Journal ArticleDOI
Cleft lip and palate
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TLDR
Prevention is the ultimate objective for clefts of the lip and palate, and a prerequisite of this aim is to elucidate causes of the disorders.About:
This article is published in The Lancet.The article was published on 2009-11-21. It has received 1344 citations till now. The article focuses on the topics: Oral cleft & IRF6.read more
Citations
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Higher concentration of selenium in placental tissues is associated with reduced risk for orofacial clefts.
TL;DR: The concentration of Se in placental tissues was dose-dependently associated with decreased risk for OFCs in offspring, and this finding suggests that maternal Se intake during pregnancy may protect against OFC in offspring.
Journal ArticleDOI
Cleft lip and palate in Madagascar 1998–2007
Richard Aurélien Rakotoarison,Andrianony Emmanuel Rakotoarivony,Norotiana Rabesandratana,John Bam Razafindrabe,Raoelina Andriambololona,Rabetrano Andriambololo-Nivo,Ahmed Feki +6 more
TL;DR: There was a high prevalence of oral clefts in general and associated or syndromic forms, or both, in the Vakinankaratra region and there may be a link between background high doses of ionising radiation in some areas because of the presence of former uranium mines.
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Airway management: A comparative study in cleft lip and palate repair surgery in children
Jayashree Sen,Bitan Sen +1 more
TL;DR: A comparative study in children using the endotracheal tubes available in the Institute found the RAE tube to be the choicest one and at a minimal risk for maintaining patients’ patent airway and other related complications.
Journal ArticleDOI
Maternal periconceptional consumption of sprouted potato and risks of neural tube defects and orofacial clefts
TL;DR: Maternal consumption of sprouted potatoes during periconceptional period may increase the risks of NTDs and OFCs and improper preservation and use should be a matter of concern in respect of the potential teratogenicity.
References
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Journal ArticleDOI
Retinoic Acid Embryopathy
TL;DR: It is possible that a major mechanism of isotretinoin teratogenesis is a deleterious effect on cephalic neural-crest cell activity that results in the observed craniofacial, cardiac, and thymic malformations.
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Women and smoking: a report of the Surgeon General.
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Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development.
TL;DR: It is suggested that Apaf1 is essential for Casp3 activation in embryonic brain and is a key regulator of developmental programmed cell death in mammals.
Journal ArticleDOI
Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome.
Virginia Kimonis,Alisa M. Goldstein,B. Pastakia,Mu Yang,Ronald G. Kase,John J. DiGiovanna,Allen E. Bale,Sherri J. Bale +7 more
TL;DR: The frequency of the clinical and radiological anomalies in Nevoid basal cell carcinoma syndrome in a large population of US patients is delineated and guidelines for diagnosis and management are discussed.
Journal ArticleDOI
Transforming growth factor-β3 is required for secondary palate fusion
Gabriele Proetzel,Sharon A. Pawlowski,Michael V. Wiles,Moying Yin,Gregory P. Boivin,Philip N. Howles,Jixang Ding,Mark W. J. Ferguson,Thomas Doetschman +8 more
TL;DR: This result demonstrates that TGF–β3 affects palatal shelf fusion by an intrinsic, primary mechanism rather than by effects secondary to craniofacial defects.
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