Journal ArticleDOI
Child developmental risk-factors for adult schizophrenia in the british 1946 birth cohort
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Differences between children destined to develop schizophrenia as adults and the general population were found across a range of developmental domains, and the origins of schizophrenia may be found in early life.About:
This article is published in The Lancet.The article was published on 1994-11-19. It has received 1326 citations till now. The article focuses on the topics: Cohort study & Odds ratio.read more
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Journal ArticleDOI
Association between childhood psychiatric disorders and psychotic experiences in adolescence: A population-based longitudinal study
Caroline Siebald,Gulam Khandaker,Gulam Khandaker,Stanley Zammit,Glyn Lewis,Peter B. Jones,Peter B. Jones +6 more
TL;DR: The findings indicate that adolescent PEs are associated with general cognitive ability and past and present psychopathological factors in the population-based prospective ALSPAC birth cohort.
Book ChapterDOI
Epidemiological Aspects of Migration and Mental Illness.
TL;DR: This volume explores all aspects of migration, on all scales, and its effect on mental health and does not limit itself to refugee studies.
Journal ArticleDOI
Psychological and Social Treatments for Schizophrenia: Not Just Old Remedies in New Bottles
David R. Hemsley,Robin M. Murray +1 more
TL;DR: Mental health teams frequently use, and even more frequently claim to use, psychosocial treatments in the care of people with schizophrenia but there remains a suspicion, particularly among patients' and relatives' groups, that such treatments are not as widely available as they ought to be.
Journal ArticleDOI
Psychiatric neuroimaging: Joining forces with epidemiology
TL;DR: In this paper, the use of epidemiological principles to neuroimaging research is a necessary next step in psychiatric research, because of the complexity of mental disorders and the multiple risk factors involved only using of large epidemiologically defined samples will allow to study the broader spectrum of psychopathology, including sub-threshold presentation and explore pathophysiological processes and the functional impact of genetic and non-genetic factors on the onset and persistence of the psychopathology.
Journal ArticleDOI
Effects of paternal age and offspring cognitive ability in early adulthood on the risk of schizophrenia and related disorders
Holger J. Sørensen,Holger J. Sørensen,Carsten Bøcker Pedersen,Carsten Bøcker Pedersen,Merete Nordentoft,Merete Nordentoft,Preben Bo Mortensen,Preben Bo Mortensen,Vera Ehrenstein,Liselotte Petersen,Liselotte Petersen +10 more
TL;DR: There was little evidence of lower premorbid IQ in APA-related SSD (individuals who developed SSD and were also offspring of older fathers), and the results do not support the notion that risk gradient for offspring SSD associated with paternal age is mediated by offspring IQ.
References
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Journal ArticleDOI
Implications of normal brain development for the pathogenesis of schizophrenia
TL;DR: The findings suggest that nonspecific histopathology exists in the limbic system, diencephalon, and prefrontal cortex, that the pathology occurs early in development, and that the causative process is inactive long before the diagnosis is made.
Book
The strategy of preventive medicine
TL;DR: This chapter discusses the relation of risk to exposure, prevention for individuals and the 'high-risk' strategy, and the population strategy of prevention.
Journal ArticleDOI
Adult Schizophrenia Following Prenatal Exposure to an Influenza Epidemic
TL;DR: It is suggested that it is less the type than the timing of the disturbance during fetal neural development that is critical in determining risk for schizophrenia.
Journal ArticleDOI
Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia.
Richard L. Suddath,George W. Christison,E. Fuller Torrey,Manuel F. Casanova,Daniel R. Weinberger +4 more
TL;DR: In this article, the authors found that subtle abnormalities of cerebral anatomy (namely, small anterior hippocampi and enlarged lateral and third ventricles) are consistent neuropathologic features of schizophrenia and that their cause is at least in part not genetic.
Journal ArticleDOI
Is schizophrenia a neurodevelopmental disorder
Robin M. Murray,Shôn Lewis +1 more
TL;DR: Much research implicates the left rather than the right cerebral hemisphere in schizophrenia, and there is evidence that schizophrenics are more likely to be left handed than controls, and the normal development of lateralised cerebral dominance can be disrupted by premature birth with a resultant increase in left handedness.