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Open AccessJournal ArticleDOI

Global Epidemiology of Campylobacter Infection

TLDR
Overall, campylobacteriosis is still one of the most important infectious diseases that is likely to challenge global health in the years to come.
Abstract
Campylobacter jejuni infection is one of the most widespread infectious diseases of the last century. The incidence and prevalence of campylobacteriosis have increased in both developed and developing countries over the last 10 years. The dramatic increase in North America, Europe, and Australia is alarming, and data from parts of Africa, Asia, and the Middle East indicate that campylobacteriosis is endemic in these areas, especially in children. In addition to C. jejuni, there is increasing recognition of the clinical importance of emerging Campylobacter species, including Campylobacter concisus and Campylobacter ureolyticus. Poultry is a major reservoir and source of transmission of campylobacteriosis to humans. Other risk factors include consumption of animal products and water, contact with animals, and international travel. Strategic implementation of multifaceted biocontrol measures to reduce the transmission of this group of pathogens is paramount for public health. Overall, campylobacteriosis is still one of the most important infectious diseases that is likely to challenge global health in the years to come. This review provides a comprehensive overview of the global epidemiology, transmission, and clinical relevance of Campylobacter infection.

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Citations
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Journal ArticleDOI

Genomic insight into Campylobacter jejuni isolated from commercial turkey flocks in Germany using whole-genome sequencing analysis

TL;DR: In this paper , the authors used whole-genome sequencing (WGS) technology to sequence 66 C. jejuni isolates obtained from commercial turkey farms in Germany using Illumina MiSeq® technology.
Journal ArticleDOI

Study of Prevalence of Campylobacter Gastroenteritis among Pediatric Population Using a Multiplex PCR in a Tertiary Care Hospital in Puducherry, South India

TL;DR: The study reveals that the prevalence of Campylobacter infection was high in Puducherry, and there is an increased need to implement molecular assays for the routine detection of Campyobacter in all clinical pediatric stool samples.
DissertationDOI

Inhibition of the CmeABC efflux pump by antisense peptide nucleic acids reduces the emergence of spontaneous fluoroquinolone resistant mutants in Campylobacter jejuni

Kritika Singh
TL;DR: In vitro and in vivo experiments were conducted to examine the efficacy of the PNA in reducing the emergence of spontaneous fluoroquinolone resistant mutants during treatment with a fluoroquolone antibiotic and the potentiating effect of thePNA on ciprofloxacin.
Journal ArticleDOI

Multiple Campylobacter jejuni proteins affecting the peptidoglycan structure and the degree of helical cell curvature

TL;DR: In this article , the authors used homology searches and bioinformatics to identify additional gene products involved in C. jejuni morphogenesis: the putative bactofilin 1104 and the M23 peptidase domain-containing proteins 0166, 1105, and 1228.
References
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Journal ArticleDOI

Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study.

TL;DR: Interventions targeting five pathogens can substantially reduce the burden of moderate-to-severe diarrhoea and suggest new methods and accelerated implementation of existing interventions (rotavirus vaccine and zinc) are needed to prevent disease and improve outcomes.
Journal ArticleDOI

The functional gastrointestinal disorders and the Rome III process.

TL;DR: Two important processes have occurred to legitimize these conditions, and to increase attention toward the research and clinical care of patients with functional gastrointestinal disorders (FGID), a shift in conceptualizing these disorders from a disease-based, reductionistic model, to a more integrated, biopsychosocial model of illness.
Journal ArticleDOI

Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

TL;DR: Overabundance of Fusobacterium sequences in tumor versus matched normal control tissue is verified by quantitative PCR analysis from a total of 99 subjects, and a positive association with lymph node metastasis is observed.
Journal ArticleDOI

Campylobacter enteritis: a "new" disease.

M B Skirrow
- 02 Jul 1977 - 
TL;DR: Campylobacters are a relatively unrecognised cause of acute enteritis, but these findings suggest that they may be a common cause, and poultry may be the primary source of the organism.
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