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Open AccessJournal ArticleDOI

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Theo Vos, +363 more
- 15 Dec 2012 - 
- Vol. 380, Iss: 9859, pp 2163-2196
TLDR
Prevalence and severity of health loss were weakly correlated and age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010, but population growth and ageing have increased YLD numbers and crude rates over the past two decades.
About: 
This article is published in The Lancet.The article was published on 2012-12-15 and is currently open access. It has received 7021 citations till now. The article focuses on the topics: Years of potential life lost & Global health.

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Citations
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Journal ArticleDOI

Review article: depression and the use of antidepressants in patients with chronic liver disease or liver transplantation.

Benjamin H. Mullish, +3 more
- 01 Oct 2014 - 
TL;DR: The scale of depression in patients with chronic liver disease and those who have received orthotopic liver transplantation (OLT) is poorly characterised and Clinicians are uncertain of how best to manage depression within these patients.
Journal ArticleDOI

ISSLS Prize Winner: Vertebral Endplate (Modic) Change is an Independent Risk Factor for Episodes of Severe and Disabling Low Back Pain.

Juhani H. Määttä, +4 more
- 01 Aug 2015 - 
TL;DR: Modic change is an independent risk factor for episodes of severe and disabling LBP in middle-aged women and these observations support further work aimed at identifying the precise histology underlying MC.
Journal ArticleDOI

Post-infectious group A streptococcal autoimmune syndromes and the heart.

William J. Martin, +9 more
- 01 Aug 2015 - 
TL;DR: A model for the pathogenesis of ARF and RHD is discussed in terms of current immunological concepts and the potential for application of in depth "omics" technologies to these ancient scourges.
Journal ArticleDOI

Inadequate pain relief and large functional loss among patients with knee osteoarthritis: evidence from a prospective multinational longitudinal study of osteoarthritis real-world therapies

Philip G. Conaghan, +11 more
- 01 Feb 2015 - 
TL;DR: IPR is common among patients with knee OA requiring analgesics and is associated with large functional loss and impaired QoL, and patients at particular risk of IPR may require greater attention towards their analgesic treatment options.
Journal ArticleDOI

Pain trajectory groups in persons with, or at high risk of, knee osteoarthritis: findings from the Knee Clinical Assessment Study and the Osteoarthritis Initiative.

Elaine Nicholls, +4 more
- 01 Dec 2014 - 
TL;DR: These findings strengthen the grounds for moving beyond a simple stereotype of osteoarthritis as “slowly progressive” and can nevertheless represent a genuinely favourable prognosis for a sizeable minority.
References
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Journal ArticleDOI

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, +195 more
- 15 Dec 2012 - 
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.

The Global Burden of Disease Study

Christopher J L Murray, +1 more
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Cancer Incidence in Five Continents

Freddie Bray, +11 more
TL;DR: The aim of this study was to establish a database of histological groups and to provide a level of consistency and quality of data that could be applied in the design of future registries.
Journal ArticleDOI

The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R).

Ronald C. Kessler, +8 more
- 18 Jun 2003 - 
TL;DR: Notably, major depressive disorder is a common disorder, widely distributed in the population, and usually associated with substantial symptom severity and role impairment, and while the recent increase in treatment is encouraging, inadequate treatment is a serious concern.
Book

The global burden of disease: a comprehensive assessment of mortality and disability from diseases injuries and risk factors in 1990 and projected to 2020.

Christopher J L Murray, +1 more
TL;DR: This is the first in a planned series of 10 volumes that will attempt to "summarize epidemiological knowledge about all major conditions and most risk factors" and use historical trends in main determinants to project mortality and disease burden forward to 2020.
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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

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