scispace - formally typeset
T

Tiago R. Magalhaes

Researcher at University College Dublin

Publications -  22
Citations -  7391

Tiago R. Magalhaes is an academic researcher from University College Dublin. The author has contributed to research in topics: Genome-wide association study & Autism. The author has an hindex of 15, co-authored 22 publications receiving 6545 citations. Previous affiliations of Tiago R. Magalhaes include Instituto Gulbenkian de Ciência & University of California, Berkeley.

Papers
More filters
Journal ArticleDOI

Functional impact of global rare copy number variation in autism spectrum disorders

Dalila Pinto, +181 more
- 15 Jul 2010 - 
TL;DR: The genome-wide characteristics of rare (<1% frequency) copy number variation in ASD are analysed using dense genotyping arrays to reveal many new genetic and functional targets in ASD that may lead to final connected pathways.
Journal ArticleDOI

Analysis of shared heritability in common disorders of the brain

Verneri Anttila, +720 more
- 22 Jun 2018 - 
TL;DR: It is demonstrated that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine, and it is shown that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures.
Journal ArticleDOI

Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders

Dalila Pinto, +131 more
- 01 May 2014 - 
TL;DR: For example, the authors analyzed 2,446 ASD-affected families and confirmed an excess of genic deletions and duplications in affected versus control groups (1.41-fold, p = 1.0 × 10(-5)) and an increase in affected subjects carrying exonic pathogenic CNVs overlapping known loci associated with dominant or X-linked ASD and intellectual disability.
Journal ArticleDOI

A genome-wide linkage and association scan reveals novel loci for autism

Lauren A. Weiss, +214 more
- 08 Oct 2009 - 
TL;DR: A linkage and association mapping study using half a million genome-wide single nucleotide polymorphisms in a common set of 1,031 multiplex autism families, implicating SEMA5A as an autism susceptibility gene.
Journal ArticleDOI

A genome-wide scan for common alleles affecting risk for autism

Richard Anney, +170 more
- 15 Oct 2010 - 
TL;DR: In one of four primary association analyses, the association signal for marker rs4141463, located within MACROD2, crossed the genome-wide association significance threshold of P < 5 × 10−8 and, consistent with the winner's curse, its effect size in the replication sample was much smaller.