Global Epidemiology of Campylobacter Infection
TLDR
Overall, campylobacteriosis is still one of the most important infectious diseases that is likely to challenge global health in the years to come.Abstract:
Campylobacter jejuni infection is one of the most widespread infectious diseases of the last century. The incidence and prevalence of campylobacteriosis have increased in both developed and developing countries over the last 10 years. The dramatic increase in North America, Europe, and Australia is alarming, and data from parts of Africa, Asia, and the Middle East indicate that campylobacteriosis is endemic in these areas, especially in children. In addition to C. jejuni, there is increasing recognition of the clinical importance of emerging Campylobacter species, including Campylobacter concisus and Campylobacter ureolyticus. Poultry is a major reservoir and source of transmission of campylobacteriosis to humans. Other risk factors include consumption of animal products and water, contact with animals, and international travel. Strategic implementation of multifaceted biocontrol measures to reduce the transmission of this group of pathogens is paramount for public health. Overall, campylobacteriosis is still one of the most important infectious diseases that is likely to challenge global health in the years to come. This review provides a comprehensive overview of the global epidemiology, transmission, and clinical relevance of Campylobacter infection.read more
Citations
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Investigating the Campylobacter jejuni Transcriptional Response to Host Intestinal Extracts Reveals the Involvement of a Widely Conserved Iron Uptake System.
Martha M. Liu,Christine J. Boinett,Anson C. K. Chan,Julian Parkhill,Michael E. P. Murphy,Erin C. Gaynor +5 more
TL;DR: Compared the phenotypic and transcriptional responses of C. jejuni to intestinal compositions of humans (disease-susceptible host) and chickens (zoonotic host) by using human fecal and chicken cecal extracts and targeted one specific iron uptake system for further molecular, genetic, and phenotypesic study.
Journal ArticleDOI
Determinants of Campylobacter infection and association with growth and enteric inflammation in children under 2 years of age in low-resource settings
Ahshanul Haque,James A Platts-Mills,Estomih Mduma,Ladaporn Bodhidatta,Pascal O. Bessong,Sadia Shakoor,Gagandeep Kang,Margaret Kosek,Margaret Kosek,Aldo A. M. Lima,Sanjaya K. Shrestha,Ashraful Alam,Alexandre Havt,Amidou Samie,Richard L. Guerrant,Dennis Lang,Mustafa Mahfuz,Zulfiqar A Bhutta,Eric R. Houpt,Tahmeed Ahmed +19 more
TL;DR: The cumulative burden of both Campylobacter jejuni/coli infections and Campyloblacter species were associated with poor growth and increased intestinal inflammation.
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Genetic characterization and epidemiological implications of Campylobacter isolates from wild birds in South Korea
Bai Wei,Min Kang,Hyung-Kwan Jang +2 more
TL;DR: The results of this study show that ST overlap between human and wild bird isolates frequently occurs, and the high prevalence of virulence genes in wildBird isolates indicates that wild birds shed Campylobacter in their faeces that are potentially pathogenic to humans.
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Prevalence and Molecular Characterization of Campylobacter spp. Isolated from Patients with Diarrhea in Shunyi, Beijing.
Ying Li,Shuang Zhang,Mu He,Yanchun Zhang,Yanyan Fu,Hao Liang,Hongbo Jing,Yindong Li,Hongmei Ma,Maojun Zhang +9 more
TL;DR: This is the first study for Campylobacter isolated using the filtration method in China which indicated the Campyloblacter infection might be seriously under-ascertained in the diarrheal patients in China.
Journal ArticleDOI
Vitamin C alleviates acute enterocolitis in Campylobacter jejuni infected mice
Soraya Mousavi,Ulrike Escher,Elisa Thunhorst,Sophie Kittler,Corinna Kehrenberg,Stefan Bereswill,Markus M. Heimesaat +6 more
TL;DR: Due to the potent anti-inflammatory effects observed in the clinical murine C. jejuni-infection model, ascorbate constitutes a promising novel option for prophylaxis and treatment of acute campylobacteriosis.
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