NEC

About: NEC is a company organization based out in Tokyo, Japan. It is known for research contribution in the topics: Signal & Layer (electronics). The organization has 33269 authors who have published 57670 publications receiving 835952 citations. The organization is also known as: NEC Corporation & NEC Electronics Corporation.

System-level exploration for pareto-optimal configurations in parameterized systems-on-a-chip

Abstract: In this work, we provide a technique for efficiently exploring the configuration space of a parameterized system-on-a-chip (SOC) architecture to find all Pareto-optimal configurations. These configurations represent the range of meaningful power and performance tradeoffs that are obtainable by adjusting parameter values for a fixed application mapped onto the SOC architecture. Our approach extensively prunes the potentially large configuration space by taking advantage of parameter dependencies. We have successfully incorporated our technique into the parameterized SOC tuning environment (Platune) and applied it to a number of applications.

Supervised consensus scoring for docking and virtual screening.

Abstract: Docking programs are widely used to discover novel ligands efficiently and can predict protein-ligand complex structures with reasonable accuracy and speed. However, there is an emerging demand for better performance from the scoring methods. Consensus scoring (CS) methods improve the performance by compensating for the deficiencies of each scoring function. However, conventional CS and existing scoring functions have the same problems, such as a lack of protein flexibility, inadequate treatment of salvation, and the simplistic nature of the energy function used. Although there are many problems in current scoring functions, we focus our attention on the incorporation of unbound ligand conformations. To address this problem, we propose supervised consensus scoring (SCS), which takes into account protein-ligand binding process using unbound ligand conformations with supervised learning. An evaluation of docking accuracy for 100 diverse protein-ligand complexes shows that SCS outperforms both CS and 11 scoring functions (PLP, F-Score, LigScore, DrugScore, LUDI, X-Score, AutoDock, PMF, G-Score, ChemScore, and D-score). The success rates of SCS range from 89% to 91% in the range of rmsd < 2 A, while those of CS range from 80% to 85%, and those of the scoring functions range from 26% to 76%. Moreover, we also introduce a method for judging whether a compound is active or inactive with the appropriate criterion for virtual screening. SCS performs quite well in docking accuracy and is presumably useful for screening large-scale compound databases before predicting binding affinity.

Semiconductor device and method of manufacturing the same

Abstract: A semiconductor device of the present invention includes a chip which has a pad; a bump electrode formed on the pad; and a wire whose stitch bonding is made on the bump electrode. The wire satisfies a condition: (modulus-of-elasticity/breaking strength per unit area) >=400.

Video server and video-on-demand system capable of effectively transmitting a special video program

Abstract: In a video server used for a video-on-demand system, a special video program, such as a commercial video program, is transmitted from a special video storage unit of the video server to each subscriber terminal within a nontransmission time which takes place during a searching time for a video program requested by the subscriber and/or during an execution time of a specific reproduction control command, such as a "FAST-FORWARD" command, a "FAST-REWIND" command. The transmission of the special video program is not stopped even when a reproduction control command is given from the subscriber to the special video storage unit by judging the reproduction control command to be invalid while a reproduction control command related to video programs different from the special video program is executed by judging the commands to be valid.

Mobile communication system with cell-site switching for intra-cell handoff

Abstract: In a TDMA cellular mobile communication system, incoming signals from the public switched network are converted by speech coder/data compressor units of a MTSO (mobile telephone switching office) to low-bit-rate signals and combined into a first TDM signal for transmission to a base station. The components of the first TDM signal are respectively routed according to a channel assignment signal and fed into desired modulators which are periodically activated according to the channel assignment signal to transmit signals on assigned channels to mobile units. Signals from the mobile units are received by demodulators at the base station and combined into a second TDM signal which is transmitted to the MTSO. The components of the second TDM signal are routed according to the channel assignment signal to appropriate speech decoder/data expander units for conversion to the original high-bit-rate signals for transmission to the network.