Journal ArticleDOI
Child developmental risk-factors for adult schizophrenia in the british 1946 birth cohort
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Differences between children destined to develop schizophrenia as adults and the general population were found across a range of developmental domains, and the origins of schizophrenia may be found in early life.About:
This article is published in The Lancet.The article was published on 1994-11-19. It has received 1326 citations till now. The article focuses on the topics: Cohort study & Odds ratio.read more
Citations
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Journal ArticleDOI
Adverse Childhood Experiences and Hallucinations.
TL;DR: A statistically significant and graded relationship between histories of childhood trauma and histories of hallucinations that was independent of a history of substance abuse is found.
Journal ArticleDOI
Epidemiology of schizophrenia: review of findings and myths.
TL;DR: The major epidemiological features of schizophrenia are reviewed, with particular attention to the recent advances using population-based data and some pervasive misconceptions about schizophrenia epidemiology, such as universal distribution and gender equality are discussed.
Book ChapterDOI
The neuropsychology of schizophrenia
Lydia Krabbendam,Jelle Jolles +1 more
TL;DR: This chapter presents the neuropsychological aspects of schizophrenia, with an emphasis upon the major cognitive and behavioural functions that are affected, and focuses on neurocognitive processes involved in the expression of the disease and elaborate on possibly relevant modulatory factors.
Journal ArticleDOI
Brain structure, genetic liability, and psychotic symptoms in subjects at high risk of developing schizophrenia
Stephen M. Lawrie,Heather C. Whalley,Suheib S. Abukmeil,Julia N Kestelman,Lorna Donnelly,Patrick Miller,Jonathan J.K. Best,D. G. C. Owens,Eve C. Johnstone +8 more
TL;DR: The results suggest that some structural abnormalities in subjects at high risk of developing schizophrenia have abnormalities of brain structure similar to but not identical to those found in schizophrenia, and that the development of symptoms is associated with a third overlapping group of structural changes.
Journal ArticleDOI
Prenatal rubella, premorbid abnormalities, and adult schizophrenia
Alan S. Brown,Patricia Cohen,Jill M. Harkavy-Friedman,Vicki P. Babulas,Dolores Malaspina,Jack M. Gorman,Ezra Susser +6 more
TL;DR: These findings link a known prenatal exposure, a deviant neurodevelopmental trajectory in childhood and adolescence, and SSP in adulthood within the same individuals.
References
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Journal ArticleDOI
Implications of normal brain development for the pathogenesis of schizophrenia
TL;DR: The findings suggest that nonspecific histopathology exists in the limbic system, diencephalon, and prefrontal cortex, that the pathology occurs early in development, and that the causative process is inactive long before the diagnosis is made.
Book
The strategy of preventive medicine
TL;DR: This chapter discusses the relation of risk to exposure, prevention for individuals and the 'high-risk' strategy, and the population strategy of prevention.
Journal ArticleDOI
Adult Schizophrenia Following Prenatal Exposure to an Influenza Epidemic
TL;DR: It is suggested that it is less the type than the timing of the disturbance during fetal neural development that is critical in determining risk for schizophrenia.
Journal ArticleDOI
Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia.
Richard L. Suddath,George W. Christison,E. Fuller Torrey,Manuel F. Casanova,Daniel R. Weinberger +4 more
TL;DR: In this article, the authors found that subtle abnormalities of cerebral anatomy (namely, small anterior hippocampi and enlarged lateral and third ventricles) are consistent neuropathologic features of schizophrenia and that their cause is at least in part not genetic.
Journal ArticleDOI
Is schizophrenia a neurodevelopmental disorder
Robin M. Murray,Shôn Lewis +1 more
TL;DR: Much research implicates the left rather than the right cerebral hemisphere in schizophrenia, and there is evidence that schizophrenics are more likely to be left handed than controls, and the normal development of lateralised cerebral dominance can be disrupted by premature birth with a resultant increase in left handedness.