusitis without nasal polyps (CRSsNP) and chronic rhinosinusitis with nasal polyps (CRSwNP) are used to further point out differences in pathophysiology and treatment of these two entities. There are extensive chapters on epidemiology and predisposing factors, inflammatory mechanisms, (differential) diagnosis of facial pain, genetics, cystic fibrosis, aspirin exacerbated respiratory disease, immunodeficiencies, allergic fungal rhinosinusitis and the relationship between upper and lower airways. The chapters on paediatric acute and chronic rhinosinusitis are totally rewritten. Last but not least all available evidence for management of acute rhinosinusitis and chronic rhinosinusitis with or without nasal polyps in adults and children is analyzed and presented and management schemes based on the evidence are proposed. This executive summary for otorhinolaryngologists focuses on the most important changes and issues for otorhinolaryngologists. The full document can be downloaded for free on the website of this journal: http://www.rhinologyjournal.com.

The Characteristic Features of Auditory Verbal Hallucinations in Clinical and Nonclinical Groups: State-of-the-Art Overview and Future Directions

Abstract: Despite a growing interest in auditory verbal hallucinations (AVHs) in different clinical and nonclinical groups, the phenomenological characteristics of such experiences have not yet been reviewed and contrasted, limiting our understanding of these phenomena on multiple empirical, theoretical, and clinical levels. We look at some of the most prominent descriptive features of AVHs in schizophrenia (SZ). These are then examined in clinical conditions including substance abuse, Parkinson's disease, epilepsy, dementia, late-onset SZ, mood disorders, borderline personality disorder, hearing impairment, and dissociative disorders. The phenomenological changes linked to AVHs in prepsychotic stages are also outlined, together with a review of AVHs in healthy persons. A discussion of key issues and future research directions concludes the review.

Distributed leadership: a collaborative framework for academics, executives and professionals in higher education

Abstract: New models of leadership are needed for the higher education sector to continue to graduate students with leading edge capabilities. While multiple theories of leadership exist, the higher education sector requires a less hierarchical approach that takes account of its specialised and professional context. Over the last decade the sector has explored new leadership approaches based on public and private sector models accompanied by an increase in managerial control, market competition, government scrutiny and organisational restructuring. These changes have increased the gap between academics and ‘other’ staff as academic autonomy has been reduced. This paper presents a distributive leadership approach that places emphasis on collective collaboration rather than individual power and control. It describes a self-enabling tool developed from the experience of four Australian universities that used a distributed leadership approach to build leadership capacity in learning and teaching. The authors identify t...