Journal ArticleDOI
Child developmental risk-factors for adult schizophrenia in the british 1946 birth cohort
Reads0
Chats0
TLDR
Differences between children destined to develop schizophrenia as adults and the general population were found across a range of developmental domains, and the origins of schizophrenia may be found in early life.About:
This article is published in The Lancet.The article was published on 1994-11-19. It has received 1326 citations till now. The article focuses on the topics: Cohort study & Odds ratio.read more
Citations
More filters
Journal ArticleDOI
Parental Communication and Psychosis: A Meta-analysis
TL;DR: CD is highly prevalent in parents of psychotic offspring in the broader context of adoption and longitudinal studies that have reported a G × E interaction in the development of psychosis and thought disorder.
Journal ArticleDOI
Gsx1 expression defines neurons required for prepulse inhibition.
TL;DR: A novel genetic screen in larval zebrafish is used to reveal the molecular identity of neurons that are required for prepulse inhibition of the startle response and reveals a molecular link between control of interneuron specification and circuits that gate sensory information across brain regions.
Journal ArticleDOI
Childhood mental ability and lifetime psychiatric contact: A 66-year follow-up study of the 1932 Scottish Mental Ability Survey
TL;DR: In this article, the authors test the hypothesis that intelligence is related to the risk of mental illness by linking childhood mental ability data to registers of psychiatric contact within a stable population in northeast Scotland.
Journal ArticleDOI
Academic deterioration prior to first episode schizophrenia in young Singaporean males
Yong Guan Ang,Hao Yang Tan +1 more
TL;DR: The FES group had greater deterioration in mathematics scores and poorer educational outcome, possibly reflecting neurocognitive changes that preceded the onset of schizophrenia.
Journal ArticleDOI
Symptoms of depression and anxiety, and change in body mass index from adolescence to adulthood: results from a British birth cohort
TL;DR: Adolescence may be an important period for the development of the association between affective symptoms and weight gain in girls, and intervention to prevent increases in BMI across adult life in women with adolescent-onset symptoms should be considered.
References
More filters
Journal ArticleDOI
Implications of normal brain development for the pathogenesis of schizophrenia
TL;DR: The findings suggest that nonspecific histopathology exists in the limbic system, diencephalon, and prefrontal cortex, that the pathology occurs early in development, and that the causative process is inactive long before the diagnosis is made.
Book
The strategy of preventive medicine
TL;DR: This chapter discusses the relation of risk to exposure, prevention for individuals and the 'high-risk' strategy, and the population strategy of prevention.
Journal ArticleDOI
Adult Schizophrenia Following Prenatal Exposure to an Influenza Epidemic
TL;DR: It is suggested that it is less the type than the timing of the disturbance during fetal neural development that is critical in determining risk for schizophrenia.
Journal ArticleDOI
Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia.
Richard L. Suddath,George W. Christison,E. Fuller Torrey,Manuel F. Casanova,Daniel R. Weinberger +4 more
TL;DR: In this article, the authors found that subtle abnormalities of cerebral anatomy (namely, small anterior hippocampi and enlarged lateral and third ventricles) are consistent neuropathologic features of schizophrenia and that their cause is at least in part not genetic.
Journal ArticleDOI
Is schizophrenia a neurodevelopmental disorder
Robin M. Murray,Shôn Lewis +1 more
TL;DR: Much research implicates the left rather than the right cerebral hemisphere in schizophrenia, and there is evidence that schizophrenics are more likely to be left handed than controls, and the normal development of lateralised cerebral dominance can be disrupted by premature birth with a resultant increase in left handedness.