Journal ArticleDOI
Child developmental risk-factors for adult schizophrenia in the british 1946 birth cohort
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TLDR
Differences between children destined to develop schizophrenia as adults and the general population were found across a range of developmental domains, and the origins of schizophrenia may be found in early life.About:
This article is published in The Lancet.The article was published on 1994-11-19. It has received 1326 citations till now. The article focuses on the topics: Cohort study & Odds ratio.read more
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Dissertation
Étude comparative du fonctionnement dans la communauté des jeunes adultes schizophrènes et de leurs pairs sans psychopathologie
TL;DR: Community functioning of young adults with schizophrenia after the first episode of psychosis is examined and compared with community functioning of their unaffected peers to examine the needs, preferences and priorities in terms of rehabilitation services.
Journal ArticleDOI
Neurodevelopmental influences in the genesis and epigenesis of schizophrenia: An overview
TL;DR: Although the case for viewing schizophrenia as a neurodevelopmental condition is still circumstantial, and several gaps in this model remain, evidence from diverse lines of inquiry converge to indicate at least a partial role of disturbances of brain development in the disorder's genesis and epigenesis.
Journal ArticleDOI
Neurological soft signs in patients with schizophrenia: current knowledge and future perspectives in the post-genomics era
TL;DR: The potential relevance of NSS in the understanding of schizophrenia as a neurodevelopmental disorder, as outcome predictors, as biological markers during several stages of development, and as a candidate (endo)phenotype for genetic analyses are described.
Social phobia and depression in psychosis
TL;DR: Social anxiety in schizophrenia is found to be related to appraisals of the illness as a life event entailing loss, humiliation and entrapment, and implications for psychological interventions and treatments of emotional disorders in psychosis and associated distress are discussed.
Journal ArticleDOI
A longitudinal cohort study of intelligence and later hospitalisation with mental disorder
Stine Schou Mikkelsen,Trine Flensborg-Madsen,Marie Eliasen,Erik Lykke Mortensen,Erik Lykke Mortensen +4 more
TL;DR: Pre-morbid IQ was found to be significantly associated with the development of mental disorder and the interaction between gender and IQ was not statistically significant.
References
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Journal ArticleDOI
Implications of normal brain development for the pathogenesis of schizophrenia
TL;DR: The findings suggest that nonspecific histopathology exists in the limbic system, diencephalon, and prefrontal cortex, that the pathology occurs early in development, and that the causative process is inactive long before the diagnosis is made.
Book
The strategy of preventive medicine
TL;DR: This chapter discusses the relation of risk to exposure, prevention for individuals and the 'high-risk' strategy, and the population strategy of prevention.
Journal ArticleDOI
Adult Schizophrenia Following Prenatal Exposure to an Influenza Epidemic
TL;DR: It is suggested that it is less the type than the timing of the disturbance during fetal neural development that is critical in determining risk for schizophrenia.
Journal ArticleDOI
Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia.
Richard L. Suddath,George W. Christison,E. Fuller Torrey,Manuel F. Casanova,Daniel R. Weinberger +4 more
TL;DR: In this article, the authors found that subtle abnormalities of cerebral anatomy (namely, small anterior hippocampi and enlarged lateral and third ventricles) are consistent neuropathologic features of schizophrenia and that their cause is at least in part not genetic.
Journal ArticleDOI
Is schizophrenia a neurodevelopmental disorder
Robin M. Murray,Shôn Lewis +1 more
TL;DR: Much research implicates the left rather than the right cerebral hemisphere in schizophrenia, and there is evidence that schizophrenics are more likely to be left handed than controls, and the normal development of lateralised cerebral dominance can be disrupted by premature birth with a resultant increase in left handedness.