Universidade Positivo

About: Universidade Positivo is a education organization based out in Curitiba, Brazil. It is known for research contribution in the topics: Population & Medicine. The organization has 1290 authors who have published 1237 publications receiving 9335 citations. The organization is also known as: Positive University.

Prevalence and clinical characteristics of X-linked hypophosphatemia in Paraná, southern Brazil.

Abstract: Objective: The aim of this cross-sectional study was to estimate the prevalence of XLH in Parana, a state in southern Brazil, and report the clinical features and complications of the disease. Materials and methods: We invited all endocrinologists (n = 205), nephrologists (n = 221), orthopedic surgeons (n = 1020), and pediatricians (n = 1000) in Parana to fill out an electronic survey with information on patients with X-linked hypophosphatemia (XLH), and searched the records of the state's health department for all calcitriol prescriptions in 2018. Results: In all, 244 (10%) specialists responded to the email, of whom 18 (7.4%) reported to be taking care of patients with XLH and answered the online survey. A total of 57 patients with XLH were identified (prevalence 5 per million inhabitants). The median age at diagnosis was 22 years, and 42.2% were children and adolescents. Fifteen patients had genetic testing showing a PHEX mutation. Overall, 91.2% had bone deformities, 30.8% had a history of fragility fractures, and 22.4% had renal complications. Conclusion: This study demonstrated a prevalence of XLH of 5 cases per million inhabitants in the state of Parana, a rate lower than the one reported in other countries. Manifestations of renal calcification and bone fragility were frequent among the patients. This is the first epidemiological study evaluating the prevalence and clinical presentation of XLH in Latin America.

Le Fort III osteotomy for severe dentofacial deformity correction associated with hypoplasia of the midface

Abstract: A combinacao da terapia ortodontica com a cirurgia ortognatica e uma modalidade de tratamento bem estabelecida para a correcao de deformidades dentofaciais. Quando estas deformidades apresentam maior severidade, envolvendo a hipoplasia do terco medio da face, exigem tecnicas cirurgicas nao utilizadas como rotina no tratamento das alteracoes faciais, como a osteotomias Le Fort III ou as variacoes destas tecnicas. Poucos estudos relatam o uso desta tecnica ou de suas modificacoes em pacientes nao sindromicos. Este trabalho tem como objetivo demonstrar uma resolucao ortodontica-cirurgica de um paciente apresentando deformidade de face com ma-oclusao Classe III severa, envolvendo hipoplasia do terco medio facial, com a realizacao de uma tecnica modificada da osteotomia Le Fort III, associada as osteotomias Le Fort I e osteotomia sagital dos ramos mandibulares. O paciente encontra-se com tres anos de acompanhamento pos-operatorio, com melhora significativa na sua habilidade mastigatoria, sem queixas funcionais, relatando alta satisfacao com a estetica e melhora na qualidade de vida.

Alteração da temperatura ocular em resposta ao treinamento de corrida em cavalos puro-sangue-inglês no jockey club

Abstract: Durante uma situacao estressante, a termografia infravermelha pode detectar as alteracoes do fluxo sanguineo causadas pela liberacao de catecolaminas e cortisol. O objetivo deste estudo foi avaliar as alteracoes da temperatura ocular associadas ao estresse fisiologico induzido por uma sessao de treinamento de corrida com cavalos Puro-sangue-ingles. Imagens termicas do olho esquerdo de 13 cavalos puro-sangue-ingles foram capturadas antes e depois do exercicio durante o ultimo dia de treinamento antes da primeira corrida oficial dos animais e a temperatura maxima do globo ocular foi analisada. A frequencia respiratoria dos animais foi mensurada antes e apos o exercicio, sendo registradas tambem a temperatura ambiente e a umidade relativa do ar no estabulo e na pista de corrida. O experimento foi realizado em delineamento inteiramente casualizado com 13 repeticoes. As mudancas na temperatura maxima ocular foram analisadas com ANOVA e a correlacao entre a temperatura maxima ocular, a frequencia respiratoria e o indice de conforto termico (IC) foi investigada. Houve aumento significativo (P<0,01) da temperatura ocular apos a sessao de treinamento. Foi encontrada uma correlacao linear positiva entre a frequencia respiratoria e as temperaturas maximas oculares, entretanto nao houve correlacao entre a temperatura ocular e o indice de conforto termico ou entre a frequencia respiratoria e o indice de conforto termico. A termografia infravermelha e capaz de medir efetivamente a mudanca de temperatura do olho, que pode estar relacionada aos niveis de estresse em cavalos puro-sangue durante o treinamento de corrida.

Estimating nutrient loads in the Passaúna reservoir with FLUX

Abstract: The present paper describes an application of the FLUX program to obtain the nutrient loads for the Passauna Reservoir in Curitiba´s Metropolitan Region, in the state of Parana, Brazil. The difficulties and advantages associated with model usage are listed, highlighting the tools available to increase the efficiency of monitoring systems which provide the elements for water quality evaluation models. Estimates of loads in the tributary watersheds are presented, and the associated export coefficients are obtained, indicative of soil use and nutrient-related pollution levels. A comparison of these export coefficients with published values indicates that unaccounted-for non-point sources are likely to exist in the area of study.

Pneumatization within a maxillary sinus graft: a case report.

Abstract: Rehabilitation of edentulous posterior maxilla with implant-supported prostheses frequently presents a challenge to dentists. This is due to insufficient bone within the region, in addition to other limiting factors such as anatomical pneumatization of the maxillary sinus. Thus, grafting of the maxillary sinus is a common procedure used to counteract these problems. Regardless of the type of biomaterial used, the success of the procedure is dependent on the formation of high-quality bone. Therefore, vascularization is a key factor for successful grafting and for the long-term maintenance of the treatment. This paper reports a clinical case of bone graft pneumatization and attempts to elucidate its potential etiology.