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Loukas Moutsianas

Researcher at Wellcome Trust Sanger Institute

Publications -  74
Citations -  16517

Loukas Moutsianas is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Genome-wide association study & Medicine. The author has an hindex of 28, co-authored 49 publications receiving 13675 citations. Previous affiliations of Loukas Moutsianas include University of Oxford & Wellcome Trust Centre for Human Genetics.

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Integrating common and rare genetic variation in diverse human populations

David Altshuler, +68 more
- 02 Sep 2010 - 
TL;DR: An expanded public resource of genome variants in global populations supports deeper interrogation of genomic variation and its role in human disease, and serves as a step towards a high-resolution map of the landscape of human genetic variation.
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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Stephen Sawcer, +265 more
- 10 Aug 2011 - 
TL;DR: In this article, a collaborative GWAS involving 9,772 cases of European descent collected by 23 research groups working in 15 different countries, they have replicated almost all of the previously suggested associations and identified at least a further 29 novel susceptibility loci.
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Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

Ashley Beecham, +206 more
- 01 Nov 2013 - 
TL;DR: This study enhances the catalog of multiple sclerosis risk variants and illustrates the value of fine mapping in the resolution of GWAS signals.
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Mapping copy number variation by population-scale genome sequencing

Ryan E. Mills, +374 more
- 03 Feb 2011 - 
TL;DR: A map of unbalanced SVs is constructed based on whole genome DNA sequencing data from 185 human genomes, integrating evidence from complementary SV discovery approaches with extensive experimental validations, and serves as a resource for sequencing-based association studies.
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Genetic mechanisms of critical illness in Covid-19.

Erola Pairo-Castineira, +1449 more
- 04 Mar 2021 - 
TL;DR: The GenOMICC (Genetics Of Mortality In Critical Care) genome-wide association study in 2244 critically ill Covid-19 patients from 208 UK intensive care units is reported, finding evidence in support of a causal link from low expression of IFNAR2, and high expression of TYK2, to life-threatening disease.