H
Henry Völzke
Researcher at Greifswald University Hospital
Publications - 1093
Citations - 79204
Henry Völzke is an academic researcher from Greifswald University Hospital. The author has contributed to research in topics: Population & Study of Health in Pomerania. The author has an hindex of 115, co-authored 991 publications receiving 64260 citations. Previous affiliations of Henry Völzke include Group Health Cooperative & Umeå University.
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Journal ArticleDOI
Subclinical Hyperthyroidism and the Risk of Coronary Heart Disease and Mortality
Tinh-Hai Collet,Jacobijn Gussekloo,Douglas C. Bauer,Wendy P. J. den Elzen,Anne R. Cappola,Philippe Balmer,Giorgio Iervasi,Bjørn Olav Åsvold,José Augusto Sgarbi,Henry Völzke,Baris Gencer,Rui M. B. Maciel,Sabrina Molinaro,Alexandra Bremner,Robert Luben,Patrick Maisonneuve,Jacques Cornuz,Anne B. Newman,Kay-Tee Khaw,Rudi G. J. Westendorp,Jayne A. Franklyn,Eric Vittinghoff,John P. Walsh,Nicolas Rodondi +23 more
TL;DR: Endogenous subclinical hyperthyroidism is associated with increased risks of total,CHD mortality, and incident AF, with highest risks of CHD mortality and AF when thyrotropin level is lower than 0.10 mIU/L.
Journal ArticleDOI
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits
Joshua C. Randall,Joshua C. Randall,Thomas W. Winkler,Zoltán Kutalik,Zoltán Kutalik,Sonja I. Berndt,Anne U. Jackson,Keri L. Monda,Tuomas O. Kilpeläinen,Tõnu Esko,Reedik Mägi,Reedik Mägi,Shengxu Li,Shengxu Li,Tsegaselassie Workalemahu,Mary F. Feitosa,Damien C. Croteau-Chonka,Felix R. Day,Tove Fall,Teresa Ferreira,Stefan Gustafsson,Adam E. Locke,Iain Mathieson,André Scherag,Sailaja Vedantam,Sailaja Vedantam,Andrew R. Wood,Liming Liang,Valgerdur Steinthorsdottir,Gudmar Thorleifsson,Emmanouil T. Dermitzakis,Antigone S. Dimas,Antigone S. Dimas,Antigone S. Dimas,Fredrik Karpe,Josine L. Min,George Nicholson,Deborah J. Clegg,Thomas N. Person,Jon P. Krohn,Sabrina Bauer,Christa Buechler,Kristina Eisinger,Amélie Bonnefond,Philippe Froguel,Philippe Froguel,Jouke-Jan Hottenga,Inga Prokopenko,Lindsay L. Waite,Tamara B. Harris,Albert V. Smith,Alan R. Shuldiner,Alan R. Shuldiner,Wendy L. McArdle,Mark J. Caulfield,Patricia B. Munroe,Henrik Grönberg,Yii-Der Ida Chen,Yii-Der Ida Chen,Guo Li,Jacques S. Beckmann,Toby Johnson,Toby Johnson,Toby Johnson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Maris Teder-Laving,Kay-Tee Khaw,Nicholas J. Wareham,Jing Hua Zhao,Najaf Amin,Ben A. Oostra,Aldi T. Kraja,Michael A. Province,L. Adrienne Cupples,Nancy L. Heard-Costa,Jaakko Kaprio,Jaakko Kaprio,Samuli Ripatti,Samuli Ripatti,Samuli Ripatti,Ida Surakka,Ida Surakka,Francis S. Collins,Jouko Saramies,Jaakko Tuomilehto,Antti Jula,Veikko Salomaa,Jeanette Erdmann,Christian Hengstenberg,Christina Loley,Heribert Schunkert,Claudia Lamina,H.-Erich Wichmann,Eva Albrecht,Christian Gieger,Andrew A. Hicks,Åsa Johansson,Peter P. Pramstaller,Sekar Kathiresan,Sekar Kathiresan,Elizabeth K. Speliotes,Brenda W.J.H. Penninx,Anna-Liisa Hartikainen,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Ulf Gyllensten,Dorret I. Boomsma,Harry Campbell,James F. Wilson,Stephen J. Chanock,Martin Farrall,Anuj Goel,Carolina Medina-Gomez,Fernando Rivadeneira,Karol Estrada,André G. Uitterlinden,Albert Hofman,M. Carola Zillikens,Martin den Heijer,Lambertus A. Kiemeney,Andrea Maschio,Per Hall,Jonathan Tyrer,Alexander Teumer,Henry Völzke,Peter Kovacs,Anke Tönjes,Massimo Mangino,Tim D. Spector,Caroline Hayward,Igor Rudan,Alistair S. Hall,Nilesh J. Samani,Nilesh J. Samani,Antony P. Attwood,Antony P. Attwood,Jennifer G. Sambrook,Jennifer G. Sambrook,Joseph Hung,Joseph Hung,Lyle J. Palmer,Lyle J. Palmer,Marja-Liisa Lokki,Juha Sinisalo,Gabrielle Boucher,Heikki V. Huikuri,Mattias Lorentzon,Claes Ohlsson,Niina Eklund,Niina Eklund,Johan G. Eriksson,Johan G. Eriksson,Cristina Barlassina,Carlo Rivolta,Ilja M. Nolte,Harold Snieder,Melanie M. van der Klauw,Jana V. van Vliet-Ostaptchouk,Pablo V. Gejman,Jianxin Shi,Kevin B. Jacobs,Kevin B. Jacobs,Zhaoming Wang,Zhaoming Wang,Stephan J. L. Bakker,Irene Mateo Leach,Gerjan Navis,Pim van der Harst,Nicholas G. Martin,Sarah E. Medland,Grant W. Montgomery,Jian Yang,Daniel I. Chasman,Paul M. Ridker,Lynda M. Rose,Terho Lehtimäki,Olli T. Raitakari,Devin Absher,Carlos Iribarren,Hanneke Basart,Kees Hovingh,Elina Hyppönen,Chris Power,Denise Anderson,Denise Anderson,John Beilby,John Beilby,Jennie Hui,Jennie Hui,Jennifer Jolley,Hendrik B. Sager,Stefan R. Bornstein,Peter Schwarz,Kati Kristiansson,Kati Kristiansson,Markus Perola,Markus Perola,Markus Perola,Jaana Lindström,Amy J. Swift,Matti Uusitupa,Mustafa Atalay,Timo A. Lakka,Rainer Rauramaa,Jennifer L. Bolton,Gerry Fowkes,Ross M. Fraser,Jackie F. Price,Krista Fischer,Kaarel KrjutÅkov,Andres Metspalu,Evelin Mihailov,Claudia Langenberg,Claudia Langenberg,Jian'an Luan,Ken K. Ong,Ken K. Ong,Peter S. Chines,Sirkka Keinänen-Kiukaanniemi,Timo Saaristo,Sarah Edkins,Paul W. Franks,Paul W. Franks,Paul W. Franks,Göran Hallmans,Dmitry Shungin,Dmitry Shungin,Andrewvid da Morris,Colin N. A. Palmer,Raimund Erbel,Susanne Moebus,Markus M. Nöthen,Sonali Pechlivanis,Kristian Hveem,Narisu Narisu,Anders Hamsten,Steve E. Humphries,Rona J. Strawbridge,Elena Tremoli,Harald Grallert,Barbara Thorand,Thomas Illig,Wolfgang Koenig,Martina Müller-Nurasyid,Annette Peters,Bernhard O. Boehm,Marcus E. Kleber,Winfried März,Winfried März,Bernhard R. Winkelmann,Johanna Kuusisto,Markku Laakso,Dominique Arveiler,Giancarlo Cesana,Kari Kuulasmaa,Jarmo Virtamo,John Yarnell,Diana Kuh,Andrew Wong,Lars Lind,Ulf de Faire,Bruna Gigante,Patrik K. E. Magnusson,Nancy L. Pedersen,George Dedoussis,Maria Dimitriou,Genovefa Kolovou,Stavroula Kanoni,Kathleen Stirrups,Lori L. Bonnycastle,Inger Njølstad,Tom Wilsgaard,Andrea Ganna,Emil Rehnberg,Aroon D. Hingorani,Mika Kivimäki,Meena Kumari,Themistocles L. Assimes,Inês Barroso,Inês Barroso,Michael Boehnke,Ingrid B. Borecki,Panos Deloukas,Caroline S. Fox,Timothy M. Frayling,Leif Groop,Talin Haritunians,David J. Hunter,Erik Ingelsson,Robert C. Kaplan,Karen L. Mohlke,Jeffrey R. O'Connell,David Schlessinger,David P. Strachan,Kari Stefansson,Kari Stefansson,Cornelia M. van Duijn,Cornelia M. van Duijn,Gonçalo R. Abecasis,Mark I. McCarthy,Joel N. Hirschhorn,Joel N. Hirschhorn,Lu Qi,Ruth J. F. Loos,Cecilia M. Lindgren,Kari E. North,Iris M. Heid +308 more
TL;DR: The value of sex-specific GWAS to unravel the sexually dimorphic genetic underpinning of complex traits is demonstrated, with no evidence for genetic effects with opposite directions in men versus women.
Journal ArticleDOI
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
María Soler Artigas,Daan W. Loth,Louise V. Wain,Sina A. Gharib,Ma'en Obeidat,Wenbo Tang,Guangju Zhai,Guangju Zhai,Jing Hua Zhao,Albert V. Smith,Jennifer E. Huffman,Eva Albrecht,C.M. Jackson,David M. Evans,Gemma Cadby,Gemma Cadby,Myriam Fornage,Ani Manichaikul,Lorna M. Lopez,Toby Johnson,Melinda C. Aldrich,Thor Aspelund,Ins Barroso,Ins Barroso,Harry Campbell,Patricia A. Cassano,David Couper,Gudny Eiriksdottir,Nora Franceschini,Melissa E. Garcia,Christian Gieger,Gauti Kjartan Gislason,Ivica Grković,Christopher J Hammond,Dana B. Hancock,Dana B. Hancock,Tamara B. Harris,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Susan R. Heckbert,Susan R. Heckbert,Markku Heliövaara,Georg Homuth,Pirro G. Hysi,Alan James,Alan James,Stipan Janković,Bonnie R. Joubert,Stefan Karrasch,Norman Klopp,Beate Koch,Stephen B. Kritchevsky,Lenore J. Launer,Yongmei Liu,Laura R. Loehr,Kurt Lohman,Ruth J. F. Loos,Thomas Lumley,Khalid A. Al Balushi,Wei Ang,R. Graham Barr,John Beilby,John D Blakey,Mladen Boban,Vesna Boraska,Jonas Brisman,John Britton,Guy Brusselle,Cyrus Cooper,Ivan Curjuric,Santosh Dahgam,Ian J. Deary,Shah Ebrahim,Mark Eijgelsheim,Clyde Francks,Darya Gaysina,Raquel Granell,Xiangjun Gu,John L. Hankinson,Rebecca Hardy,Sarah E. Harris,John Henderson,Amanda P. Henry,Aroon D. Hingorani,Albert Hofman,Patrick G. Holt,Jennie Hui,Jennie Hui,Michael Hunter,Michael Hunter,Medea Imboden,Karen A. Jameson,Shona M. Kerr,Ivana Kolcic,Florian Kronenberg,Jason Z. Liu,Jonathan Marchini,Tricia M. McKeever,Andrew D. Morris,Anna-Carin Olin,David J. Porteous,Dirkje S. Postma,Stephen S. Rich,Susan M. Ring,Fernando Rivadeneira,Thierry Rochat,Avan Aihie Sayer,Ian Sayers,Peter D. Sly,George Davey Smith,Akshay Sood,John M. Starr,André G. Uitterlinden,Judith M. Vonk,S. Goya Wannamethee,Peter H. Whincup,Cisca Wijmenga,O. Dale Williams,Andrew Wong,Massimo Mangino,Kristin D. Marciante,Wendy L. McArdle,Bernd Meibohm,Alanna C. Morrison,Kari E. North,Ernst Omenaas,Lyle J. Palmer,Lyle J. Palmer,Kirsi H. Pietiläinen,Isabelle Pin,Ozren Polasek,Anneli Pouta,Bruce M. Psaty,Bruce M. Psaty,Anna-Liisa Hartikainen,Taina Rantanen,Samuli Ripatti,Samuli Ripatti,Jerome I. Rotter,Igor Rudan,Igor Rudan,Alicja R. Rudnicka,Holger Schulz,So-Youn Shin,Tim D. Spector,Ida Surakka,Ida Surakka,Veronique Vitart,Henry Völzke,Nicholas J. Wareham,Nicole M. Warrington,Nicole M. Warrington,H.-Erich Wichmann,Sarah H. Wild,Jemma B. Wilk,Matthias Wjst,Alan F. Wright,Lina Zgaga,Lina Zgaga,Tatijana Zemunik,Craig E. Pennell,Fredrik Nyberg,Fredrik Nyberg,Diana Kuh,John W. Holloway,H. Marike Boezen,Debbie A Lawlor,Richard W Morris,Nicole Probst-Hensch,Jaakko Kaprio,Jaakko Kaprio,James F. Wilson,Caroline Hayward,Mika Kähönen,Joachim Heinrich,Arthur W. Musk,Arthur W. Musk,Deborah Jarvis,Deborah Jarvis,Sven Gläser,Sven Gläser,Marjo-Riitta Järvelin,Bruno H. Ch. Stricker,Bruno H. Ch. Stricker,Paul Elliott,Paul Elliott,George T. O'Connor,George T. O'Connor,David P. Strachan,Stephanie J. London,Ian P. Hall,Vilmundur Gudnason,Martin D. Tobin +192 more
TL;DR: This article identified new regions showing association with pulmonary function in or near MFAP2, TGFB2, HDAC4, RARB, MECOM (also known as EVI1), SPATA9, ARMC2, NCR3, ZKSCAN3, CDC123, C10orf11, LRP1, CCDC38, MMP15, CFDP1 and KCNE2.
Journal ArticleDOI
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk
Felix R. Day,Deborah J. Thompson,Hannes Helgason,Hannes Helgason,Daniel I. Chasman,Hilary K. Finucane,Hilary K. Finucane,Patrick Sulem,Katherine S. Ruth,Sean Whalen,Abhishek Sarkar,Abhishek Sarkar,Eva Albrecht,Elisabeth Altmaier,Marzyeh Amini,Caterina Barbieri,Thibaud Boutin,Archie Campbell,Ellen W. Demerath,Ayush Giri,Chunyan He,Jouke J. Hottenga,Robert Karlsson,Ivana Kolcic,Po-Ru Loh,Po-Ru Loh,Kathryn L. Lunetta,Kathryn L. Lunetta,Massimo Mangino,Massimo Mangino,Brumat Marco,George McMahon,Sarah E. Medland,Ilja M. Nolte,Raymond Noordam,Teresa Nutile,Lavinia Paternoster,Natalia Perjakova,Eleonora Porcu,Lynda M. Rose,Katharina E. Schraut,Ayellet V. Segrè,Albert V. Smith,Lisette Stolk,Alexander Teumer,Irene L. Andrulis,Stefania Bandinelli,Matthias W. Beckmann,Javier Benitez,Sven Bergmann,Sven Bergmann,Murielle Bochud,Eric Boerwinkle,Stig E. Bojesen,Manjeet K. Bolla,Judith S. Brand,Hiltrud Brauch,Hiltrud Brauch,Hiltrud Brauch,Hermann Brenner,Linda Broer,Thomas Brüning,Julie E. Buring,Harry Campbell,Eulalia Catamo,Stephen J. Chanock,Georgia Chenevix-Trench,Tanguy Corre,Tanguy Corre,Fergus J. Couch,Diana L. Cousminer,Angela Cox,Laura Crisponi,Kamila Czene,George Davey Smith,Eco J. C. de Geus,Renée de Mutsert,Immaculata De Vivo,Joe Dennis,Peter Devilee,Isabel dos-Santos-Silva,Alison M. Dunning,Johan G. Eriksson,Peter A. Fasching,Peter A. Fasching,Lindsay Fernández-Rhodes,Luigi Ferrucci,Dieter Flesch-Janys,Lude Franke,Marike Gabrielson,Ilaria Gandin,Graham G. Giles,Graham G. Giles,Harald Grallert,Daniel F. Gudbjartsson,Daniel F. Gudbjartsson,Pascal Guénel,Per Hall,Emily Hallberg,Ute Hamann,Tamara B. Harris,Catharina A. Hartman,Gerardo Heiss,Maartje J. Hooning,John L. Hopper,Frank B. Hu,David J. Hunter,M. Arfan Ikram,Hae Kyung Im,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Peter K. Joshi,David Karasik,Manolis Kellis,Manolis Kellis,Zoltán Kutalik,Zoltán Kutalik,Genevieve Lachance,Diether Lambrechts,Claudia Langenberg,Lenore J. Launer,Joop S.E. Laven,Stefania Lenarduzzi,Jingmei Li,Penelope A. Lind,Sara Lindström,Yongmei Liu,Jian'an Luan,Reedik Mägi,Arto Mannermaa,Hamdi Mbarek,Mark I. McCarthy,Christa Meisinger,Thomas Meitinger,Cristina Menni,Andres Metspalu,Kyriaki Michailidou,Kyriaki Michailidou,Lili Milani,Roger L. Milne,Roger L. Milne,Grant W. Montgomery,Anna Marie Mulligan,Mike A. Nalls,Pau Navarro,Heli Nevanlinna,Dale R. Nyholt,Albertine J. Oldehinkel,Tracy A. O'Mara,Sandosh Padmanabhan,Aarno Palotie,Nancy L. Pedersen,Annette Peters,Julian Peto,Paul D.P. Pharoah,Anneli Pouta,Paolo Radice,Iffat Rahman,Susan M. Ring,Antonietta Robino,Frits R. Rosendaal,Igor Rudan,Rico Rueedi,Rico Rueedi,Daniela Ruggiero,Cinzia Sala,Marjanka K. Schmidt,Robert A. Scott,Mitul Shah,Rossella Sorice,Melissa C. Southey,Ulla Sovio,Ulla Sovio,Meir J. Stampfer,Maristella Steri,Konstantin Strauch,Toshiko Tanaka,Emmi Tikkanen,Nicholas J. Timpson,Michela Traglia,Thérèse Truong,Jonathan Tyrer,André G. Uitterlinden,Digna R. Velez Edwards,Veronique Vitart,Uwe Völker,Peter Vollenweider,Qin Wang,Elisabeth Widen,Ko Willems van Dijk,Gonneke Willemsen,Robert Winqvist,Bruce H. R. Wolffenbuttel,Jing Hua Zhao,Magdalena Zoledziewska,Marek Zygmunt,Behrooz Z. Alizadeh,Dorret I. Boomsma,Marina Ciullo,Francesco Cucca,Tõnu Esko,Tõnu Esko,Nora Franceschini,Christian Gieger,Vilmundur Gudnason,Caroline Hayward,Peter Kraft,Debbie A Lawlor,Patrik K. E. Magnusson,Nicholas G. Martin,Dennis O. Mook-Kanamori,Ellen A. Nohr,Ozren Polasek,David J. Porteous,Alkes L. Price,Alkes L. Price,Alkes L. Price,Paul M. Ridker,Harold Snieder,Tim D. Spector,Doris Stöckl,Daniela Toniolo,Sheila Ulivi,Jenny A. Visser,Henry Völzke,Nicholas J. Wareham,James F. Wilson,Amanda B. Spurdle,Unnur Thorsteindottir,Unnur Thorsteindottir,Katherine S. Pollard,Katherine S. Pollard,Douglas F. Easton,Joyce Y. Tung,Jenny Chang-Claude,Jenny Chang-Claude,David A. Hinds,Anna Murray,Joanne M. Murabito,Joanne M. Murabito,Kari Stefansson,Kari Stefansson,Ken K. Ong,John R. B. Perry +244 more
TL;DR: In this article, the authors used 1000 Genomes Project-imputed genotype data in up to ∼370,000 women to identify 389 independent signals (P < 5 × 10-8) for age at menarche, a milestone in female pubertal development.
Journal ArticleDOI
A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis
Stephan Buch,Felix Stickel,Eric Trepo,Michael J. Way,A Herrmann,Hans Dieter Nischalke,Mario Brosch,Jonas Rosendahl,Thomas Berg,Monika Ridinger,Marcella Rietschel,Andrew McQuillin,Josef Frank,Falk Kiefer,Stefan Schreiber,Wolfgang Lieb,Michael Soyka,Nasser Semmo,Elmar Aigner,Christian Datz,Renate Schmelz,Stefan Brückner,Sebastian Zeissig,Anna-Magdalena Stephan,Norbert Wodarz,Jacques Devière,Nicolas Clumeck,Christoph Sarrazin,Frank Lammert,Thierry Gustot,Pierre Deltenre,Pierre Deltenre,Henry Völzke,Markus M. Lerch,Julia Mayerle,Florian Eyer,Clemens Schafmayer,Sven Cichon,Markus M. Nöthen,Michael Nothnagel,David Ellinghaus,Klaus Huse,Andre Franke,Steffen Zopf,Claus Hellerbrand,Christophe Moreno,Denis Franchimont,Marsha Y. Morgan,Jochen Hampe +48 more
TL;DR: A genome-wide association study for alcohol-related cirrhosis in individuals of European descent with subsequent validation in two independent European cohorts is performed, suggesting that lipid turnover is important in the pathogenesis of alcohol- related Cirrhosis.