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Journal ArticleDOI

Cleft lip and palate

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TLDR
Prevention is the ultimate objective for clefts of the lip and palate, and a prerequisite of this aim is to elucidate causes of the disorders.
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This article is published in The Lancet.The article was published on 2009-11-21. It has received 1344 citations till now. The article focuses on the topics: Oral cleft & IRF6.

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Citations
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Dental and oral anomalies in incontinentia pigmenti: a systematic review

TL;DR: According to the frequency, dental and/or oral anomalies represent the most frequent and important IP minor criteria and the presence of cleft palate and high arched palate may be considered as diagnostic IPMinor criteria as well.
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Living with cleft lip and palate: the treatment journey.

TL;DR: In this article, a qualitative in-depth semistructured interviews with 11 adults with nonsyndromal complete cleft lip and palate (CLP) were conducted to understand how individuals with CLP perceive and experience their treatment process and how these perceptions and experiences change over the life course.
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Reporting characteristics of meta-analyses in orthodontics: methodological assessment and statistical recommendations

TL;DR: Evaluating the statistical methods, the methodology, and the quality characteristics of orthodontic MAs and to assess their reporting quality during the last years found specific characteristics like explicit protocol definition, extensive searches, and quality assessment of included trials were associated with a higher AMSTAR score.
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Three-dimensional assessment of pharyngeal airway in nasal- and mouth-breathing children

TL;DR: The CBCT evaluation showed that pharyngeal airway dimensions were significantly greater in nasal-b breathehers than in mouth-breathers.
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Cleft palate: A clinical review

TL;DR: A multidisciplinary team is necessary for the long-term pre- and postoperative care of CP patients to handle complications, associated anomalies, and to optimize function and quality of life.
References
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Journal ArticleDOI

Retinoic Acid Embryopathy

TL;DR: It is possible that a major mechanism of isotretinoin teratogenesis is a deleterious effect on cephalic neural-crest cell activity that results in the observed craniofacial, cardiac, and thymic malformations.
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Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development.

TL;DR: It is suggested that Apaf1 is essential for Casp3 activation in embryonic brain and is a key regulator of developmental programmed cell death in mammals.
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Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome.

TL;DR: The frequency of the clinical and radiological anomalies in Nevoid basal cell carcinoma syndrome in a large population of US patients is delineated and guidelines for diagnosis and management are discussed.
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Transforming growth factor-β3 is required for secondary palate fusion

TL;DR: This result demonstrates that TGF–β3 affects palatal shelf fusion by an intrinsic, primary mechanism rather than by effects secondary to craniofacial defects.
Related Papers (5)

A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4