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Showing papers by "University of Hertfordshire published in 2013"


Journal ArticleDOI
TL;DR: Used effectively, with the leadership of an experienced qualitative researcher, the Framework Method is a systematic and flexible approach to analysing qualitative data and is appropriate for use in research teams even where not all members have previous experience of conducting qualitative research.
Abstract: The Framework Method is becoming an increasingly popular approach to the management and analysis of qualitative data in health research. However, there is confusion about its potential application and limitations. The article discusses when it is appropriate to adopt the Framework Method and explains the procedure for using it in multi-disciplinary health research teams, or those that involve clinicians, patients and lay people. The stages of the method are illustrated using examples from a published study. Used effectively, with the leadership of an experienced qualitative researcher, the Framework Method is a systematic and flexible approach to analysing qualitative data and is appropriate for use in research teams even where not all members have previous experience of conducting qualitative research.

5,939 citations


Journal ArticleDOI
TL;DR: This review presents recommended nomenclature for the biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs), a rapidly growing class of natural products.

1,560 citations


Journal ArticleDOI
Natalie M. Batalha1, Natalie M. Batalha2, Jason F. Rowe1, Stephen T. Bryson1, Thomas Barclay1, Christopher J. Burke1, Douglas A. Caldwell1, Jessie L. Christiansen1, Fergal Mullally1, Susan E. Thompson1, Timothy M. Brown3, Andrea K. Dupree4, Daniel C. Fabrycky5, Eric B. Ford6, Jonathan J. Fortney5, Ronald L. Gilliland7, Howard Isaacson8, David W. Latham4, Geoffrey W. Marcy8, Samuel N. Quinn4, Samuel N. Quinn9, Darin Ragozzine4, Avi Shporer3, William J. Borucki1, David R. Ciardi10, Thomas N. Gautier10, Michael R. Haas1, Jon M. Jenkins1, David G. Koch1, Jack J. Lissauer1, William Rapin1, Gibor Basri8, Alan P. Boss11, Lars A. Buchhave12, Joshua A. Carter4, David Charbonneau4, Joergen Christensen-Dalsgaard13, Bruce D. Clarke10, William D. Cochran14, Brice-Olivier Demory15, Jean-Michel Desert4, Edna DeVore16, Laurance R. Doyle16, Gilbert A. Esquerdo4, Mark E. Everett, Francois Fressin4, John C. Geary4, Forrest R. Girouard1, Alan Gould17, Jennifer R. Hall1, Matthew J. Holman4, Andrew W. Howard8, Steve B. Howell1, Khadeejah A. Ibrahim1, Karen Kinemuchi1, Hans Kjeldsen13, Todd C. Klaus1, Jie Li1, Philip W. Lucas18, Søren Meibom4, Robert L. Morris1, Andrej Prsa19, Elisa V. Quintana1, Dwight T. Sanderfer1, Dimitar Sasselov4, Shawn Seader1, Jeffrey C. Smith1, Jason H. Steffen20, Martin Still1, Martin C. Stumpe1, Jill Tarter16, Peter Tenenbaum1, Guillermo Torres4, Joseph D. Twicken1, Kamal Uddin1, Jeffrey Van Cleve1, Lucianne M. Walkowicz21, William F. Welsh22 
TL;DR: In this paper, the authors verified nearly 5000 periodic transit-like signals against astrophysical and instrumental false positives yielding 1108 viable new transiting planet candidates, bringing the total count up to over 2300.
Abstract: New transiting planet candidates are identified in 16 months (2009 May-2010 September) of data from the Kepler spacecraft. Nearly 5000 periodic transit-like signals are vetted against astrophysical and instrumental false positives yielding 1108 viable new planet candidates, bringing the total count up to over 2300. Improved vetting metrics are employed, contributing to higher catalog reliability. Most notable is the noise-weighted robust averaging of multi-quarter photo-center offsets derived from difference image analysis that identifies likely background eclipsing binaries. Twenty-two months of photometry are used for the purpose of characterizing each of the candidates. Ephemerides (transit epoch, T_0, and orbital period, P) are tabulated as well as the products of light curve modeling: reduced radius (R_P/R_★), reduced semimajor axis (d/R_★), and impact parameter (b). The largest fractional increases are seen for the smallest planet candidates (201% for candidates smaller than 2 R_⊕ compared to 53% for candidates larger than 2 R_⊕) and those at longer orbital periods (124% for candidates outside of 50 day orbits versus 86% for candidates inside of 50 day orbits). The gains are larger than expected from increasing the observing window from 13 months (Quarters 1-5) to 16 months (Quarters 1-6) even in regions of parameter space where one would have expected the previous catalogs to be complete. Analyses of planet frequencies based on previous catalogs will be affected by such incompleteness. The fraction of all planet candidate host stars with multiple candidates has grown from 17% to 20%, and the paucity of short-period giant planets in multiple systems is still evident. The progression toward smaller planets at longer orbital periods with each new catalog release suggests that Earth-size planets in the habitable zone are forthcoming if, indeed, such planets are abundant.

1,271 citations


Journal ArticleDOI
TL;DR: In this article, the authors review the recent results of the nucleosynthesis yields of mainly massive stars for a wide range of stellar masses, metallicities, and explosion energies, and provide yields tables and examine how those yields are affected by some hydrodynamical effe...
Abstract: After the Big Bang, production of heavy elements in the early Universe takes place starting from the formation of the first stars, their evolution, and explosion. The first supernova explosions have strong dynamical, thermal, and chemical feedback on the formation of subsequent stars and evolution of galaxies. However, the nature of the Universe's first stars and supernova explosions has not been well clarified. The signature of the nucleosynthesis yields of the first stars can be seen in the elemental abundance patterns observed in extremely metal-poor stars. Interestingly, those patterns show some peculiarities relative to the solar abundance pattern, which should provide important clues to understanding the nature of early generations of stars. We thus review the recent results of the nucleosynthesis yields of mainly massive stars for a wide range of stellar masses, metallicities, and explosion energies. We also provide yields tables and examine how those yields are affected by some hydrodynamical effe...

878 citations


Journal ArticleDOI
B. S. Acharya1, Marcos Daniel Actis2, T. Aghajani3, G. Agnetta4  +979 moreInstitutions (122)
TL;DR: The Cherenkov Telescope Array (CTA) as discussed by the authors is a very high-energy (VHE) gamma ray observatory with an international collaboration with more than 1000 members from 27 countries in Europe, Asia, Africa and North and South America.

701 citations


Journal ArticleDOI
TL;DR: In this paper, the authors compare molecular gas traced by CO (2-1) maps from the HERACLES survey, with tracers of the recent star formation rate (SFR) across 30 nearby disk galaxies.
Abstract: We compare molecular gas traced by ^(12)CO (2-1) maps from the HERACLES survey, with tracers of the recent star formation rate (SFR) across 30 nearby disk galaxies. We demonstrate a first-order linear correspondence between Σ_(mol) and Σ_(SFR) but also find important second-order systematic variations in the apparent molecular gas depletion time, τ_(dep)^(mol) = ∑_(mol)/∑_(SFR). At the 1 kpc common resolution of HERACLES, CO emission correlates closely with many tracers of the recent SFR. Weighting each line of sight equally, using a fixed α_(CO) equivalent to the Milky Way value, our data yield a molecular gas depletion time, τ_(dep)^(mol)= ∑_(mol)∑_(SFR) ≈ 2.2 Gyr with 0.3 dex 1σ scatter, in very good agreement with recent literature data. We apply a forward-modeling approach to constrain the power-law index, N, that relates the SFR surface density and the molecular gas surface density, ∑_(SFR) ∝ ∑_(mol)^N. We find N = 1 ± 0.15 for our full data set with some scatter from galaxy to galaxy. This also agrees with recent work, but we caution that a power-law treatment oversimplifies the topic given that we observe correlations between τ_(dep)^(mol) and other local and global quantities. The strongest of these are a decreased τ_(dep)^(mol) in low-mass, low-metallicity galaxies and a correlation of the kpc-scale τ_(dep)^(mol) with dust-to-gas ratio, D/G. These correlations can be explained by a CO-to-H_2 conversion factor (α_(CO)) that depends on dust shielding, and thus D/G, in the theoretically expected way. This is not a unique interpretation, but external evidence of conversion factor variations makes this the most conservative explanation of the strongest observed τ_(dep)^(mol) trends. After applying a D/G-dependent α_(CO), some weak correlations between τ_(dep)^(mol) and local conditions persist. In particular, we observe lower τ_(dep)^(mol) and enhanced CO excitation associated with nuclear gas concentrations in a subset of our targets. These appear to reflect real enhancements in the rate of star formation per unit gas, and although the distribution of τ_(dep) does not appear bimodal in galaxy centers, τ_(dep) does appear multivalued at fixed Σ_(H2), supporting the idea of "disk" and "starburst" modes driven by other environmental parameters.

656 citations


Journal ArticleDOI
TL;DR: Cappellari et al. as mentioned in this paper constructed detailed axisymmetric dynamical models (Jeans Anisotropic MGE), which allow for orbital anisotropy, include a dark matter halo and reproduce in detail both the galaxy images and the high-quality integral-field stellar kinematics out to about 1R(e), the projected half-light radius.
Abstract: We study the volume-limited and nearly mass-selected (stellar mass M-stars greater than or similar to 6 x 10(9) M circle dot) ATLAS(3D) sample of 260 early-type galaxies (ETGs, ellipticals Es and lenticulars S0s). We construct detailed axisymmetric dynamical models (Jeans Anisotropic MGE), which allow for orbital anisotropy, include a dark matter halo and reproduce in detail both the galaxy images and the high-quality integral-field stellar kinematics out to about 1R(e), the projected half-light radius. We derive accurate total mass-to-light ratios (M/L)(e) and dark matter fractions f(DM), within a sphere of radius centred on the galaxies. We also measure the stellar (M/L)(stars) and derive a median dark matter fraction f(DM) = 13 per cent in our sample. We infer masses M-JAM equivalent to L x (M/L)(e) approximate to 2 x M-1/2, where M-1/2 is the total mass within a sphere enclosing half of the galaxy light. We find that the thin two-dimensional subset spanned by galaxies in the (M-JAM, sigma(e), R-e(maj)) coordinates system, which we call the Mass Plane (MP) has an observed rms scatter of 19 per cent, which implies an intrinsic one of 11 per cent. Here, is the major axis of an isophote enclosing half of the observed galaxy light, while Sigma(e) is measured within that isophote. The MP satisfies the scalar virial relation M-JAM proportional to sigma R-2(e)e(maj) within our tight errors. This show that the larger scatter in the Fundamental Plane (FP) (L, Sigma(e), R-e) is due to stellar population effects [including trends in the stellar initial mass function (IMF)]. It confirms that the FP deviation from the virial exponents is due to a genuine (M/L)(e) variation. However, the details of how both R-e and Sigma(e) are determined are critical in defining the precise deviation from the virial exponents. The main uncertainty in masses or M/L estimates using the scalar virial relation is in the measurement of R-e. This problem is already relevant for nearby galaxies and may cause significant biases in virial mass and size determinations at high redshift. Dynamical models can eliminate these problems. We revisit the (M/L)(e)-Sigma(e) relation, which describes most of the deviations between the MP and the FP. The best-fitting relation is (M/L)(e) sigma(0.72)(e) (r band). It provides an upper limit to any systematic increase of the IMF mass normalization with Sigma(e). The correlation is more shallow and has smaller scatter for slow rotating systems or for galaxies in Virgo. For the latter, when using the best distance estimates, we observe a scatter in (M/L)(e) of 11 per cent, and infer an intrinsic one of 8 per cent. We perform an accurate empirical study of the link between Sigma(e) and the galaxies circular velocity V-circ within 1R(e) (where stars dominate) and find the relation max (V-circ) approximate to 1.76 x Sigma(e), which has an observed scatter of 7 per cent. The accurate parameters described in this paper are used in the companion Paper XX (Cappellari et al.) of this series to explore the variation of global galaxy properties, including the IMF, on the projections of the MP.

629 citations


Journal ArticleDOI
TL;DR: In this article, the authors derived accurate total mass-to-light ratios (M/L) approximate to (m/L)(r = R-e) within a sphere of radius r = r-e centred on the galaxy, as well as stellar (M /L)(stars) (with the dark matter removed) for the volume-limited and nearly mass-selected (stellar mass M-star greater than or similar to 6 x 10(9) M-circle dot) ATLAS(3D) sample of 260 early-type galaxies (ETGs
Abstract: In the companion Paper XV of this series, we derive accurate total mass-to-light ratios (M/L)(JAM) approximate to (M/L)(r = R-e) within a sphere of radius r = R-e centred on the galaxy, as well as stellar (M/L)(stars) (with the dark matter removed) for the volume-limited and nearly mass-selected (stellar mass M-star greater than or similar to 6 x 10(9) M-circle dot) ATLAS(3D) sample of 260 early-type galaxies (ETGs, ellipticals Es and lenticulars S0s). Here, we use those parameters to study the two orthogonal projections (M-JAM, sigma(e)) and (M-JAM, R-e(maj)) of the thin Mass Plane (MP) (M-JAM, sigma(e), R-e(maj)) which describes the distribution of the galaxy population, where M-JAM = L x (M/L)(JAM) approximate to M-star. The distribution of galaxy properties on both projections of the MP is characterized by: (i) the same zone of exclusion (ZOE), which can be transformed from one projection to the other using the scalar virial equation. The ZOE is roughly described by two power laws, joined by a break at a characteristic mass M-JAM approximate to 3 x 10(10) M-circle dot, which corresponds to the minimum R-e and maximum stellar density. This results in a break in the mean M-JAM-sigma(e) relation with trends M-JAM proportional to sigma(2.3)(e) and M-JAM proportional to sigma(4.7)(e) at small and large sigma(e), respectively; (ii) a characteristic mass M-JAM approximate to 2 x 10(11) M-circle dot which separates a population dominated by flat fast rotator with discs and spiral galaxies at lower masses, from one dominated by quite round slow rotators at larger masses; (iii) below that mass the distribution of ETGs' properties on the two projections of the MP tends to be constant along lines of roughly constant sigma(e), or equivalently along lines with R-e(maj) proportional to M-JAM, respectively (or even better parallel to the ZOE: R-maj(e) proportional to M-JAM(0.75)); (iv) it forms a continuous and parallel sequence with the distribution of spiral galaxies; (v) at even lower masses, the distribution of fast-rotator ETGs and late spirals naturally extends to that of dwarf ETGs (Sph) and dwarf irregulars (Im), respectively. We use dynamical models to analyse our kinematic maps. We show that Sigma(e) traces the bulge fraction, which appears to be the main driver for the observed trends in the dynamical (M/L)(JAM) and in indicators of the (M/L)(pop) of the stellar population like H beta and colour, as well as in the molecular gas fraction. A similar variation along contours of Sigma(e) is also observed for the mass normalization of the stellar initial mass function (IMF), which was recently shown to vary systematically within the ETGs' population. Our preferred relation has the form log(10)[(M/L)(stars)/(M/L)(Salp)] = a + b x log(10)(sigma(e)/130 km s(-1)) with a = -0.12 +/- 0.01 and b = 0.35 +/- 0.06. Unless there are major flaws in all stellar population models, this trend implies a transition of the mean IMF from Kroupa to Salpeter in the interval log(10)(sigma(e)/km s(-1)) approximate to 1.9-2.5 (or sigma e approximate to 90-290 km s-1), with a smooth variation in between, consistently with what was shown in Cappellari et al. The observed d205 (or sigma e istribution of galaxy properties on the MP provides a clean and novel view for a number of previously reported trends, which constitute special two-dimensional projections of the more general four-dimensional parameters trends on the MP. We interpret it as due to a combination of two main effects: (i) an increase of the bulge fraction, which increases Sigma(e), decreases R-e, and greatly enhance the likelihood for a galaxy to have its star formation quenched, and (ii) dry merging, increasing galaxy mass and R-e by moving galaxies along lines of roughly constant Sigma(e) (or steeper), while leaving the population nearly unchanged.

616 citations


Journal ArticleDOI
TL;DR: In this paper, the authors presented a large-scale spatial resolution map of the CO-to-H$2}$ conversion factor and dust-togas ratio (DGR) in 26 nearby, star-forming galaxies.
Abstract: We present ~{}kiloparsec spatial resolution maps of the CO-to-H$_{2}$ conversion factor ({$α$}$_{CO}$) and dust-to-gas ratio (DGR) in 26 nearby, star-forming galaxies. We have simultaneously solved for {$α$}$_{CO}$ and the DGR by assuming that the DGR is approximately constant on kiloparsec scales. With this assumption, we can combine maps of dust mass surface density, CO-integrated intensity, and H I column density to solve for both {$α$}$_{CO}$ and the DGR with no assumptions about their value or dependence on metallicity or other parameters. Such a study has just become possible with the availability of high-resolution far-IR maps from the Herschel key program KINGFISH, $^{12}$CO J = (2-1) maps from the IRAM 30 m large program HERACLES, and H I 21 cm line maps from THINGS. We use a fixed ratio between the (2-1) and (1-0) lines to present our {$α$}$_{CO}$ results on the more typically used $^{12}$CO J = (1-0) scale and show using literature measurements that variations in the line ratio do not affect our results. In total, we derive 782 individual solutions for {$α$}$_{CO}$ and the DGR. On average, {$α$}$_{CO}$ = 3.1 M $_{☉}$ pc$^{–2}$ (K km s$^{–1}$)$^{–1}$ for our sample with a standard deviation of 0.3 dex. Within galaxies, we observe a generally flat profile of {$α$}$_{CO}$ as a function of galactocentric radius. However, most galaxies exhibit a lower {$α$}$_{CO}$ value in the central kiloparsec{mdash}a factor of ~{}2 below the galaxy mean, on average. In some cases, the central {$α$}$_{CO}$ value can be factors of 5-10 below the standard Milky Way (MW) value of {$α$}$_{CO, MW}$ = 4.4 M $_{☉}$ pc$^{–2}$ (K km s$^{–1}$)$^{–1}$. While for {$α$}$_{CO}$ we find only weak correlations with metallicity, the DGR is well-correlated with metallicity, with an approximately linear slope. Finally, we present several recommendations for choosing an appropriate {$α$}$_{CO}$ for studies of nearby galaxies.

533 citations


Journal ArticleDOI
TL;DR: Galaxy Zoo 2 (GZ2) as discussed by the authors is a citizen science project with more than 16 million morphological classifications of 304 122 galaxies drawn from the Sloan Digital Sky Survey (SDSS).
Abstract: We present the data release for Galaxy Zoo 2 (GZ2), a citizen science project with more than 16 million morphological classifications of 304 122 galaxies drawn from the Sloan Digital Sky Survey (SDSS). Morphology is a powerful probe for quantifying a galaxy's dynamical history; however, automatic classifications of morphology (either by computer analysis of images or by using other physical parameters as proxies) still have drawbacks when compared to visual inspection. The large number of images available in current surveys makes visual inspection of each galaxy impractical for individual astronomers. GZ2 uses classifications from volunteer citizen scientists to measure morphologies for all galaxies in the DR7 Legacy survey with mr > 17, in addition to deeper images from SDSS Stripe 82. While the original GZ2 project identified galaxies as early-types, late-types or mergers, GZ2 measures finer morphological features. These include bars, bulges and the shapes of edge-on disks, as well as quantifying the relative strengths of galactic bulges and spiral arms. This paper presents the full public data release for the project, including measures of accuracy and bias. The majority (≳90 per cent) of GZ2 classifications agree with those made by professional astronomers, especially for morphological T-types, strong bars and arm curvature. Both the raw and reduced data products can be obtained in electronic format at http://data.galaxyzoo.org.

532 citations


Journal ArticleDOI
Carlotta Gruppioni1, Francesca Pozzi2, Giulia Rodighiero3, Ivan Delvecchio2, S. Berta4, Lucia Pozzetti1, G. Zamorani1, P. Andreani, Alessandro Cimatti2, O. Ilbert5, E. Le Floc'h, Dieter Lutz4, Benjamin Magnelli4, Lucia Marchetti6, Lucia Marchetti3, Pierluigi Monaco7, Raanan Nordon4, Seb Oliver8, P. Popesso4, L. Riguccini, Isaac Roseboom9, Isaac Roseboom8, David J. Rosario4, Mark Sargent, Mattia Vaccari3, Mattia Vaccari10, Bruno Altieri, H. Aussel, Ángel Bongiovanni11, J. Cepa11, Emanuele Daddi, H. Dominguez-Sanchez1, H. Dominguez-Sanchez11, D. Elbaz, N. M. Foerster Schreiber4, R. Genzel4, Alvaro Iribarrem12, M. Magliocchetti1, Roberto Maiolino13, Albrecht Poglitsch4, A. M. Pérez García, M. Sánchez-Portal, Eckhard Sturm4, Linda J. Tacconi4, Ivan Valtchanov, Alexandre Amblard14, V. Arumugam9, M. Bethermin, James J. Bock15, James J. Bock16, A. Boselli5, V. Buat5, Denis Burgarella5, N. Castro-Rodríguez17, N. Castro-Rodríguez11, Antonio Cava18, P. Chanial, David L. Clements19, A. Conley20, Asantha Cooray21, Asantha Cooray16, C. D. Dowell15, C. D. Dowell16, Eli Dwek22, Stephen Anthony Eales23, Alberto Franceschini3, Jason Glenn20, Matthew Joseph Griffin23, Evanthia Hatziminaoglou, Edo Ibar24, K. G. Isaak25, Rob Ivison9, Rob Ivison24, Guilaine Lagache26, Louis Levenson16, Louis Levenson15, Nanyao Y. Lu16, S. C. Madden, Bruno Maffei27, G. Mainetti3, H. T. Nguyen15, H. T. Nguyen16, B. O'Halloran19, M. J. Page28, P. Panuzzo, Andreas Papageorgiou23, Chris Pearson29, Chris Pearson30, Ismael Perez-Fournon17, Ismael Perez-Fournon11, Michael Pohlen23, Dimitra Rigopoulou31, Dimitra Rigopoulou30, Michael Rowan-Robinson19, Benjamin L. Schulz16, Douglas Scott32, Nick Seymour33, Nick Seymour28, D. L. Shupe16, Anthony J. Smith8, Jamie Stevens34, M. Symeonidis28, Markos Trichas35, K. E. Tugwell28, L. Vigroux36, Lian-Tao Wang8, G. Wright24, C. K. Xu16, Michael Zemcov15, Michael Zemcov16, S. Bardelli1, M. Carollo37, Thierry Contini38, O. Le Fevre5, Simon J. Lilly37, Vincenzo Mainieri, Alvio Renzini1, Marco Scodeggio1, E. Zucca1 
TL;DR: In this article, the authors exploit the deep and extended far-IR data sets (at 70, 100 and 160 μm) of the GPS PACS Evolutionary Probe (PEP) Survey, in combination with the Herschel Multi-tiered Extragalactic Survey data at 250, 350 and 500 μm, to derive the evolution of the rest-frame 35-, 60-, 90- and total infrared luminosity functions (LFs) up to z ∼ 4.
Abstract: We exploit the deep and extended far-IR data sets (at 70, 100 and 160 μm) of the Herschel Guaranteed Time Observation (GTO) PACS Evolutionary Probe (PEP) Survey, in combination with the Herschel Multi-tiered Extragalactic Survey data at 250, 350 and 500 μm, to derive the evolution of the rest-frame 35-, 60-, 90- and total infrared (IR) luminosity functions (LFs) up to z ∼ 4. We detect very strong luminosity evolution for the total IR LF (LIR ∝ (1 + z)3.55 ± 0.10 up to z ∼ 2, and ∝ (1 + z)1.62 ± 0.51 at 2 < z ≲ 4) combined with a density evolution (∝(1 + z)−0.57 ± 0.22 up to z ∼ 1 and ∝ (1 + z)−3.92 ± 0.34 at 1 < z ≲ 4). In agreement with previous findings, the IR luminosity density (ρIR) increases steeply to z ∼ 1, then flattens between z ∼ 1 and z ∼ 3 to decrease at z ≳ 3. Galaxies with different spectral energy distributions, masses and specific star formation rates (SFRs) evolve in very different ways and this large and deep statistical sample is the first one allowing us to separately study the different evolutionary behaviours of the individual IR populations contributing to ρIR. Galaxies occupying the well-established SFR–stellar mass main sequence (MS) are found to dominate both the total IR LF and ρIR at all redshifts, with the contribution from off-MS sources (≥0.6 dex above MS) being nearly constant (∼20 per cent of the total ρIR) and showing no significant signs of increase with increasing z over the whole 0.8 < z < 2.2 range. Sources with mass in the range 10 ≤ log(M/M⊙) ≤ 11 are found to dominate the total IR LF, with more massive galaxies prevailing at the bright end of the high-z (≳2) LF. A two-fold evolutionary scheme for IR galaxies is envisaged: on the one hand, a starburst-dominated phase in which the Super Massive Black Holes (SMBH) grows and is obscured by dust (possibly triggered by a major merging event), is followed by an AGN-dominated phase, then evolving towards a local elliptical. On the other hand, moderately star-forming galaxies containing a low-luminosity AGN have various properties suggesting they are good candidates for systems in a transition phase preceding the formation of steady spiral galaxies.

Journal ArticleDOI
TL;DR: The aim of the present study was to investigate the association between diabetes and the risk of all type dementia (ATD), Alzheimer's disease (AD) and vascular dementia (VaD).
Abstract: Aims/Introduction The aim of the present study was to investigate the association between diabetes and the risk of all type dementia (ATD), Alzheimer's disease (AD) and vascular dementia (VaD). Materials and Methods Prospective observational studies describing the incidence of ATD, AD and VaD in patients with diabetes mellitus were extracted from PubMed, EMBASE and other databases up to January 2012. Pooled relative risk (RR) estimates and 95% confidence intervals (CIs) were calculated using the random-effects model. Subgroup analyses and sensitivity analysis were also carried out. Results A total of 28 studies contributed to the analysis. Pooled RR of developing ATD (n = 20) was 1.73 (1.65–1.82, I2 = 71.2%), AD (n = 20) was 1.56 (1.41–1.73, I2 = 9.8%) and VaD (n = 13) was 2.27 (1.94–2.66, I2 = 0%) in patients with diabetes mellitus. Higher and medium quality studies did not show any significant difference for pooled RR for ATD, AD or VaD. Sensitivity analyses showed robustness of pooled RR among ATD, AD and VaD, showing no single study had a major impact on pooled RR. Conclusions The results showed a 73% increased risk of ATD, 56% increase of AD and 127% increase of VaD in diabetes patients.

Journal ArticleDOI
TL;DR: In this article, a procedure is developed for constructing deformations of integrable σ-models which are themselves classically integrably this article and the actions correspond to a deformation of the target space geometry and include a torsion term.
Abstract: A procedure is developed for constructing deformations of integrable σ-models which are themselves classically integrable. When applied to the principal chiral model on any compact Lie group F, one recovers the Yang-Baxter σ-model introduced a few years ago by C. Klimyc´ok. In the case of the symmetric space σ-model on F/G we obtain a new one-parameter family of integrable σ-models. The actions of these models correspond to a deformation of the target space geometry and include a torsion term. An interesting feature of the construction is the q-deformation of the symmetry corresponding to left multiplication in the original models, which becomes replaced by a classical q-deformed Poisson-Hopf algebra. Another noteworthy aspect of the deformation in the coset σ-model case is that it interpolates between a compact and a non-compact symmetric space. This is exemplified in the case of the SU(2)/U(1) coset σ-model which interpolates all the way to the SU(1,1)/U(1) coset σ-model.

Journal ArticleDOI
TL;DR: Activation likelihood estimation (ALE) meta-analyses were used to examine the neural correlates of prediction error in reinforcement learning, finding that reward prediction errors were observed primarily in the striatum while aversive predictionerrors were found more widely including insula and habenula.

Journal ArticleDOI
TL;DR: In this article, a homogeneous chemical abundance analysis of 16 elements in 190 metal-poor Galactic halo stars (38 program and 152 literature objects) is presented, of which 86 are extremely metal poor, [Fe/H] {<=} -3.0.
Abstract: We present a homogeneous chemical abundance analysis of 16 elements in 190 metal-poor Galactic halo stars (38 program and 152 literature objects). The sample includes 171 stars with [Fe/H] {<=} -2.5, of which 86 are extremely metal poor, [Fe/H] {<=} -3.0. Our program stars include 10 new objects with [Fe/H] {<=} -3.5. We identify a sample of 'normal' metal-poor stars and measure the trends between [X/Fe] and [Fe/H], as well as the dispersion about the mean trend for this sample. Using this mean trend, we identify objects that are chemically peculiar relative to 'normal' stars at the same metallicity. These chemically unusual stars include CEMP-no objects, one star with high [Si/Fe], another with high [Ba/Sr], and one with unusually low [X/Fe] for all elements heavier than Na. The Sr and Ba abundances indicate that there may be two nucleosynthetic processes at lowest metallicity that are distinct from the main r-process. Finally, for many elements, we find a significant trend between [X/Fe] versus T {sub eff}, which likely reflects non-LTE and/or three-dimensional effects. Such trends demonstrate that care must be exercised when using abundance measurements in metal-poor stars to constrain chemical evolution and/or nucleosynthesis predictions.

Journal ArticleDOI
TL;DR: A bifactor structure provides the most acceptable empirical explanation for the HADS correlation structure and it is recommended it is best used as a measure of general distress.

Journal ArticleDOI
TL;DR: In this paper, the authors apply comprehensive gas-dynamical models that include the propagation of emission-line profiles through the telescope and spectrograph optics to new Space Telescope Imaging Spectrograph observations from the Hubble Space Telescope, and find that a small amount of velocity dispersion internal to the gas disk is required to match the observed line widths.
Abstract: The supermassive black hole of M87 is one of the most massive black holes known and has been the subject of several stellar and gas-dynamical mass measurements; however, the most recent revision to the stellar-dynamical black hole mass measurement is a factor of about two larger than the previous gas-dynamical determinations. Here, we apply comprehensive gas-dynamical models that include the propagation of emission-line profiles through the telescope and spectrograph optics to new Space Telescope Imaging Spectrograph observations from the Hubble Space Telescope. Unlike the previous gas-dynamical studies of M87, we map out the complete kinematic structure of the emission-line disk within ~40 pc from the nucleus, and find that a small amount of velocity dispersion internal to the gas disk is required to match the observed line widths. We examine a scenario in which the intrinsic velocity dispersion provides dynamical support to the disk, and determine that the inferred black hole mass increases by only 6%. Incorporating this effect into the error budget, we ultimately measure a mass of (68% confidence). Our gas-dynamical black hole mass continues to differ from the most recent stellar-dynamical mass by a factor of two, underscoring the need for carrying out more cross-checks between the two main black hole mass measurement methods.

Journal ArticleDOI
TL;DR: In this paper, the authors reported the direct-imaging discovery of a Jovian exoplanet around the Sun-like star GJ 504, detected as part of the SEEDS survey.
Abstract: Several exoplanets have recently been imaged at wide separations of >10?AU from their parent stars. These span a limited range of ages ( 0.5?mag), implying thick cloud covers. Furthermore, substantial model uncertainties exist at these young ages due to the unknown initial conditions at formation, which can lead to an order of magnitude of uncertainty in the modeled planet mass. Here, we report the direct-imaging discovery of a Jovian exoplanet around the Sun-like star GJ 504, detected as part of the SEEDS survey. The system is older than all other known directly imaged planets; as a result, its estimated mass remains in the planetary regime independent of uncertainties related to choices of initial conditions in the exoplanet modeling. Using the most common exoplanet cooling model, and given the system age of 160?Myr, GJ 504b has an estimated mass of 4 Jupiter masses, among the lowest of directly imaged planets. Its projected separation of 43.5?AU exceeds the typical outer boundary of ~30?AU predicted for the core accretion mechanism. GJ 504b is also significantly cooler (510 K) and has a bluer color (J ? H = ?0.23?mag) than previously imaged exoplanets, suggesting a largely cloud-free atmosphere accessible to spectroscopic characterization. Thus, it has the potential of providing novel insights into the origins of giant planets as well as their atmospheric properties.

Journal ArticleDOI
TL;DR: Whole tumor analysis appears more representative of tumor heterogeneity, and Kaplan-Meier analysis demonstrated better of E and U for whole tumor analysis for 5-year overall survival.

Journal ArticleDOI
TL;DR: The results suggest that physical models may hold a significant advantage over alternative learning resources in enhancing visuospatial and 3D understanding of complex anatomical architecture, and that 3D computer models have significant limitations with regards to 3D learning.
Abstract: Three-dimensional (3D) information plays an important part in medical and veterinary education Appreciating complex 3D spatial relationships requires a strong foundational understanding of anatomy and mental 3D visualization skills Novel learning resources have been introduced to anatomy training to achieve this Objective evaluation of their comparative efficacies remains scarce in the literature This study developed and evaluated the use of a physical model in demonstrating the complex spatial relationships of the equine foot It was hypothesized that the newly developed physical model would be more effective for students to learn magnetic resonance imaging (MRI) anatomy of the foot than textbooks or computer-based 3D models Third year veterinary medicine students were randomly assigned to one of three teaching aid groups (physical model; textbooks; 3D computer model) The comparative efficacies of the three teaching aids were assessed through students' abilities to identify anatomical structures on MR images Overall mean MRI assessment scores were significantly higher in students utilizing the physical model (8639%) compared with students using textbooks (6261%) and the 3D computer model (6368%) (P < 0001), with no significant difference between the textbook and 3D computer model groups (P = 0685) Student feedback was also more positive in the physical model group compared with both the textbook and 3D computer model groups Our results suggest that physical models may hold a significant advantage over alternative learning resources in enhancing visuospatial and 3D understanding of complex anatomical architecture, and that 3D computer models have significant limitations with regards to 3D learning Anat Sci Educ 6: 216–224 © 2013 American Association of Anatomists

Journal ArticleDOI
TL;DR: This review provides a presentation of salt and cocrystal selection, from a high throughput screening perspective and then an assessment of counter ion properties, common ion effects and the potential impact on the biopharmaceutical performance of the compound.


Journal ArticleDOI
TL;DR: Using Option Grids made options more visible and clinicians found it easier to undertake shared decision making when these tools were available, and reported a 'handover' effect, where patient involvement in decision making was enhanced.

Proceedings ArticleDOI
28 Jan 2013
TL;DR: The first evaluation iterations have shown the potential of this methodology in terms of adaptation of the robot to the interactant and the resulting influences on engagement, setting the foundation for an ongoing research program that seeks to develop technologies for social robot companions.
Abstract: For robots to interact effectively with human users they must be capable of coordinated, timely behavior in response to social context. The Adaptive Strategies for Sustainable Long-Term Social Interaction (ALIZ-E) project focuses on the design of long-term, adaptive social interaction between robots and child users in real-world settings. In this paper, we report on the iterative approach taken to scientific and technical developments toward this goal: advancing individual technical competencies and integrating them to form an autonomous robotic system for evaluation "in the wild." The first evaluation iterations have shown the potential of this methodology in terms of adaptation of the robot to the interactant and the resulting influences on engagement. This sets the foundation for an ongoing research program that seeks to develop technologies for social robot companions.

Journal ArticleDOI
TL;DR: In this article, the authors presented the first photometric redshift distribution for a large unbiased sample of 870um selected submillimeter galaxies (SMGs) with robust identifications based on observations with the Atacama Large Millimeter Array (ALMA).
Abstract: We present the first photometric redshift distribution for a large unbiased sample of 870um selected submillimeter galaxies (SMGs) with robust identifications based on observations with the Atacama Large Millimeter Array (ALMA). In our analysis we consider 96 SMGs in the Extended Chandra Deep Field South, 77 of which have 4-19 band, optical-near-infrared, photometry. We model the Spectral Energy Distributions (SEDs) for these 77 SMGs, deriving a median photometric redshift of z=2.3+/-0.1. The remaining 19 SMGs have insufficient optical or near-infrared photometry to derive photometric redshifts, but a stacking analysis of IRAC and Herschel observations confirms they are not spurious. Assuming these sources have an absolute H-band magnitude distribution comparable to that of a complete sample of z~1-2 SMGs, we demonstrate that the undetected SMGs lie at higher redshifts, raising the median redshift for SMGs to z=2.5+/-0.2. More critically we show that the proportion of galaxies undergoing an SMG phase at z>3 is 35+/-5% of the total population. We derive a median stellar mass for SMGs of Mstar=(8+/-1)x10^10Mo, but caution that there are significant systematic uncertainties in our stellar mass estimate, up to x5 for individual sources. We compare our sample of SMGs to a volume-limited, morphologically classified sample of ellipticals in the local Universe. Assuming the star formation activity in SMGs has a timescale of ~100Myr we show that their descendants at z~0 would have a space density and M_H distribution which are in good agreement with those of local ellipticals. In addition the inferred mass-weighted ages of the local ellipticals broadly agree with the look-back times of the SMG events. Taken together, these results are consistent with a simple model that identifies SMGs as events that form most of the stars seen in the majority of luminous elliptical galaxies at the present day.

Book
28 Mar 2013
TL;DR: This book provides 32 chapters, written by leading SIA researchers, addressing topics such as: social robotics, embodied conversational agents, affective computing, anthropomorphism, narrative and story-telling, social aspects in multi-agent systems, new technologies for education and therapy, and more.
Abstract: The field of Socially Intelligent Agents (SIA) is a fast growing and increasingly important area that comprises highly active research activities and strongly interdisciplinary approaches. Socially Intelligent Agents, edited by Kerstin Dautenhahn, Alan Bond, Lola Caamero and Bruce Edmonds, emerged from the AAAI Symposium "Socially Intelligent Agents - The Human in the Loop". The book provides 32 chapters, written by leading SIA researchers, addressing topics such as: social robotics, embodied conversational agents, affective computing, anthropomorphism, narrative and story-telling, social aspects in multi-agent systems, new technologies for education and therapy, and more. This breadth of topics covered in Socially Intelligent Agents provides the reader with a comprehensive look at current research activities in the area. Socially Intelligent Agents serves as an excellent reference for a wide readership, e.g. computer scientists, roboticists, web programmers and designers, computer users, cognitive scientists, and other researchers interested in the study of how humans relate to computers and robots, and how these agents in return can relate to humans. This book is also suitable as research material in a variety of advanced level courses, including Applied Artificial Intelligence, Autonomous Agents, Human-Computer Interaction, Situated, Embodied AI.

Journal ArticleDOI
TL;DR: The first data release of the VISTA Deep Extragalactic Observations (VIDEO) survey is described in this article, which is a similar to 12 deg(2) survey in the near-infrared Z, Y, J, H and K-s bands.
Abstract: In this paper, we describe the first data release of the Visible and Infrared Survey Telescope for Astronomy (VISTA) Deep Extragalactic Observations (VIDEO) survey. VIDEO is a similar to 12 deg(2) survey in the near-infrared Z, Y, J, H and K-s bands, specifically designed to enable the evolution of galaxies and large structures to be traced as a function of both epoch and environment from the present day out to z = 4, and active galactic nuclei (AGNs) and the most massive galaxies up to and into the epoch of reionization. With its depth and area, VIDEO will be able to fully explore the period in the Universe where AGN and starburst activity were at their peak and the first galaxy clusters were beginning to virialize. VIDEO therefore offers a unique data set with which to investigate the interplay between AGN, starbursts and environment, and the role of feedback at a time when it was potentially most crucial. We provide data over the VIDEO-XMM3 tile, which also covers the Canada-France-Hawaii Telescope Legacy Survey Deep-1 field (CFHTLS-D1). The released VIDEO data reach a 5 sigma AB-magnitude depth of Z = 25.7, Y = 24.5, J = 24.4, H = 24.1 and Ks = 23.8 in 2 arcsec diameter apertures (the full depth of Y = 24.6 will be reached within the full integration time in future releases). The data are compared to previous surveys over this field and we find good astrometric agreement with the Two Micron All Sky Survey, and source counts in agreement with the recently released UltraVISTA survey data. The addition of the VIDEO data to the CFHTLS-D1 optical data increases the accuracy of photometric redshifts and significantly reduces the fraction of catastrophic outliers over the redshift range 0 \textless z \textless 1 from 5.8 to 3.1 per cent in the absence of an i-band luminosity prior. However, we expect that the main improvement in photometric redshifts will come in the redshift range 1 \textless z \textless 4 due to the sensitivity to the Balmer and 4000 angstrom breaks provided by the near-infrared VISTA filters. All images and catalogues presented in this paper are publicly available through ESO's phase 3 archive and the VISTA Science Archive.

Proceedings ArticleDOI
08 Oct 2013
TL;DR: An improved load balanced algorithm is introduced on the ground of Min-Min algorithm in order to reduce the makespan and increase the resource utilization (LBIMM) and simulation results show that the improved algorithm can lead to significant performance gain and achieve over 20% improvement on both VIP user satisfaction and resource utilization ratio.
Abstract: Cloud computing is emerging as a new paradigm of large-scale distributed computing. In order to utilize the power of cloud computing completely, we need an efficient task scheduling algorithm. The traditional Min-Min algorithm is a simple, efficient algorithm that produces a better schedule that minimizes the total completion time of tasks than other algorithms in the literature [7]. However the biggest drawback of it is load imbalanced, which is one of the central issues for cloud providers. In this paper, an improved load balanced algorithm is introduced on the ground of Min-Min algorithm in order to reduce the makespan and increase the resource utilization (LBIMM). At the same time, Cloud providers offer computer resources to users on a pay-per-use base. In order to accommodate the demands of different users, they may offer different levels of quality for services. Then the cost per resource unit depends on the services selected by the user. In return, the user receives guarantees regarding the provided resources. To observe the promised guarantees, user-priority was considered in our proposed PA-LBIMM so that user's demand could be satisfied more completely. At last, the introduced algorithm is simulated using Matlab toolbox. The simulation results show that the improved algorithm can lead to significant performance gain and achieve over 20% improvement on both VIP user satisfaction and resource utilization ratio.

Journal ArticleDOI
TL;DR: In this article, the carbon-normal and carbon-rich populations of Galactic halo stars having [Fe/H] {approx} + 1.5 were discussed and the light elements Na, Mg, and Al were enhanced relative to Fe in half the sample; and for Z > 20 (Ca) there is little evidence for enhancements relative to solar values.
Abstract: We discuss the carbon-normal and carbon-rich populations of Galactic halo stars having [Fe/H] {approx} +1.5); the light elements Na, Mg, and Al are enhanced relative to Fe in half the sample; and for Z > 20 (Ca) there is little evidence for enhancements relative to solar values. These results are best explained in terms of the admixing and processing of material from H-burning and He-burning regions as achieved by nucleosynthesis in zero-heavy-element models in the literature of 'mixing and fallback' supernovae (SNe); of rotating, massive, and intermediate-mass stars; and of Type II SNe with relativistic jets. The available (limited) radial velocities offer little support for the C-rich stars with [Fe/H] < -3.1 being binary. More data are required before one could conclude that binarity is key to an understanding of this population. We suggest that the C-rich and C-normal populations result from two different gas cooling channels in the very early universe of materialmore » that formed the progenitors of the two populations. The first was cooling by fine-structure line transitions of C II and O I (to form the C-rich population); the second, while not well defined (perhaps dust-induced cooling?), led to the C-normal group. In this scenario, the C-rich population contains the oldest stars currently observed.« less

Journal ArticleDOI
TL;DR: The main part of the review focuses on the nuclear uncertainties involved in the determination of the astrophysical reaction rates required for the extended reaction networks used in nucleosynthesis studies.
Abstract: A small number of naturally occurring, proton-rich nuclides (the p-nuclei) cannot be made in the s- and r-processes. Their origin is not well understood. Massive stars can produce p-nuclei through photodisintegration of pre-existing intermediate and heavy nuclei. This so-called γ-process requires high stellar plasma temperatures and occurs mainly in explosive O/Ne burning during a core-collapse supernova. Although the γ-process in massive stars has been successful in producing a large range of p-nuclei, significant deficiencies remain. An increasing number of processes and sites has been studied in recent years in search of viable alternatives replacing or supplementing the massive star models. A large number of unstable nuclei, however, with only theoretically predicted reaction rates are included in the reaction network and thus the nuclear input may also bear considerable uncertainties. The current status of astrophysical models, nuclear input and observational constraints is reviewed. After an overview of currently discussed models, the focus is on the possibility to better constrain those models through different means. Meteoritic data not only provide the actual isotopic abundances of the p-nuclei but can also put constraints on the possible contribution of proton-rich nucleosynthesis. The main part of the review focuses on the nuclear uncertainties involved in the determination of the astrophysical reaction rates required for the extended reaction networks used in nucleosynthesis studies. Experimental approaches are discussed together with their necessary connection to theory, which is especially pronounced for reactions with intermediate and heavy nuclei in explosive nuclear burning, even close to stability.