Journal ArticleDOI
Child developmental risk-factors for adult schizophrenia in the british 1946 birth cohort
Reads0
Chats0
TLDR
Differences between children destined to develop schizophrenia as adults and the general population were found across a range of developmental domains, and the origins of schizophrenia may be found in early life.About:
This article is published in The Lancet.The article was published on 1994-11-19. It has received 1326 citations till now. The article focuses on the topics: Cohort study & Odds ratio.read more
Citations
More filters
Journal ArticleDOI
Socioeconomic status as a moderator of the genetic and shared environmental influence on verbal IQ: A multilevel behavioral genetic approach
TL;DR: This article examined the role of school-level socioeconomic status (SES) in moderating genetic and environmental influences on verbal intelligence at the individual level and found that genetic factors have greater influence on IQ in the presence of higher levels of SES.
Journal ArticleDOI
The spectrum of psychosis in multiple sclerosis: a clinical case series
Thomas G Gilberthorpe,Kara E. O’Connell,Alison Carolan,Eli Silber,Peter A Brex,Naomi A. Sibtain,Anthony S. David +6 more
TL;DR: A retrospective case series describes the spectrum of psychotic disorders occurring in association with MS using demographic, clinical, and neuroimaging data to highlight the particular diagnostic and treatment challenges such disorders can pose for clinicians and provide examples of potential interventions for this complex patient population.
Journal ArticleDOI
First psychiatric hospitalizations in the US military: the National Collaborative Study of Early Psychosis and Suicide (NCSEPS).
Richard Herrell,Ioline D. Henter,Ramin Mojtabai,John J. Bartko,Diane Venable,Ezra Susser,Kathleen R. Merikangas,Richard Jet Wyatt +7 more
TL;DR: This study underscores the human and financial burden that psychiatric disorders place on the US Armed Forces.
Journal ArticleDOI
The Neuroanatomy of Verbal Working Memory in Schizophrenia: A Voxel-Based Morphometry Study
Gianfranco Spalletta,Francesco Tomaiuolo,Margherita Di Paola,Alberto Trequattrini,Pietro Bria,Emiliano Macaluso,Richard S. J. Frackowiak,Cario Caltagirone +7 more
TL;DR: Investigating the relationship between verbal working memory performance and cerebral structure in schizophrenic patients and control subjects showed that WM density values in the pars opercularis of the left inferior frontal gyrus were positively and specifically correlated with verbalWorking memory performance in schizop...
Journal ArticleDOI
The association between childhood autistic traits and adolescent psychotic experiences is explained by general neuropsychiatric problems.
Martin Cederlöf,Erik Pettersson,Amir Sariaslan,Henrik Larsson,Per Östberg,Per Östberg,Ian Kelleher,Niklas Långström,Niklas Långström,Clara Hellner Gumpert,Sebastian Lundström,Paul Lichtenstein +11 more
TL;DR: Twin analyses revealed that the association between the general neuropsychiatric problems factor and auditory hallucinations was driven by shared genetic influences, while after controlling for autistic traits, the associations between autistic traits and auditory hallucination disappeared.
References
More filters
Journal ArticleDOI
Implications of normal brain development for the pathogenesis of schizophrenia
TL;DR: The findings suggest that nonspecific histopathology exists in the limbic system, diencephalon, and prefrontal cortex, that the pathology occurs early in development, and that the causative process is inactive long before the diagnosis is made.
Book
The strategy of preventive medicine
TL;DR: This chapter discusses the relation of risk to exposure, prevention for individuals and the 'high-risk' strategy, and the population strategy of prevention.
Journal ArticleDOI
Adult Schizophrenia Following Prenatal Exposure to an Influenza Epidemic
TL;DR: It is suggested that it is less the type than the timing of the disturbance during fetal neural development that is critical in determining risk for schizophrenia.
Journal ArticleDOI
Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia.
Richard L. Suddath,George W. Christison,E. Fuller Torrey,Manuel F. Casanova,Daniel R. Weinberger +4 more
TL;DR: In this article, the authors found that subtle abnormalities of cerebral anatomy (namely, small anterior hippocampi and enlarged lateral and third ventricles) are consistent neuropathologic features of schizophrenia and that their cause is at least in part not genetic.
Journal ArticleDOI
Is schizophrenia a neurodevelopmental disorder
Robin M. Murray,Shôn Lewis +1 more
TL;DR: Much research implicates the left rather than the right cerebral hemisphere in schizophrenia, and there is evidence that schizophrenics are more likely to be left handed than controls, and the normal development of lateralised cerebral dominance can be disrupted by premature birth with a resultant increase in left handedness.