Journal ArticleDOI
Child developmental risk-factors for adult schizophrenia in the british 1946 birth cohort
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Differences between children destined to develop schizophrenia as adults and the general population were found across a range of developmental domains, and the origins of schizophrenia may be found in early life.About:
This article is published in The Lancet.The article was published on 1994-11-19. It has received 1326 citations till now. The article focuses on the topics: Cohort study & Odds ratio.read more
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Effects of add-on mirtazapine on neurocognition in schizophrenia: a double-blind, randomized, placebo-controlled study
Jan-Henry Stenberg,Viatcheslav Terevnikov,Marina Joffe,Jari Tiihonen,Jari Tiihonen,Evgueni Tchoukhine,Mark Burkin,Grigori Joffe +7 more
TL;DR: Adjunctive mirtazapine might offer a safe, effective and cost-saving option as a neurocognitive enhancer for FGA-treated schizophrenia patients and may become especially useful in light of the currently increasing attention towards FGAs.
Journal ArticleDOI
Duration of untreated psychosis and cognitive functioning.
Charlotte Rapp,Erich Studerus,Hilal Bugra,Jacqueline Aston,Corinne Tamagni,Anna Walter,Marlon O. Pflueger,Stefan Borgwardt,Anita Riecher-Rössler +8 more
TL;DR: This study could not confirm an association betweenduration of untreated psychosis or duration of untreated illness and neurocognitive performance in the ARMS-T and FEP samples, which could be because schizophrenic psychoses are neurodevelopmental disorders in which most cognitive deficits exist long before the onset of psychiatric symptoms.
Journal ArticleDOI
Reconsidering the classification of schizophrenia and manic depressive illness--a critical analysis and new conceptual model.
TL;DR: A hypothetical conceptual approach to the classification of psychoses is proposed that has been greatly informed by the organizing principle underlying the periodic table of the elements, and is distinct from the ‘disease’ model of psychiatric classification.
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Schizophrenia and autism considered as the products of an agnosic right shift gene.
TL;DR: A mechanism for Crow's theory which requires only one new assumption for the right shift genetic model of handedness and cerebral dominance is suggested, which is that the RS+ allele, whose normal function is to induce the left hemisphere to serve speech by impairing speech-related cortex in the right hemisphere, tends to lose its directional coding.
Patent
Method and apparatus for diagnosing schizophrenia and schizophrenia subtype
TL;DR: In this paper, a method and apparatus for diagnosing schizophrenia, schizophrenia disorder subgroup, or predisposition thereto in a test subject is disclosed, which includes the steps of determining an interhemispheric switch rate of the test subject.
References
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Journal ArticleDOI
Implications of normal brain development for the pathogenesis of schizophrenia
TL;DR: The findings suggest that nonspecific histopathology exists in the limbic system, diencephalon, and prefrontal cortex, that the pathology occurs early in development, and that the causative process is inactive long before the diagnosis is made.
Book
The strategy of preventive medicine
TL;DR: This chapter discusses the relation of risk to exposure, prevention for individuals and the 'high-risk' strategy, and the population strategy of prevention.
Journal ArticleDOI
Adult Schizophrenia Following Prenatal Exposure to an Influenza Epidemic
TL;DR: It is suggested that it is less the type than the timing of the disturbance during fetal neural development that is critical in determining risk for schizophrenia.
Journal ArticleDOI
Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia.
Richard L. Suddath,George W. Christison,E. Fuller Torrey,Manuel F. Casanova,Daniel R. Weinberger +4 more
TL;DR: In this article, the authors found that subtle abnormalities of cerebral anatomy (namely, small anterior hippocampi and enlarged lateral and third ventricles) are consistent neuropathologic features of schizophrenia and that their cause is at least in part not genetic.
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Is schizophrenia a neurodevelopmental disorder
Robin M. Murray,Shôn Lewis +1 more
TL;DR: Much research implicates the left rather than the right cerebral hemisphere in schizophrenia, and there is evidence that schizophrenics are more likely to be left handed than controls, and the normal development of lateralised cerebral dominance can be disrupted by premature birth with a resultant increase in left handedness.