Journal ArticleDOI
Child developmental risk-factors for adult schizophrenia in the british 1946 birth cohort
TLDR
Differences between children destined to develop schizophrenia as adults and the general population were found across a range of developmental domains, and the origins of schizophrenia may be found in early life.About:
This article is published in The Lancet.The article was published on 1994-11-19. It has received 1326 citations till now. The article focuses on the topics: Cohort study & Odds ratio.read more
Citations
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Journal ArticleDOI
Obstetrical complications, social class and type of schizophrenia.
TL;DR: An association between OCs and negative symptoms for poor schizophrenic patients, but not for nonpoor patients is indicated, and multivariate logit models further supported this result.
Book ChapterDOI
Controversies in schizophrenia research: the ‘continuum’ challenge, heterogeneity vs homogeneity, and lifetime developmental-‘neuroprogressive’ trajectory
Patrizia A. Baldwin,Robin J. Hennessy,Maria G. Morgan,John Quinn,Paul Scully,John L. Waddington +5 more
TL;DR: A committed and expanding research community, able to apply an increasing armamentarium of molecular genetic, neuropathological, neuroimaging and additional techniques, has made only modest gains over this five-year period.
Journal ArticleDOI
Can we track the impact of Australian mental health research
TL;DR: The status of Australian mental health research is described and potential methods for tracking changes in research output are proposed and Australian researchers need to consider the success of New Zealand and Canadian researchers.
Journal ArticleDOI
Dysthymia in male adolescents is associated with increased risk of later hospitalization for psychotic disorders: a historical-prospective cohort study.
Mark Weiser,Gad Lubin,Asaf Caspi,Asaf Caspi,Jonathan Rabinowitz,M. Shmushkevitz,Rinat Yoffe,Nomi Werbeloff,Demian Halperin,Michael H. Davidson,Michael H. Davidson +10 more
TL;DR: Retrospective studies indicate that patients with psychotic disorders and schizophrenia often suffer from depressive symptoms before the onset of psychosis, and this study studied the association between dysthymia in adolescence and later hospitalization for schizophrenia.
Journal ArticleDOI
Anxious attachment is associated with heightened responsivity of a parietofrontal cortical network that monitors peri-personal space.
Zahra Nasiriavanaki,Tracy Barbour,Amy Farabaugh,Maurizio Fava,Avram J. Holmes,Roger B. H. Tootell,Daphne J. Holt +6 more
TL;DR: In this article, the peripersonal space (PPS) monitoring system was found to vary in responsivity to potentially harmful stimuli, particularly those with social saliency, based on individual differences in attachment styles.
References
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Journal ArticleDOI
Implications of normal brain development for the pathogenesis of schizophrenia
TL;DR: The findings suggest that nonspecific histopathology exists in the limbic system, diencephalon, and prefrontal cortex, that the pathology occurs early in development, and that the causative process is inactive long before the diagnosis is made.
Book
The strategy of preventive medicine
TL;DR: This chapter discusses the relation of risk to exposure, prevention for individuals and the 'high-risk' strategy, and the population strategy of prevention.
Journal ArticleDOI
Adult Schizophrenia Following Prenatal Exposure to an Influenza Epidemic
TL;DR: It is suggested that it is less the type than the timing of the disturbance during fetal neural development that is critical in determining risk for schizophrenia.
Journal ArticleDOI
Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia.
Richard L. Suddath,George W. Christison,E. Fuller Torrey,Manuel F. Casanova,Daniel R. Weinberger +4 more
TL;DR: In this article, the authors found that subtle abnormalities of cerebral anatomy (namely, small anterior hippocampi and enlarged lateral and third ventricles) are consistent neuropathologic features of schizophrenia and that their cause is at least in part not genetic.
Journal ArticleDOI
Is schizophrenia a neurodevelopmental disorder
Robin M. Murray,Shôn Lewis +1 more
TL;DR: Much research implicates the left rather than the right cerebral hemisphere in schizophrenia, and there is evidence that schizophrenics are more likely to be left handed than controls, and the normal development of lateralised cerebral dominance can be disrupted by premature birth with a resultant increase in left handedness.