Journal ArticleDOI
Cleft lip and palate
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TLDR
Prevention is the ultimate objective for clefts of the lip and palate, and a prerequisite of this aim is to elucidate causes of the disorders.About:
This article is published in The Lancet.The article was published on 2009-11-21. It has received 1344 citations till now. The article focuses on the topics: Oral cleft & IRF6.read more
Citations
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Lower Respiratory Tract Infections and Orofacial Clefts: A Prospective Cohort Study From the Japan Environment and Children’s Study
TL;DR: In this article , the authors examined whether infants with orofacial clefts were associated with lower respiratory tract infections (LRTIs) and found that cleft infants were more likely to develop LRTIs.
Dissertation
Determining the role of GABAergic signaling in the craniofacial development of larval zebrafish
TL;DR: This paper aims to demonstrate the efforts towards in-situ applicability of EMMARM, as to provide real-time information about concrete mechanical properties such as E-modulus and compressive strength.
Journal ArticleDOI
Detecting Gene-Environment Interaction for Maternal Exposures Using Case-Parent Trios Ascertained Through a Case With Non-Syndromic Orofacial Cleft.
Wanying Zhang,Sowmya Venkataraghavan,Jacqueline B. Hetmanski,Elizabeth J. Leslie,Mary L. Marazita,Eleanor Feingold,Seth M. Weinberg,Ingo Ruczinski,Margaret A. Taub,Alan F. Scott,Debashree Ray,Terri H. Beaty +11 more
TL;DR: In this article, case-parent trios ascertained through a proband with a non-syndromic orofacial cleft (OFC) were used to test for possible gene-environment (G × E) interaction between genome-wide markers (both observed and imputed) and self-reported maternal exposure to smoking, alcohol consumption, and multivitamin supplementation during pregnancy.
Journal ArticleDOI
Supportive medication in cancer during pregnancy
TL;DR: This review aims to provide a précis of the current literature regarding both safety and efficacy of all categories of supportive medication during pregnancy.
Journal ArticleDOI
Lower respiratory tract infections and orofacial clefts: a prospective cohort study from the Japan Environment and Children's Study.
Yukihiro Sato,Eiji Yoshioka,Yasuaki Saijo,Toshinobu Miyamoto,Hiroshi Azuma,Yusuke Tanahashi,Yoshiya Ito,Sumitaka Kobayashi,Machiko Minatoya,Yu Ait Bamai,Keiko Yamazaki,Sachiko Ito,Chihiro Miyashita,Atsuko Araki,Reiko Kishi +14 more
TL;DR: In this article, a prospective cohort study used data from the Japan Environment and Children's Study, whose baseline recruitment was conducted during 2011-2014, to examine whether infants with orofacial clefts were associated with LRTIs.
References
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Journal ArticleDOI
Retinoic Acid Embryopathy
TL;DR: It is possible that a major mechanism of isotretinoin teratogenesis is a deleterious effect on cephalic neural-crest cell activity that results in the observed craniofacial, cardiac, and thymic malformations.
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Women and smoking: a report of the Surgeon General.
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Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development.
TL;DR: It is suggested that Apaf1 is essential for Casp3 activation in embryonic brain and is a key regulator of developmental programmed cell death in mammals.
Journal ArticleDOI
Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome.
Virginia Kimonis,Alisa M. Goldstein,B. Pastakia,Mu Yang,Ronald G. Kase,John J. DiGiovanna,Allen E. Bale,Sherri J. Bale +7 more
TL;DR: The frequency of the clinical and radiological anomalies in Nevoid basal cell carcinoma syndrome in a large population of US patients is delineated and guidelines for diagnosis and management are discussed.
Journal ArticleDOI
Transforming growth factor-β3 is required for secondary palate fusion
Gabriele Proetzel,Sharon A. Pawlowski,Michael V. Wiles,Moying Yin,Gregory P. Boivin,Philip N. Howles,Jixang Ding,Mark W. J. Ferguson,Thomas Doetschman +8 more
TL;DR: This result demonstrates that TGF–β3 affects palatal shelf fusion by an intrinsic, primary mechanism rather than by effects secondary to craniofacial defects.
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