Global Epidemiology of Campylobacter Infection
TLDR
Overall, campylobacteriosis is still one of the most important infectious diseases that is likely to challenge global health in the years to come.Abstract:
Campylobacter jejuni infection is one of the most widespread infectious diseases of the last century. The incidence and prevalence of campylobacteriosis have increased in both developed and developing countries over the last 10 years. The dramatic increase in North America, Europe, and Australia is alarming, and data from parts of Africa, Asia, and the Middle East indicate that campylobacteriosis is endemic in these areas, especially in children. In addition to C. jejuni, there is increasing recognition of the clinical importance of emerging Campylobacter species, including Campylobacter concisus and Campylobacter ureolyticus. Poultry is a major reservoir and source of transmission of campylobacteriosis to humans. Other risk factors include consumption of animal products and water, contact with animals, and international travel. Strategic implementation of multifaceted biocontrol measures to reduce the transmission of this group of pathogens is paramount for public health. Overall, campylobacteriosis is still one of the most important infectious diseases that is likely to challenge global health in the years to come. This review provides a comprehensive overview of the global epidemiology, transmission, and clinical relevance of Campylobacter infection.read more
Citations
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Comparative Analysis of L-Fucose Utilization and Its Impact on Growth and Survival of Campylobacter Isolates
Kathleen Born,Ettayb, Jawad +1 more
TL;DR: In this paper , the influence of the L-fucose utilization cluster on Campylobacter growth, survival and metabolism was investigated by comparing genotyping and phenotyping of the C. jejuni reference isolate NCTC11168 (human isolate).
Journal ArticleDOI
In silico prediction and expression analysis of vaccine candidate genes of Campylobacter jejuni.
Sabin Poudel,Linan Jia,Mark A. Arick,Chuan-Yu Hsu,Adam Thrash,A. T. Sukumaran,Pratima Adhikari,Aaron S. Kiess,Li Zhang +8 more
TL;DR: In this article , the authors used the reverse vaccinology approach to identify suitable candidates to develop a subunit vaccine against C. jejuni, which could reduce colonization in the GI tract of the poultry.
Journal ArticleDOI
Should We Consider Them as a Threat? Antimicrobial Resistance, Virulence Potential and Genetic Diversity of Campylobacter spp. Isolated from Varsovian Dogs
Małgorzata Murawska,Monika Sypecka,Justyna Bartosik,Ewelina Kwiecień,Magdalena Rzewuska,Agnieszka Sałamaszyńska-Guz +5 more
TL;DR: The results indicate that dogs may be the reservoir of potentially diverse, potentially virulent, and antimicrobial-resistant Campylobacter strains.
Journal ArticleDOI
Molecular detection and genetic characterization of Arcobacter butzleri isolated from red-footed pet tortoises suspected for Campylobacter spp. from Grenada, West Indies.
Bhumika Sharma,Katelyn Thille,Vanessa Matthew Belmar,Roxanne Nicholas Thomas,Ravindra Sharma +4 more
TL;DR: The aim of the study was to detect and genetically characterize Arcobacter butzleri in pet red-footed tortoises suspected for Campylobacter spp.
Posted ContentDOI
Campylobacter jejuni modulates reactive oxygen species production and NADPH oxidase 1 expression in human intestinal epithelial cells
Geun-Hwa Hong,Cadi Davies,Zahra Omole,Janie Liaw,Anna Grabowska,Barbara Canonico,Nicolae Corcionivoshi,Brendan W. Wren,Nick Dorrell,A Elmi,Ozan Gundogdu +10 more
TL;DR: This work shows that C. jejuni differentially regulates intracellular and extracellular ROS production in human T84 and Caco-2 cells and downregulates the transcription and translation of Nox1, a key ROS-generating enzyme in IECs and antioxidant defence genes cat and sod1.
References
More filters
Journal ArticleDOI
Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study.
Karen L. Kotloff,James P. Nataro,William C. Blackwelder,Dilruba Nasrin,Tamer H. Farag,Sandra Panchalingam,Yukun Wu,Samba O. Sow,Dipika Sur,Robert F. Breiman,Abu Syed Golam Faruque,Anita K. M. Zaidi,Debasish Saha,Pedro L. Alonso,Boubou Tamboura,Doh Sanogo,Uma Onwuchekwa,Byomkesh Manna,Thandavarayan Ramamurthy,Suman Kanungo,John B. Ochieng,Richard Omore,Joseph Oundo,Anowar Hossain,Sumon Kumar Das,Shahnawaz Ahmed,Shahida Qureshi,Farheen Quadri,Richard A. Adegbola,Richard A. Adegbola,Martin Antonio,M. Jahangir Hossain,Adebayo Akinsola,Inacio Mandomando,Tacilta Nhampossa,Sozinho Acácio,Kousick Biswas,Ciara E. O’Reilly,Eric D. Mintz,Lynette Y. Berkeley,Lynette Y. Berkeley,Khitam Muhsen,Halvor Sommerfelt,Halvor Sommerfelt,Roy M. Robins-Browne,Myron M. Levine +45 more
TL;DR: Interventions targeting five pathogens can substantially reduce the burden of moderate-to-severe diarrhoea and suggest new methods and accelerated implementation of existing interventions (rotavirus vaccine and zinc) are needed to prevent disease and improve outcomes.
Journal ArticleDOI
The functional gastrointestinal disorders and the Rome III process.
TL;DR: Two important processes have occurred to legitimize these conditions, and to increase attention toward the research and clinical care of patients with functional gastrointestinal disorders (FGID), a shift in conceptualizing these disorders from a disease-based, reductionistic model, to a more integrated, biopsychosocial model of illness.
Journal ArticleDOI
Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma
Mauro Castellarin,René L. Warren,J. Douglas Freeman,Lisa Dreolini,Martin Krzywinski,Jaclyn Strauss,Rebecca O Barnes,Peter H. Watson,Emma Allen-Vercoe,Richard A. Moore,Robert A. Holt +10 more
TL;DR: Overabundance of Fusobacterium sequences in tumor versus matched normal control tissue is verified by quantitative PCR analysis from a total of 99 subjects, and a positive association with lymph node metastasis is observed.
Journal ArticleDOI
Genomic analysis identifies association of Fusobacterium with colorectal carcinoma
Aleksandar Kostic,Dirk Gevers,Chandra Sekhar Pedamallu,Chandra Sekhar Pedamallu,Monia Michaud,Fujiko Duke,Fujiko Duke,Ashlee M. Earl,Akinyemi I. Ojesina,Akinyemi I. Ojesina,Joonil Jung,Adam J. Bass,Adam J. Bass,Josep Tabernero,José Baselga,Chen Liu,Ramesh A. Shivdasani,Shuji Ogino,Bruce W. Birren,Curtis Huttenhower,Curtis Huttenhower,Wendy S. Garrett,Wendy S. Garrett,Matthew Meyerson,Matthew Meyerson +24 more
TL;DR: The composition of the microbiota in colorectal carcinoma is characterized using whole genome sequences from nine tumor/normal pairs and Fusobacterium sequences were enriched in carcinomas, confirmed by quantitative PCR and 16S rDNA sequence analysis of 95 carcinoma/normal DNA pairs.
Journal ArticleDOI
Campylobacter enteritis: a "new" disease.
TL;DR: Campylobacters are a relatively unrecognised cause of acute enteritis, but these findings suggest that they may be a common cause, and poultry may be the primary source of the organism.
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