Journal ArticleDOI
Child developmental risk-factors for adult schizophrenia in the british 1946 birth cohort
Reads0
Chats0
TLDR
Differences between children destined to develop schizophrenia as adults and the general population were found across a range of developmental domains, and the origins of schizophrenia may be found in early life.About:
This article is published in The Lancet.The article was published on 1994-11-19. It has received 1326 citations till now. The article focuses on the topics: Cohort study & Odds ratio.read more
Citations
More filters
Journal ArticleDOI
Schizophrenia is (not simply) a neurodevelopmental disorder.
Paola Dazzan,Robin M. Murray +1 more
TL;DR: Evidence from epidemiological, genetic and neuroimaging studies suggests that schizophrenia is in part a neurodevelopmental disorder, but it is pointed out that this is not the whole story.
Journal ArticleDOI
Association between processing speed and subclinical psychotic symptoms in the general population: focusing on sex differences.
Wulf Rössler,Wulf Rössler,Wulf Rössler,Vladeta Ajdacic-Gross,Vladeta Ajdacic-Gross,Mario Müller,Mario Müller,Stephanie Rodgers,Stephanie Rodgers,Wolfram Kawohl,Helene Haker,Michael Pascal Hengartner,Michael Pascal Hengartner,Michael Pascal Hengartner +13 more
TL;DR: It appears that sex differences in psychosis manifest themselves only at the high end of the continuum (full-blown schizophrenia) and not across the sub-threshold range, conforms to the etiopathology of the disorder.
Journal ArticleDOI
Assessing a minimal executive operation in schizophrenia.
Marie-Laure Grillon,Marcia K. Johnson,Jean-Marie Danion,Lydia Rizzo,Cécile Verdet,Caroline Huron +5 more
TL;DR: The results suggest that although patients with schizophrenia may have some difficulty engaging the refresh process, they show significant long-term memory benefits when induced to do so.
Journal ArticleDOI
Approaches to psychiatric assessment in epidemiological studies of children
TL;DR: An assessment protocol for the longitudinal measurement of developmental psychopathology in a population-based study of children and adolescents is proposed and the recommendations may apply to other psychiatric epidemiological research designs.
Journal ArticleDOI
Increased familiarity of intellectual deficits in early-onset schizophrenia spectrum disorders.
Ximena Goldberg,Mar Fatjó-Vilas,Ma José Muñoz,Sílvia Campanera,Salvador Miret,M. J. Miñano,Mari Aguilera,M. L. Miralles,M.E. Navarro,Luisa Lázaro,Marc Guitart,Neus Barrantes-Vidal,Lourdes Fañanás +12 more
TL;DR: High aggregation of intellectual performance in the EOS group suggests larger familial vulnerability in early-onset forms of the disease when cognitive functions are considered, and within a continuum of psychopathology in schizophrenia spectrum disorders.
References
More filters
Journal ArticleDOI
Implications of normal brain development for the pathogenesis of schizophrenia
TL;DR: The findings suggest that nonspecific histopathology exists in the limbic system, diencephalon, and prefrontal cortex, that the pathology occurs early in development, and that the causative process is inactive long before the diagnosis is made.
Book
The strategy of preventive medicine
TL;DR: This chapter discusses the relation of risk to exposure, prevention for individuals and the 'high-risk' strategy, and the population strategy of prevention.
Journal ArticleDOI
Adult Schizophrenia Following Prenatal Exposure to an Influenza Epidemic
TL;DR: It is suggested that it is less the type than the timing of the disturbance during fetal neural development that is critical in determining risk for schizophrenia.
Journal ArticleDOI
Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia.
Richard L. Suddath,George W. Christison,E. Fuller Torrey,Manuel F. Casanova,Daniel R. Weinberger +4 more
TL;DR: In this article, the authors found that subtle abnormalities of cerebral anatomy (namely, small anterior hippocampi and enlarged lateral and third ventricles) are consistent neuropathologic features of schizophrenia and that their cause is at least in part not genetic.
Journal ArticleDOI
Is schizophrenia a neurodevelopmental disorder
Robin M. Murray,Shôn Lewis +1 more
TL;DR: Much research implicates the left rather than the right cerebral hemisphere in schizophrenia, and there is evidence that schizophrenics are more likely to be left handed than controls, and the normal development of lateralised cerebral dominance can be disrupted by premature birth with a resultant increase in left handedness.