Journal ArticleDOI
Child developmental risk-factors for adult schizophrenia in the british 1946 birth cohort
TLDR
Differences between children destined to develop schizophrenia as adults and the general population were found across a range of developmental domains, and the origins of schizophrenia may be found in early life.About:
This article is published in The Lancet.The article was published on 1994-11-19. It has received 1326 citations till now. The article focuses on the topics: Cohort study & Odds ratio.read more
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Growth pattern and risk of schizophrenia.
TL;DR: No association between growth characteristics and schizophrenia in families with at least one member with schizophrenia was found, and family-related factors should be taken into account as possible confounders in future studies on growth and schizophrenia.
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How are social-emotional and behavioral competences and problems at age 1 year associated with infant motor development? A general population study.
Susanna Kovaniemi,Jaana Alakortes,Alice S. Carter,Anneli Yliherva,Risto Bloigu,Leena Joskitt,Irma Moilanen,Hanna Ebeling +7 more
TL;DR: In this paper, the authors investigated associations between early competencies and problems, as measured by the Brief Infant-Toddler Social and Emotional Assessment (BITSEA), and the timing of achievement of the main gross and fine motor milestones usually attained during the first year of life in a general population context.
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Trajectories of Early Childhood Developmental Skills and Early Adolescent Psychotic Experiences: Findings from the ALSPAC UK Birth Cohort
TL;DR: In this article, Latent class growth analysis was used to generate trajectories over time for measures of fine and gross motor development, social, and communication skills, and logistic regression was employed to investigate associations between developmental trajectories in each of these early developmental domains and PEs at age 12.
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Schizophrenia: A Long-term Consequence of Hemolytic Disease of the Fetus and Newborn?
TL;DR: The association of OCs with schizophrenia provides great promise since the implication is that at least some types of schizophrenia are preventable or can have a less severe course if improvements in prenatal and perinatal care are made.
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Assessment of the Role of IQ in Associations Between Population Density and Deprivation and Nonaffective Psychosis
Gemma Lewis,Jennifer Dykxhoorn,Håkan Karlsson,Gulam Khandaker,Gulam Khandaker,Glyn Lewis,Christina Dalman,Christina Dalman,James B. Kirkbride +8 more
TL;DR: This cohort study investigates whether lower IQ contributed to the association between population density or deprivation and nonaffective psychosis and whether these associations were stronger in people with lower IQ among Swedish military conscripts.
References
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Journal ArticleDOI
Implications of normal brain development for the pathogenesis of schizophrenia
TL;DR: The findings suggest that nonspecific histopathology exists in the limbic system, diencephalon, and prefrontal cortex, that the pathology occurs early in development, and that the causative process is inactive long before the diagnosis is made.
Book
The strategy of preventive medicine
TL;DR: This chapter discusses the relation of risk to exposure, prevention for individuals and the 'high-risk' strategy, and the population strategy of prevention.
Journal ArticleDOI
Adult Schizophrenia Following Prenatal Exposure to an Influenza Epidemic
TL;DR: It is suggested that it is less the type than the timing of the disturbance during fetal neural development that is critical in determining risk for schizophrenia.
Journal ArticleDOI
Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia.
Richard L. Suddath,George W. Christison,E. Fuller Torrey,Manuel F. Casanova,Daniel R. Weinberger +4 more
TL;DR: In this article, the authors found that subtle abnormalities of cerebral anatomy (namely, small anterior hippocampi and enlarged lateral and third ventricles) are consistent neuropathologic features of schizophrenia and that their cause is at least in part not genetic.
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Is schizophrenia a neurodevelopmental disorder
Robin M. Murray,Shôn Lewis +1 more
TL;DR: Much research implicates the left rather than the right cerebral hemisphere in schizophrenia, and there is evidence that schizophrenics are more likely to be left handed than controls, and the normal development of lateralised cerebral dominance can be disrupted by premature birth with a resultant increase in left handedness.