M
Michael O. Woods
Researcher at Memorial University of Newfoundland
Publications - 113
Citations - 5356
Michael O. Woods is an academic researcher from Memorial University of Newfoundland. The author has contributed to research in topics: Colorectal cancer & Cancer. The author has an hindex of 35, co-authored 98 publications receiving 4205 citations. Previous affiliations of Michael O. Woods include BC Cancer Agency & St. John's University.
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Journal ArticleDOI
Improving the stability of 11C–labeled L-methionine with ascorbate
Michael O. Woods,Leo Leung,Kari Frantzen,Jennifer G. Garrick,Zhengxing Zhang,Chengcheng Zhang,Wade English,Don Wilson,Francois Benard,Francois Benard,Kuo-Shyan Lin,Kuo-Shyan Lin +11 more
TL;DR: To minimize oxidation, ascorbate was added to the HPLC eluant, and the resulting HPLC-purified 11C–MET was stable in the final formulation solution without noticeable degradation for up to 1 h after the end of synthesis.
Journal ArticleDOI
Functional informed genome-wide interaction analysis of body mass index, diabetes and colorectal cancer risk.
Zhiyu Xia,Yu Ru Su,Paneen S. Petersen,Lihong Qi,Andre E. Kim,Jane C. Figueiredo,Jane C. Figueiredo,Yi Lin,Hongmei Nan,Lori C. Sakoda,Lori C. Sakoda,Demetrius Albanes,Sonja I. Berndt,Stéphane Bézieau,Stephanie A. Bien,Daniel D. Buchanan,Daniel D. Buchanan,Graham Casey,Andrew T. Chan,Andrew T. Chan,David V. Conti,David A. Drew,Steven Gallinger,W. James Gauderman,Graham G. Giles,Stephen B. Gruber,Marc J. Gunter,Michael Hoffmeister,Mark A. Jenkins,Amit Joshi,Loic Le Marchand,Juan Pablo Lewinger,Li Li,Noralane M. Lindor,Victor Moreno,Neil Murphy,Rami Nassir,Polly A. Newcomb,Polly A. Newcomb,Shuji Ogino,Shuji Ogino,Gad Rennert,Mingyang Song,Xiaoliang Wang,Alicja Wolk,Michael O. Woods,Hermann Brenner,Emily White,Emily White,Martha L. Slattery,Edward Giovannucci,Edward Giovannucci,Jenny Chang-Claude,Jenny Chang-Claude,Paul D.P. Pharoah,Li Hsu,Li Hsu,Peter T. Campbell,Ulrike Peters,Ulrike Peters +59 more
TL;DR: Body mass index (BMI) and diabetes are established risk factors for colorectal cancer (CRC), likely through perturbations in metabolic traits (e.g. insulin resistance and glucose homeostasis).
Journal ArticleDOI
Publisher Correction: Shared heritability and functional enrichment across six solid cancers.
Xia Jiang,Xia Jiang,Hilary K. Finucane,Hilary K. Finucane,Fredrick R. Schumacher,Stephanie L. Schmit,Jonathan Tyrer,Younghun Han,Kyriaki Michailidou,Kyriaki Michailidou,Corina Lesseur,Karoline Kuchenbaecker,Joe Dennis,David V. Conti,Graham Casey,Mia M. Gaudet,Jeroen R. Huyghe,Demetrius Albanes,Melinda C. Aldrich,Angeline S. Andrew,Irene L. Andrulis,Irene L. Andrulis,Hoda Anton-Culver,Antonis C. Antoniou,Natalia Antonenkova,Susanne M. Arnold,Kristan J. Aronson,Banu Arun,Elisa V. Bandera,Rosa B. Barkardottir,Daniel R. Barnes,Jyotsna Batra,Jyotsna Batra,Matthias W. Beckmann,Javier Benitez,Sara Benlloch,Sara Benlloch,Andrew Berchuck,Sonja I. Berndt,Heike Bickeböller,Stephanie A. Bien,Stephanie A. Bien,Carl Blomqvist,Carl Blomqvist,Stefania Boccia,Natalia Bogdanova,Stig E. Bojesen,Stig E. Bojesen,Manjeet K. Bolla,Hiltrud Brauch,Hiltrud Brauch,Hiltrud Brauch,Hermann Brenner,James D. Brenton,Mark N. Brook,Joan Brunet,Hans Brunnström,Daniel D. Buchanan,Daniel D. Buchanan,Barbara Burwinkel,Barbara Burwinkel,Ralf Bützow,Gabriella Cadoni,Trinidad Caldés,Maria A. Caligo,Ian G. Campbell,Ian G. Campbell,Peter T. Campbell,Geraldine Cancel-Tassin,Lisa A. Cannon-Albright,Lisa A. Cannon-Albright,Daniele Campa,Daniele Campa,Neil E. Caporaso,André Lopes Carvalho,Andrew T. Chan,Andrew T. Chan,Jenny Chang-Claude,Stephen J. Chanock,Chu Chen,David C. Christiani,Kathleen Claes,Frank Claessens,Judith A. Clements,Judith A. Clements,J. Margriet Collée,Marcia Cruz Correa,Fergus J. Couch,Angela Cox,Julie M. Cunningham,Cezary Cybulski,Kamila Czene,Mary B. Daly,Anna deFazio,Anna deFazio,Peter Devilee,Orland Diez,Manuela Gago-Dominguez,Jenny L Donovan,Thilo Dörk,Eric J. Duell,Alison M. Dunning,Miriam Dwek,Diana Eccles,Christopher K. Edlund,Digna R. Velez Edwards,Carolina Ellberg,D. Gareth Evans,Peter A. Fasching,Peter A. Fasching,Robert L. Ferris,Triantafillos Liloglou,Jane C. Figueiredo,Jane C. Figueiredo,Olivia Fletcher,Renée T. Fortner,Florentia Fostira,Silvia Franceschi,Eitan Friedman,Eitan Friedman,Steven Gallinger,Steven Gallinger,Steven Gallinger,Patricia A. Ganz,Judy Garber,José A. García-Sáenz,Simon A. Gayther,Simon A. Gayther,Graham G. Giles,Graham G. Giles,Andrew K. Godwin,Mark S. Goldberg,David E. Goldgar,Ellen L. Goode,Marc T. Goodman,Gary E. Goodman,Kjell Grankvist,Mark H. Greene,Henrik Grönberg,Jacek Gronwald,Pascal Guénel,Niclas Håkansson,Per Hall,Ute Hamann,Freddie C. Hamdy,Robert J. Hamilton,Jochen Hampe,Aage Haugen,Florian Heitz,Rolando Herrero,Peter Hillemanns,Michael Hoffmeister,Estrid Høgdall,Yun-Chul Hong,John L. Hopper,Richard S. Houlston,Peter J. Hulick,Peter J. Hulick,David J. Hunter,David G. Huntsman,David G. Huntsman,Gregory Idos,Evgeny N. Imyanitov,Sue A. Ingles,Claudine Isaacs,Anna Jakubowska,Anna Jakubowska,Paul A. James,Mark A. Jenkins,Mattias Johansson,Mikael Johansson,Esther M. John,Amit Joshi,Radka Kaneva,Beth Y. Karlan,Linda E. Kelemen,Tabea Kühl,Kay-Tee Khaw,Elza Khusnutdinova,Elza Khusnutdinova,Adam S. Kibel,Lambertus A. Kiemeney,Jeri Kim,Susanne K. Kjaer,Julia A. Knight,Julia A. Knight,Manolis Kogevinas,Zsofia Kote-Jarai,Stella Koutros,Vessela N. Kristensen,Vessela N. Kristensen,Jolanta Kupryjanczyk,Martin Lacko,Stephan Lam,Diether Lambrechts,Maria Teresa Landi,Philip Lazarus,Nhu D. Le,Eunjung Lee,Flavio Lejbkowicz,Heinz-Josef Lenz,Goska Leslie,Davor Lessel,Jenny Lester,Douglas A. Levine,Douglas A. Levine,Li Li,Christopher I. Li,Annika Lindblom,Noralane M. Lindor,Geoffrey Liu,Fotios Loupakis,Jan Lubinski,Lovise Maehle,Christiane Maier,Arto Mannermaa,Loic Le Marchand,Sara Margolin,Taymaa May,Lesley McGuffog,Alfons Meindl,Pooja Middha,Pooja Middha,Austin Miller,Roger L. Milne,Robert J. MacInnis,Francesmary Modugno,Marco Montagna,Victor Moreno,Kirsten B. Moysich,Lorelei A. Mucci,Kenneth Muir,Kenneth Muir,Anna Marie Mulligan,Anna Marie Mulligan,Katherine L. Nathanson,David E. Neal,David E. Neal,Andy R Ness,Susan L. Neuhausen,Heli Nevanlinna,Polly A. Newcomb,Polly A. Newcomb,Lisa F. Newcomb,Lisa F. Newcomb,Finn Cilius Nielsen,Liene Nikitina-Zake,Børge G. Nordestgaard,Børge G. Nordestgaard,Robert L. Nussbaum,Kenneth Offit,Edith Olah,Ali Amin Al Olama,Olufunmilayo I. Olopade,Andrew F. Olshan,Håkan Olsson,Ana Osorio,Hardev Pandha,Jong Y. Park,Nora Pashayan,Nora Pashayan,Michael T. Parsons,Tanja Pejovic,Kathryn L. Penney,Wilbert H.M. Peters,Catherine M. Phelan,Amanda I. Phipps,Amanda I. Phipps,Dijana Plaseska-Karanfilska,Miranda Pring,Darya Prokofyeva,Paolo Radice,Kari Stefansson,Susan J. Ramus,Susan J. Ramus,Leon Raskin,Gad Rennert,Hedy S. Rennert,Elizabeth J. van Rensburg,Marjorie J. Riggan,Harvey A. Risch,Angela Risch,Angela Risch,Monique J. Roobol,Barry S. Rosenstein,Mary Anne Rossing,Mary Anne Rossing,Kim De Ruyck,Emmanouil Saloustros,Dale P. Sandler,Elinor J. Sawyer,Matthew B. Schabath,Johanna Schleutker,Johanna Schleutker,Johanna Schleutker,Marjanka K. Schmidt,V. Wendy Setiawan,Hongbing Shen,Erin M. Siegel,Weiva Sieh,Christian F. Singer,Martha L. Slattery,Karina Dalsgaard Sørensen,Karina Dalsgaard Sørensen,Melissa C. Southey,Melissa C. Southey,Amanda B. Spurdle,Janet L. Stanford,Janet L. Stanford,Victoria L. Stevens,Sebastian Stintzing,Jennifer Stone,Karin Sundfeldt,Rebecca Sutphen,Anthony J. Swerdlow,Eloiza H. Tajara,Catherine M. Tangen,Adonina Tardón,Jack A. Taylor,M. Dawn Teare,Manuel R. Teixeira,Mary Beth Terry,Kathryn L. Terry,Kathryn L. Terry,Stephen N. Thibodeau,Mads Thomassen,Line Bjørge,Line Bjørge,Marc Tischkowitz,Marc Tischkowitz,Amanda E. Toland,Diana Torres,Diana Torres,Paul A. Townsend,Ruth C. Travis,Nadine Tung,Shelley S. Tworoger,Cornelia M. Ulrich,Cornelia M. Ulrich,Nawaid Usmani,Celine M. Vachon,Els Van Nieuwenhuysen,Ana Vega,Miguel E. Aguado-Barrera,Qin Wang,Penelope M. Webb,Clarice R. Weinberg,Stephanie J. Weinstein,Mark C. Weissler,Jeffrey N. Weitzel,Catharine M L West,Emily White,Emily White,Alice S. Whittemore,H-Erich Wichmann,H-Erich Wichmann,Fredrik Wiklund,Robert Winqvist,Alicja Wolk,Alicja Wolk,Penella J. Woll,Michael O. Woods,Anna H. Wu,Xifeng Wu,Drakoulis Yannoukakos,Wei Zheng,Shanbeh Zienolddiny,Argyrios Ziogas,Kristin K. Zorn,Jacqueline M. Lane,Jacqueline M. Lane,Richa Saxena,Richa Saxena,Duncan Thomas,Rayjean J. Hung,Rayjean J. Hung,Brenda Diergaarde,James McKay,Ulrike Peters,Li Hsu,Montserrat Garcia-Closas,Rosalind A. Eeles,Georgia Chenevix-Trench,Paul Brennan,Christopher A. Haiman,Jacques Simard,Douglas F. Easton,Stephen B. Gruber,Paul D.P. Pharoah,Alkes L. Price,Alkes L. Price,Bogdan Pasaniuc,Christopher I. Amos,Peter Kraft,Sara Lindström,Sara Lindström +395 more
TL;DR: An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Journal ArticleDOI
A Combined Proteomics and Mendelian Randomization Approach to Investigate the Effects of Aspirin-Targeted Proteins on Colorectal Cancer.
Aayah Nounu,Aayah Nounu,Alexander Greenhough,Alexander Greenhough,Kate J. Heesom,Rebecca C Richmond,Jie Zheng,Stephanie J. Weinstein,Demetrius Albanes,John A. Baron,John L. Hopper,John L. Hopper,Jane C. Figueiredo,Jane C. Figueiredo,Polly A. Newcomb,Polly A. Newcomb,Noralane M. Lindor,Graham Casey,Elizabeth A. Platz,Loic Le Marchand,Cornelia M. Ulrich,Christopher I. Li,Fränzel J.B. van Duijnhoven,Andrea Gsur,Peter T. Campbell,Victor Moreno,Pavel Vodicka,Pavel Vodicka,Pavel Vodicka,Ludmila Vodickova,Ludmila Vodickova,Ludmila Vodickova,Hermann Brenner,Jenny Chang-Claude,Jenny Chang-Claude,Michael Hoffmeister,Lori C. Sakoda,Lori C. Sakoda,Martha L. Slattery,Robert E. Schoen,Marc J. Gunter,Sergi Castellví-Bel,Hyeong Rok Kim,Sun-Seog Kweon,Andrew T. Chan,Li Li,Wei Zheng,D. Timothy Bishop,Daniel D. Buchanan,Daniel D. Buchanan,Graham G. Giles,Graham G. Giles,Stephen B. Gruber,Gad Rennert,Zsofia K. Stadler,Tabitha A. Harrison,Yi Lin,Temitope O. Keku,Michael O. Woods,Clemens Schafmayer,Bethany Van Guelpen,Steven Gallinger,Heather Hampel,Sonja I. Berndt,Paul D.P. Pharoah,Annika Lindblom,Annika Lindblom,Alicja Wolk,Alicja Wolk,Anna H. Wu,Emily White,Emily White,Ulrike Peters,Ulrike Peters,David A. Drew,Dominique Scherer,Justo Lorenzo Bermejo,Ann C. Williams,Caroline L Relton +78 more
TL;DR: In this article, the authors combined a proteomic approach with Mendelian randomization (MR) to identify possible new aspirin targets that decrease colorectal cancer (CRC) risk.
Posted ContentDOI
A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer
Aayah Nounu,Aayah Nounu,Alexander Greenhough,Alexander Greenhough,Kate J. Heesom,Rebecca C Richmond,Jie Zheng,Stephanie J. Weinstein,Demetrius Albanes,John A. Baron,John L. Hopper,John L. Hopper,Jane C. Figueiredo,Jane C. Figueiredo,Polly A. Newcomb,Polly A. Newcomb,Noralane M. Lindor,Graham Casey,Elizabeth A. Platz,Loic Le Marchand,Cornelia M. Ulrich,Christopher I. Li,Fränzel J.B. van Duijnhoven,Andrea Gsur,Peter T. Campbell,Victor Moreno,Pavel Vodicka,Pavel Vodicka,Pavel Vodicka,Ludmila Vodickova,Ludmila Vodickova,Ludmila Vodickova,Hermann Brenner,Jenny Chang-Claude,Jenny Chang-Claude,Michael Hoffmeister,Lori C. Sakoda,Lori C. Sakoda,Martha L. Slattery,Robert E. Schoen,Marc J. Gunter,Sergi Castellví-Bel,Hyeong Rok Kim,Sun-Seog Kweon,Andrew T. Chan,Li Li,Wei Zheng,D. Timothy Bishop,Daniel D. Buchanan,Daniel D. Buchanan,Graham G. Giles,Graham G. Giles,Stephen B. Gruber,Gad Rennert,Zsofia K. Stadler,Tabitha A. Harrison,Yi Lin,Temitope O. Keku,Michael O. Woods,Clemens Schafmayer,Bethany Van Guelpen,Steven Gallinger,Heather Hampel,Sonja I. Berndt,Paul D.P. Pharoah,Annika Lindblom,Annika Lindblom,Alicja Wolk,Alicja Wolk,Anna H. Wu,Emily White,Emily White,Ulrike Peters,Ulrike Peters,David A. Drew,Dominique Scherer,Justo Lorenzo Bermejo,Ann C. Williams,Caroline L Relton +78 more
TL;DR: MCM6 and RRM2 are involved in DNA repair whereby reduced expression may lead to increased DNA aberrations and ultimately cancer cell death, whereas ARFIP2 is involved in actin cytoskeletal regulation indicating a possible role in aspirin’s reduction of metastasis.