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Open AccessJournal ArticleDOI

Global Epidemiology of Campylobacter Infection

TLDR
Overall, campylobacteriosis is still one of the most important infectious diseases that is likely to challenge global health in the years to come.
Abstract
Campylobacter jejuni infection is one of the most widespread infectious diseases of the last century. The incidence and prevalence of campylobacteriosis have increased in both developed and developing countries over the last 10 years. The dramatic increase in North America, Europe, and Australia is alarming, and data from parts of Africa, Asia, and the Middle East indicate that campylobacteriosis is endemic in these areas, especially in children. In addition to C. jejuni, there is increasing recognition of the clinical importance of emerging Campylobacter species, including Campylobacter concisus and Campylobacter ureolyticus. Poultry is a major reservoir and source of transmission of campylobacteriosis to humans. Other risk factors include consumption of animal products and water, contact with animals, and international travel. Strategic implementation of multifaceted biocontrol measures to reduce the transmission of this group of pathogens is paramount for public health. Overall, campylobacteriosis is still one of the most important infectious diseases that is likely to challenge global health in the years to come. This review provides a comprehensive overview of the global epidemiology, transmission, and clinical relevance of Campylobacter infection.

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Journal ArticleDOI

Molecular Targets in Campylobacter Infections

TL;DR: In this article , the authors present a review of the treatment and prevention of Campylobacteriosis in poultry, including anti-pathogenicity and virulence factors involved in motility, adhesion, invasion, oxygen detoxification and biofilm formation.
Journal ArticleDOI

Clinical Manifestations and Risk factors of Campylobacter gastroenteritis in children in Taiwan.

TL;DR: In this article , the potential risk factors, clinical and laboratory manifestations of children with campylobacteriosis under five years old in Taiwan were investigated and a multivariate stepwise logistic regression model was used for identification of risk factors including low parental educational attainment, direct contact with acute gastroenteritis patients, diarrhea in mutually cared children, takeout food and seafood intake.
ComponentDOI

The Structure of the UDP-Glc/GlcNAc 4-Epimerase from the Human Pathogen Campylobacter jejuni

TL;DR: It is shown that ebselen, previously identified for inhibition of HsGalE, is active against CjGNE, suggesting a route for antibiotic development and a mechanistic understanding of how this enzyme catalyzes various interconversions.
Journal ArticleDOI

Identifying the sources of human campylobacteriosis in Nigeria.

TL;DR: A study of the relationships within isolate populations in Nigeria and source attribution analysis of Nigerian human Campylobacter spp. to other animal isolates was carried out to determine the possible sources for human CSA infection in Nigeria as mentioned in this paper .
References
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Journal ArticleDOI

Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study.

TL;DR: Interventions targeting five pathogens can substantially reduce the burden of moderate-to-severe diarrhoea and suggest new methods and accelerated implementation of existing interventions (rotavirus vaccine and zinc) are needed to prevent disease and improve outcomes.
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The functional gastrointestinal disorders and the Rome III process.

TL;DR: Two important processes have occurred to legitimize these conditions, and to increase attention toward the research and clinical care of patients with functional gastrointestinal disorders (FGID), a shift in conceptualizing these disorders from a disease-based, reductionistic model, to a more integrated, biopsychosocial model of illness.
Journal ArticleDOI

Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

TL;DR: Overabundance of Fusobacterium sequences in tumor versus matched normal control tissue is verified by quantitative PCR analysis from a total of 99 subjects, and a positive association with lymph node metastasis is observed.
Journal ArticleDOI

Campylobacter enteritis: a "new" disease.

M B Skirrow
- 02 Jul 1977 - 
TL;DR: Campylobacters are a relatively unrecognised cause of acute enteritis, but these findings suggest that they may be a common cause, and poultry may be the primary source of the organism.
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