Journal ArticleDOI
Cleft lip and palate
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TLDR
Prevention is the ultimate objective for clefts of the lip and palate, and a prerequisite of this aim is to elucidate causes of the disorders.About:
This article is published in The Lancet.The article was published on 2009-11-21. It has received 1344 citations till now. The article focuses on the topics: Oral cleft & IRF6.read more
Citations
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Book ChapterDOI
Robotic Cleft Palate Surgery and Simulation
Dale J. Podolsky,David M. Fisher,Karen W. Y. Wong Riff,Thomas Looi,James M. Drake,Christopher R. Forrest +5 more
TL;DR: A highly realistic cleft palate simulator was developed for testing existing and newly developed robotic systems to determine feasibility and efficacy of robotic CLEFT palate surgery as discussed by the authors, which has been validated as a realistic simulation environment and an effective and valuable training tool.
DissertationDOI
Utilizing high-throughput genomics methodologies to explore transcriptomes and exomes
TL;DR: This work utilized different high-throughput genomics methodologies to explore the exomes of human patients as well as transcriptomes of Drosophila melanogaster and Daphnia pulex, and provided us the methods and solutions to the research fields of genomes, transcriptomes and proteomics.
Journal ArticleDOI
Orofacial Dysfunction In Cleft And Non-Cleft Patients Using Nordic Orofacial Test - A Screening Study
Natalia Cristina Reinaldo Mariano,M. N. Sano,Karin Hermana Neppelenbroek,Ana Lúcia Pompéia Fraga de Almeida,Thais Marchini de Oliveira,Simone Soares +5 more
TL;DR: Individuals with CLAP showed more orofacial dysfunction than non-cleft patients, without gender differences, after being assessed through the NOT-S.
Indian nurses’ experiences of supporting parents of children with cleft lip and palate: A minor field study
Julia Hjalmarsson,Karin Kjernald +1 more
TL;DR: The findings show that the relationship to the parents was crucial for the nurses’ supporting actions to succeed, and some aspects of the Nurses’ work with supporting the parents are applicable to nurses' work with next of kin anywhere in the world.
References
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Journal ArticleDOI
Retinoic Acid Embryopathy
TL;DR: It is possible that a major mechanism of isotretinoin teratogenesis is a deleterious effect on cephalic neural-crest cell activity that results in the observed craniofacial, cardiac, and thymic malformations.
Journal ArticleDOI
Women and smoking: a report of the Surgeon General.
Journal ArticleDOI
Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development.
TL;DR: It is suggested that Apaf1 is essential for Casp3 activation in embryonic brain and is a key regulator of developmental programmed cell death in mammals.
Journal ArticleDOI
Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome.
Virginia Kimonis,Alisa M. Goldstein,B. Pastakia,Mu Yang,Ronald G. Kase,John J. DiGiovanna,Allen E. Bale,Sherri J. Bale +7 more
TL;DR: The frequency of the clinical and radiological anomalies in Nevoid basal cell carcinoma syndrome in a large population of US patients is delineated and guidelines for diagnosis and management are discussed.
Journal ArticleDOI
Transforming growth factor-β3 is required for secondary palate fusion
Gabriele Proetzel,Sharon A. Pawlowski,Michael V. Wiles,Moying Yin,Gregory P. Boivin,Philip N. Howles,Jixang Ding,Mark W. J. Ferguson,Thomas Doetschman +8 more
TL;DR: This result demonstrates that TGF–β3 affects palatal shelf fusion by an intrinsic, primary mechanism rather than by effects secondary to craniofacial defects.
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