Journal ArticleDOI
Cleft lip and palate
Reads0
Chats0
TLDR
Prevention is the ultimate objective for clefts of the lip and palate, and a prerequisite of this aim is to elucidate causes of the disorders.About:
This article is published in The Lancet.The article was published on 2009-11-21. It has received 1344 citations till now. The article focuses on the topics: Oral cleft & IRF6.read more
Citations
More filters
Journal ArticleDOI
Farsi version of the CLEFT-Q: translation, cultural adaptation process and reliability.
TL;DR: In this paper, the translation and cultural adaptation of the CLEFT-Q to Farsi and evaluating the reliability of it was performed. But the results showed that the internal consistency and stability were 0.979 and 0.997, respectively.
Journal ArticleDOI
Anesthetic Exposure in Staged Versus Single-Stage Cleft Lip and Palate Repair: Can we Reduce Risk of Anesthesia-Induced Developmental Neurotoxicity?
TL;DR: It is suggested that single-stage CLP repair can reduce wasted time under general anesthesia and potentially reduce harmful neuronal toxicity in the developmental period in this at-risk population.
Journal ArticleDOI
Presurgical Treatment of Cleft Lip and Palate Babies with a PNAM Appliance: A Series of Four Case Reports
TL;DR: The objectives of PNAM use in unilateral and bilateral cleft lip and palate patients are to presurgically decrease the severity of the cleft size, maintain a narrower cleft palate, and increase the length of the columella and height of the nostrils.
Journal ArticleDOI
The prevalence, risk of premature births, mortality and causes of death of cleft lip with or without palate in South Korea: a nationwide population-based cohort study.
TL;DR: CL/P children had high risks of premature births and risk of mortality, and the most common cause of deaths was cardiovascular anomalies in syndromic CL/P.
Journal ArticleDOI
Presurgical Cleft Management of Infants: A Survey of ACPA Approved and International Cleft Palate and Craniofacial Teams.
TL;DR: Most ACPA approved and ACPA registered international CP and craniofacial teams provided PSIO techniques by orthodontists using lip taping (LT) and AM, while few provide GPP.
References
More filters
Journal ArticleDOI
Retinoic Acid Embryopathy
TL;DR: It is possible that a major mechanism of isotretinoin teratogenesis is a deleterious effect on cephalic neural-crest cell activity that results in the observed craniofacial, cardiac, and thymic malformations.
Journal ArticleDOI
Women and smoking: a report of the Surgeon General.
Journal ArticleDOI
Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development.
TL;DR: It is suggested that Apaf1 is essential for Casp3 activation in embryonic brain and is a key regulator of developmental programmed cell death in mammals.
Journal ArticleDOI
Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome.
Virginia Kimonis,Alisa M. Goldstein,B. Pastakia,Mu Yang,Ronald G. Kase,John J. DiGiovanna,Allen E. Bale,Sherri J. Bale +7 more
TL;DR: The frequency of the clinical and radiological anomalies in Nevoid basal cell carcinoma syndrome in a large population of US patients is delineated and guidelines for diagnosis and management are discussed.
Journal ArticleDOI
Transforming growth factor-β3 is required for secondary palate fusion
Gabriele Proetzel,Sharon A. Pawlowski,Michael V. Wiles,Moying Yin,Gregory P. Boivin,Philip N. Howles,Jixang Ding,Mark W. J. Ferguson,Thomas Doetschman +8 more
TL;DR: This result demonstrates that TGF–β3 affects palatal shelf fusion by an intrinsic, primary mechanism rather than by effects secondary to craniofacial defects.
Related Papers (5)
A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4
Terri H. Beaty,Jeffrey C. Murray,Mary L. Marazita,Ronald G. Munger,Ingo Ruczinski,Jacqueline B. Hetmanski,Kung Yee Liang,Tao Wu,Tao Wu,Tanda Murray,M. Daniele Fallin,Richard A. Redett,Gerald V. Raymond,Holger Schwender,Sheng Chih Jin,Margaret E. Cooper,Martine Dunnwald,Maria A. Mansilla,Elizabeth J. Leslie,Stephen Bullard,Andrew C. Lidral,Lina M. Moreno,Renato Menezes,Alexandre R. Vieira,Aline Petrin,Allen J. Wilcox,Rolv T. Lie,Ethylin Wang Jabs,Ethylin Wang Jabs,Yah Huei Wu-Chou,Philip Kuo Ting Chen,Hong Wang,Xiaoqian Ye,Xiaoqian Ye,Shangzhi Huang,Vincent Yeow,Samuel S. Chong,Sun Ha Jee,Bing Shi,Kaare Christensen,Mads Melbye,Kimberly F. Doheny,Elizabeth W. Pugh,Hua Ling,Eduardo E. Castilla,Andrew E. Czeizel,Lian Ma,L. Leigh Field,Lawrence C. Brody,Faith Pangilinan,James L. Mills,Anne M. Molloy,Peadar N. Kirke,James M. Scott,Mauricio Arcos-Burgos,Alan F. Scott +55 more
Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24
Stefanie Birnbaum,Stefanie Birnbaum,Kerstin U. Ludwig,Heiko Reutter,Stefan Herms,Michael Steffens,Michele Rubini,Carlotta Baluardo,Melissa Ferrian,Nilma Almeida de Assis,Margrieta A. Alblas,Sandra Barth,Jan Freudenberg,Carola Lauster,Gül Schmidt,Martin Scheer,Bert Braumann,Stefaan J. Bergé,Rudolf H. Reich,Franziska Schiefke,Alexander Hemprich,Simone Pötzsch,Régine P.M. Steegers-Theunissen,Bernd Pötzsch,Susanne Moebus,Bernhard Horsthemke,Franz-Josef Kramer,Thomas F. Wienker,Peter A. Mossey,Peter Propping,Sven Cichon,Per Hoffmann,Michael Knapp,Markus M. Nöthen,Elisabeth Mangold +34 more
Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate
Elisabeth Mangold,Kerstin U. Ludwig,Stefanie Birnbaum,Carlotta Baluardo,Melissa Ferrian,Stefan Herms,Heiko Reutter,Nilma Almeida de Assis,Taofik Al Chawa,Manuel Mattheisen,Michael Steffens,Sandra Barth,Nadine Kluck,Anna Paul,Jessica Becker,Carola Lauster,Gül Schmidt,Bert Braumann,Martin Scheer,Rudolf H. Reich,Alexander Hemprich,Simone Pötzsch,Bettina Blaumeiser,Susanne Moebus,Michael Krawczak,Stefan Schreiber,Thomas Meitinger,Hans Erich Wichmann,Régine P.M. Steegers-Theunissen,Franz Josef Kramer,Sven Cichon,Peter Propping,Thomas F. Wienker,Michael Knapp,Michele Rubini,Peter A. Mossey,Per Hoffmann,Markus M. Nöthen +37 more