Journal ArticleDOI
Child developmental risk-factors for adult schizophrenia in the british 1946 birth cohort
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TLDR
Differences between children destined to develop schizophrenia as adults and the general population were found across a range of developmental domains, and the origins of schizophrenia may be found in early life.About:
This article is published in The Lancet.The article was published on 1994-11-19. It has received 1326 citations till now. The article focuses on the topics: Cohort study & Odds ratio.read more
Citations
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Journal ArticleDOI
Social disadvantage and schizophrenia. A combined neighbourhood and individual-level analysis.
TL;DR: Residents of high social control neighbourhoods may seek greater levels of resolution of psychiatric disorder in patient-residents, and by consequence may induce greater level of inpatient service consumption in patients diagnosed with schizophrenia.
Book ChapterDOI
Epidemiology and Risk Factors for (Tardive) Dyskinesia
TL;DR: Risk factors for TD in the literature are numerous, in this chapter only replicated and risk factors from longitudinal studies will be reported limiting the amount of risk factors.
Journal ArticleDOI
Disturbed synaptic connectivity in schizophrenia: convergence of genetic risk factors during neurodevelopment.
Akiko Hayashi-Takagi,Akira Sawa +1 more
TL;DR: The importance of postnatal glutamate synapse development in the pathology of the disorder is emphasized, and the notion of signal pathways involving more than one genetic factor is in accord with the multifactorial nature of schizophrenia.
Journal ArticleDOI
Height, weight and body mass index in early adulthood and risk of schizophrenia.
Holger J. Sørensen,Erik Lykke Mortensen,Erik Lykke Mortensen,June Machover Reinisch,June Machover Reinisch,S. A. Mednick,S. A. Mednick +6 more
TL;DR: To illuminate the possible associations between height, weight, and body mass index (BMI) during early adulthood and the development of schizophrenia.
Journal ArticleDOI
Does maternal body mass index during pregnancy influence risk of schizophrenia in the adult offspring
TL;DR: In this paper, a qualitative review of the evidence regarding maternal body mass index (BMI) in pregnancy and risk of schizophrenia in adult offspring was conducted and four studies with 305 cases of schizophrenia and 24,442 controls were included.
References
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Journal ArticleDOI
Implications of normal brain development for the pathogenesis of schizophrenia
TL;DR: The findings suggest that nonspecific histopathology exists in the limbic system, diencephalon, and prefrontal cortex, that the pathology occurs early in development, and that the causative process is inactive long before the diagnosis is made.
Book
The strategy of preventive medicine
TL;DR: This chapter discusses the relation of risk to exposure, prevention for individuals and the 'high-risk' strategy, and the population strategy of prevention.
Journal ArticleDOI
Adult Schizophrenia Following Prenatal Exposure to an Influenza Epidemic
TL;DR: It is suggested that it is less the type than the timing of the disturbance during fetal neural development that is critical in determining risk for schizophrenia.
Journal ArticleDOI
Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia.
Richard L. Suddath,George W. Christison,E. Fuller Torrey,Manuel F. Casanova,Daniel R. Weinberger +4 more
TL;DR: In this article, the authors found that subtle abnormalities of cerebral anatomy (namely, small anterior hippocampi and enlarged lateral and third ventricles) are consistent neuropathologic features of schizophrenia and that their cause is at least in part not genetic.
Journal ArticleDOI
Is schizophrenia a neurodevelopmental disorder
Robin M. Murray,Shôn Lewis +1 more
TL;DR: Much research implicates the left rather than the right cerebral hemisphere in schizophrenia, and there is evidence that schizophrenics are more likely to be left handed than controls, and the normal development of lateralised cerebral dominance can be disrupted by premature birth with a resultant increase in left handedness.