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Open AccessJournal ArticleDOI

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Theo Vos, +363 more
- 15 Dec 2012 - 
- Vol. 380, Iss: 9859, pp 2163-2196
TLDR
Prevalence and severity of health loss were weakly correlated and age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010, but population growth and ageing have increased YLD numbers and crude rates over the past two decades.
About: 
This article is published in The Lancet.The article was published on 2012-12-15 and is currently open access. It has received 7021 citations till now. The article focuses on the topics: Years of potential life lost & Global health.

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A Persistent Hotspot of Schistosoma mansoni Infection in a Five-Year Randomized Trial of Praziquantel Preventative Chemotherapy Strategies

Ryan E. Wiegand, +11 more
- 12 Dec 2017 - 
TL;DR: During a trial of preventive chemotherapy strategies, a hotspot of Schistosoma mansoni infection was found and villages meeting endpoints at year 5 were predicted from prior data with accuracy.
Journal ArticleDOI

Functional biomarkers for chronic periodontitis and insights into the roles of Prevotella nigrescens and Fusobacterium nucleatum ; a metatranscriptome analysis.

Szymon P. Szafrański, +8 more
TL;DR: Gene biomarkers of periodontitis are highly predictive and discovered the three best functional biomarkers, namely haem binding protein HmuY from Porphyromonas gingivalis, flagellar filament core protein FlaB3 from Treponema denticola, and repeat protein of unknown function from Filifactor alocis.
Journal ArticleDOI

Osteoarthritis Increases the Risk of Dementia: A Nationwide Cohort Study in Taiwan

Shih Wei Huang, +5 more
- 18 May 2015 - 
TL;DR: It is indicated that OA is an independent risk factor for dementia in patients with OA.
Journal ArticleDOI

Basophils trigger emphysema development in a murine model of COPD through IL-4–mediated generation of MMP-12–producing macrophages

Sho Shibata, +7 more
- 18 Dec 2018 - 
TL;DR: The basophil-derived IL-4/monocyte–derived IM/MMP-12 axis plays a crucial role in emphysema formation and therefore may be a potential target to slow down emphySEma progression at the initiation phase of COPD.
Journal ArticleDOI

Exercise therapy for functional capacity in chronic diseases: an overview of meta-analyses of randomised controlled trials

Tero Pasanen, +3 more
- 12 May 2017 - 
TL;DR: All meta-analyses of randomised controlled trials that have evaluated the effects of exercise therapy on functional capacity in patients with chronic diseases appear to be a safe way to improve functional capacity and reduce disability in individuals with chronic disease.
References
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Journal ArticleDOI

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, +195 more
- 15 Dec 2012 - 
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.

The Global Burden of Disease Study

Christopher J L Murray, +1 more
Book

Cancer Incidence in Five Continents

Freddie Bray, +11 more
TL;DR: The aim of this study was to establish a database of histological groups and to provide a level of consistency and quality of data that could be applied in the design of future registries.
Journal ArticleDOI

The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R).

Ronald C. Kessler, +8 more
- 18 Jun 2003 - 
TL;DR: Notably, major depressive disorder is a common disorder, widely distributed in the population, and usually associated with substantial symptom severity and role impairment, and while the recent increase in treatment is encouraging, inadequate treatment is a serious concern.
Book

The global burden of disease: a comprehensive assessment of mortality and disability from diseases injuries and risk factors in 1990 and projected to 2020.

Christopher J L Murray, +1 more
TL;DR: This is the first in a planned series of 10 volumes that will attempt to "summarize epidemiological knowledge about all major conditions and most risk factors" and use historical trends in main determinants to project mortality and disease burden forward to 2020.
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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

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