Journal ArticleDOI
Cleft lip and palate
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TLDR
Prevention is the ultimate objective for clefts of the lip and palate, and a prerequisite of this aim is to elucidate causes of the disorders.About:
This article is published in The Lancet.The article was published on 2009-11-21. It has received 1344 citations till now. The article focuses on the topics: Oral cleft & IRF6.read more
Citations
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Journal ArticleDOI
Sociodemographic Predictors of Patient Age at Time of Cleft Lip and Palate Repair.
Jeremy V. Lynn,Kavitha Ranganathan,Matthew H. Bageris,Alexandra O. Luby,Hailey R. Tursak,Tami Hart-Johnson,R. Alexander Blackwood,Steven R. Buchman +7 more
TL;DR: By identifying race, Child Protective Services contact, and care variables as significant predictors of increased patient age at time of intervention, multidisciplinary cleft care teams can proactively allocate patient support resources.
Journal ArticleDOI
Clinical, genetic, and molecular characterization of hyperphosphatasia with mental retardation: a case report and literature review
Layal Abi Farraj,Wassim Daoud Khatoun,Naji Abou Chebel,Victor Wakim,Katia Dawali,Michella Ghassibe-Sabbagh +5 more
TL;DR: A pair of monozygotic twins presenting with severe intellectual disability, distinct facial dysmorphism, developmental delay, and increased alkaline phosphatase level are described, illustrating the genomic profile of PGAP3-related HPMRS which is essential for targeted molecular and genetic testing.
Journal ArticleDOI
A review of COVID-19 therapeutics in pregnancy and lactation
TL;DR: In this paper , a review of published data on COVID-19 therapeutics in pregnancy and lactation is presented to help inform clinical decision-making about their use in this population.
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The use of acellular dermal matrix in the closure of oronasal fistulae after cleft palate repair.
TL;DR: Usually, the fistula occurs at the junction of the hard and soft palate, a defect in this location is frequently associated with hypernasality of the speech, velopharyngeal incompetence, and nasal regurgitation of food and liquids with consequent impairment of the quality of life.
Journal ArticleDOI
Impact of breastfeeding and/or bottle-feeding on surgical wound dehiscence after cleft lip repair in infants: A systematic review.
TL;DR: This review showed no increased risk of surgical wound dehiscence in infants with breastfeeding and/or bottle-feeding after cleft lip repair compared with infants with alternative feeding methods.
References
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Journal ArticleDOI
Retinoic Acid Embryopathy
TL;DR: It is possible that a major mechanism of isotretinoin teratogenesis is a deleterious effect on cephalic neural-crest cell activity that results in the observed craniofacial, cardiac, and thymic malformations.
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Women and smoking: a report of the Surgeon General.
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Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development.
TL;DR: It is suggested that Apaf1 is essential for Casp3 activation in embryonic brain and is a key regulator of developmental programmed cell death in mammals.
Journal ArticleDOI
Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome.
Virginia Kimonis,Alisa M. Goldstein,B. Pastakia,Mu Yang,Ronald G. Kase,John J. DiGiovanna,Allen E. Bale,Sherri J. Bale +7 more
TL;DR: The frequency of the clinical and radiological anomalies in Nevoid basal cell carcinoma syndrome in a large population of US patients is delineated and guidelines for diagnosis and management are discussed.
Journal ArticleDOI
Transforming growth factor-β3 is required for secondary palate fusion
Gabriele Proetzel,Sharon A. Pawlowski,Michael V. Wiles,Moying Yin,Gregory P. Boivin,Philip N. Howles,Jixang Ding,Mark W. J. Ferguson,Thomas Doetschman +8 more
TL;DR: This result demonstrates that TGF–β3 affects palatal shelf fusion by an intrinsic, primary mechanism rather than by effects secondary to craniofacial defects.
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