Journal ArticleDOI
Cleft lip and palate
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TLDR
Prevention is the ultimate objective for clefts of the lip and palate, and a prerequisite of this aim is to elucidate causes of the disorders.About:
This article is published in The Lancet.The article was published on 2009-11-21. It has received 1344 citations till now. The article focuses on the topics: Oral cleft & IRF6.read more
Citations
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Journal ArticleDOI
Association of single nucleotide polymorphisms in WNT genes with the risk of nonsyndromic cleft lip with or without cleft palate.
TL;DR: An association between WNT genes polymorphisms and the risk nonsyndromic cleft lip with or without cleft palate in a sample of the southeast Iranian population is suggested.
Journal ArticleDOI
Is It Rare or Common
Kaustubh Adhikari,Taofik AlChawa,Kerstin U. Ludwig,Elisabeth Mangold,Nan M. Laird,Christoph Lange,Christoph Lange +6 more
TL;DR: This paper uses single nucleotide polymorphism (SNP) data in a case‐control setting to predict how many common or rare variants there are, using a Bayesian analysis, to compute posterior probabilities for configurations of rare and/or common variants.
Journal ArticleDOI
Pregnancy and neonatal outcome following an antenatal diagnosis of cleft lip and palate.
Bénédicte Michel,Christian Debauche,Graham J. Hutchings,Pierre Bernard,Jean-Marc Biard,Geneviève François,Bénédicte Bayet,Olivia Williams +7 more
TL;DR: In cases of CL(P), there is a high incidence of associated anomalies detected on antenatal ultrasound and these significantly increase the risk of poor neonatal outcome.
Journal ArticleDOI
Factors Associated With Delay in Cleft Surgery at a Tertiary Children's Hospital in a Major US Metropolitan City.
Jacqueline Stoneburner,Naikhoba C. O. Munabi,Eric S. Nagengast,Madeleine S. Williams,Pedram Goel,Allyn Auslander,Lori K. Howell,Jeffrey A. Hammoudeh,Jeffrey A. Hammoudeh,Mark M. Urata,Mark M. Urata,William P. Magee,William P. Magee,William P. Magee +13 more
TL;DR: In this article, the authors identify factors associated with late cleft repair at a US tertiary children's hospital using a retrospective study of children with CL/P using Children's Hospital Los Angeles (CHLA) re...
Journal Article
An analysis of deformities in revision surgeries for secondary unilateral cleft lip.
TL;DR: Unfavorable scar followed by vermilion notch and short lip were the most common secondary cleft lip deformities and better technique helps favorable scar.
References
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Journal ArticleDOI
Retinoic Acid Embryopathy
TL;DR: It is possible that a major mechanism of isotretinoin teratogenesis is a deleterious effect on cephalic neural-crest cell activity that results in the observed craniofacial, cardiac, and thymic malformations.
Journal ArticleDOI
Women and smoking: a report of the Surgeon General.
Journal ArticleDOI
Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development.
TL;DR: It is suggested that Apaf1 is essential for Casp3 activation in embryonic brain and is a key regulator of developmental programmed cell death in mammals.
Journal ArticleDOI
Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome.
Virginia Kimonis,Alisa M. Goldstein,B. Pastakia,Mu Yang,Ronald G. Kase,John J. DiGiovanna,Allen E. Bale,Sherri J. Bale +7 more
TL;DR: The frequency of the clinical and radiological anomalies in Nevoid basal cell carcinoma syndrome in a large population of US patients is delineated and guidelines for diagnosis and management are discussed.
Journal ArticleDOI
Transforming growth factor-β3 is required for secondary palate fusion
Gabriele Proetzel,Sharon A. Pawlowski,Michael V. Wiles,Moying Yin,Gregory P. Boivin,Philip N. Howles,Jixang Ding,Mark W. J. Ferguson,Thomas Doetschman +8 more
TL;DR: This result demonstrates that TGF–β3 affects palatal shelf fusion by an intrinsic, primary mechanism rather than by effects secondary to craniofacial defects.
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