Journal ArticleDOI
A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases.
Stanley Reitman,Sam Frankel +1 more
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This article is published in American Journal of Clinical Pathology.The article was published on 1957-07-01. It has received 9424 citations till now.read more
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Dose-dependent toxicity of CCl4 in isolated rat hepatocytes and the effects of hepatoprotective treatments.
Neill Stacey,Brian G. Priestly +1 more
TL;DR: The findings suggest that the isolated hepatocyte preparation is a suitable model for demonstrating time and dose-dependent toxic effects, but also suggest that there may be differences in mechanism compared with other experimental models.
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The impact of menthol essential oil against inflammation, immunosuppression, and histopathological alterations induced by chlorpyrifos in Nile tilapia.
Mahmoud A.O. Dawood,Abd El-Salam Metwally,Azza H. Elkomy,Mahmoud S. Gewaily,Safaa E. Abdo,Mohamed A.S. Abdel-Razek,Ali A. Soliman,Asem A. Amer,Nagwa I. Abdel-Razik,Hany M.R. Abdel-Latif,Bilal Ahamad Paray +10 more
TL;DR: MNT activated the immunity, antioxidative, and anti-inflammatory responses of Nile tilapia under CPF toxicity, and revealed that inflammation existed in the liver, gills, and intestine oftilapia due to CPFoxicity while MNT protected tissues from inflammation.
Biochemical changes in experimental diabetes before and after treatment with mangifera indica and psidium guava extracts
TL;DR: Investigation of the hypoglycemic effect of Mangifera indica and Psidium guajava aqueous extracts and the effect of glibenclamide as reference sulfonylureas drug revealed great alleviation of the impaired glucose tolerance, serum insulin and hepatic glycogen content, also serum and liver total protein contents were increased as a result of treatment.
Journal ArticleDOI
Evaluation of the protective effect of Nigella sativa extract and its primary active component thymoquinone against DMBA-induced breast cancer in female rats
TL;DR: TQ and then BCS oil reduced the rate of tumor markers, inhibited the histopathological alterations and decreased the expression of the Brca1, Brca2, Id-1 and P53 mutations in mammary tissues of female rats induced by DMBA treatment, suggesting that TQ and BCSOil exert a protective effect against breast carcinogens.
Journal ArticleDOI
Nanosilver toxicity in gills of a neotropical fish: Metal accumulation, oxidative stress, histopathology and other physiological effects
Analía Ale,Carla Bacchetta,Andrea Silvana Rossi,Juan Manuel Galdopórpora,Martín F. Desimone,Fernando R. de la Torre,Susana Graciela Gervasio,Jimena Cazenave +7 more
TL;DR: The results confirmed that the presence of low AgNP concentrations, in short and subchronic exposures, generates alterations in stress biomarkers and in the structure of this vital organ that are the gills.