Journal ArticleDOI
Child developmental risk-factors for adult schizophrenia in the british 1946 birth cohort
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Differences between children destined to develop schizophrenia as adults and the general population were found across a range of developmental domains, and the origins of schizophrenia may be found in early life.About:
This article is published in The Lancet.The article was published on 1994-11-19. It has received 1326 citations till now. The article focuses on the topics: Cohort study & Odds ratio.read more
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The antecedents of non‐affective psychosis in a birth‐cohort, with a focus on measures related to cognitive ability, attentional dysfunction and speech problems
Joy Welham,James Scott,James Scott,Gail M. Williams,Jake M. Najman,William Bor,Michael O'Callaghan,John J. McGrath,John J. McGrath +8 more
TL;DR: The antecedents of non‐affective psychosis in a birth‐cohort are studied with a focus on measures related to cognitive ability, attentional dysfunction, and speech problems.
Journal ArticleDOI
Sensorimotor and cognitive development of infants of mothers with schizophrenia.
TL;DR: Infants of mothers with schizophrenia are likely to have impaired cognitive development, and this may be due in part to environmental factors such as the mother's lifestyle.
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Distinguishing characteristics of subjects with good and poor early outcome in the Edinburgh High-Risk Study.
TL;DR: The good outcome group perform better at baseline in some neuropsychological tests, but there is little neuroanatomical difference, and the poor outcome group show consistently impaired memory function and a tendency to reduction in temporal lobe size.
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A comparison study of early non-psychotic deviant behavior in Afrikaner and US patients with schizophrenia or schizoaffective disorder
TL;DR: It is concluded that early non-psychotic childhood deviance in this independently collected Afrikaner population distinguished a distinct subtype of patients and that the forms of early deviance manifested were meaningfully linked to later disease outcome.
Journal ArticleDOI
Child and adolescent schizophrenia
TL;DR: The study of schizophrenia in childhood or adolescence provides a unique opportunity to examine illness characteristics in the absence of the confounds of substance abuse illness, chronicity, and medication effects.
References
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Journal ArticleDOI
Implications of normal brain development for the pathogenesis of schizophrenia
TL;DR: The findings suggest that nonspecific histopathology exists in the limbic system, diencephalon, and prefrontal cortex, that the pathology occurs early in development, and that the causative process is inactive long before the diagnosis is made.
Book
The strategy of preventive medicine
TL;DR: This chapter discusses the relation of risk to exposure, prevention for individuals and the 'high-risk' strategy, and the population strategy of prevention.
Journal ArticleDOI
Adult Schizophrenia Following Prenatal Exposure to an Influenza Epidemic
TL;DR: It is suggested that it is less the type than the timing of the disturbance during fetal neural development that is critical in determining risk for schizophrenia.
Journal ArticleDOI
Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia.
Richard L. Suddath,George W. Christison,E. Fuller Torrey,Manuel F. Casanova,Daniel R. Weinberger +4 more
TL;DR: In this article, the authors found that subtle abnormalities of cerebral anatomy (namely, small anterior hippocampi and enlarged lateral and third ventricles) are consistent neuropathologic features of schizophrenia and that their cause is at least in part not genetic.
Journal ArticleDOI
Is schizophrenia a neurodevelopmental disorder
Robin M. Murray,Shôn Lewis +1 more
TL;DR: Much research implicates the left rather than the right cerebral hemisphere in schizophrenia, and there is evidence that schizophrenics are more likely to be left handed than controls, and the normal development of lateralised cerebral dominance can be disrupted by premature birth with a resultant increase in left handedness.