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Journal ArticleDOI

Cleft lip and palate

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TLDR
Prevention is the ultimate objective for clefts of the lip and palate, and a prerequisite of this aim is to elucidate causes of the disorders.
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This article is published in The Lancet.The article was published on 2009-11-21. It has received 1344 citations till now. The article focuses on the topics: Oral cleft & IRF6.

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Citations
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Journal ArticleDOI

Cleft-Palate Repair: Does Hospital Case-Volume Impact Outcomes or Cost?

TL;DR: In institutions performing a high volume of cleft palate repairs, subjects had significantly decreased odds of experiencing a complication, prolonged length of stay, and increased total cost.
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Validation of the Dutch registry of common oral clefts: Quality of recording specific oral cleft features

TL;DR: Overall, the validity of Dutch registry data on oral cleft data is good, supporting the feasibility of this unique descriptive recording system, and the quality appears to be related to anatomical location and morphological severity.
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An Overview of Timeline of Interventions in the Continuum of Cleft Lip and Palate Care

TL;DR: An overview of timeline of interventions and the critical role different providers have in the continuum of cleft lip and palate care is provided.
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The prenatal diagnosis and classification of cleft palate: the role and value of magnetic resonance imaging

TL;DR: MRI could be a useful adjunct to US examination in the prenatal diagnosis of fetuses with cleft palate, and the accurate classification of CP diagnosed by MRI can guide clinical management.
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A Retrospective Study Identifying Breast Milk Feeding Disparities in Infants with Cleft Palate

TL;DR: Frequency of breast milk feeding at the breast and per feeder in infants with cleft palate was determined and compared with rates reported by the Centers for Disease Control and Prevention, and median weight-for-age and weight- for-length z scores suggest that growth of infants with CleFT palate was below normative standards.
References
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Journal ArticleDOI

Retinoic Acid Embryopathy

TL;DR: It is possible that a major mechanism of isotretinoin teratogenesis is a deleterious effect on cephalic neural-crest cell activity that results in the observed craniofacial, cardiac, and thymic malformations.
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Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development.

TL;DR: It is suggested that Apaf1 is essential for Casp3 activation in embryonic brain and is a key regulator of developmental programmed cell death in mammals.
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Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome.

TL;DR: The frequency of the clinical and radiological anomalies in Nevoid basal cell carcinoma syndrome in a large population of US patients is delineated and guidelines for diagnosis and management are discussed.
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Transforming growth factor-β3 is required for secondary palate fusion

TL;DR: This result demonstrates that TGF–β3 affects palatal shelf fusion by an intrinsic, primary mechanism rather than by effects secondary to craniofacial defects.
Related Papers (5)

A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4