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Open AccessJournal ArticleDOI

Global Epidemiology of Campylobacter Infection

TLDR
Overall, campylobacteriosis is still one of the most important infectious diseases that is likely to challenge global health in the years to come.
Abstract
Campylobacter jejuni infection is one of the most widespread infectious diseases of the last century. The incidence and prevalence of campylobacteriosis have increased in both developed and developing countries over the last 10 years. The dramatic increase in North America, Europe, and Australia is alarming, and data from parts of Africa, Asia, and the Middle East indicate that campylobacteriosis is endemic in these areas, especially in children. In addition to C. jejuni, there is increasing recognition of the clinical importance of emerging Campylobacter species, including Campylobacter concisus and Campylobacter ureolyticus. Poultry is a major reservoir and source of transmission of campylobacteriosis to humans. Other risk factors include consumption of animal products and water, contact with animals, and international travel. Strategic implementation of multifaceted biocontrol measures to reduce the transmission of this group of pathogens is paramount for public health. Overall, campylobacteriosis is still one of the most important infectious diseases that is likely to challenge global health in the years to come. This review provides a comprehensive overview of the global epidemiology, transmission, and clinical relevance of Campylobacter infection.

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Citations
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Journal ArticleDOI

Investigating the Campylobacter jejuni Transcriptional Response to Host Intestinal Extracts Reveals the Involvement of a Widely Conserved Iron Uptake System.

TL;DR: Compared the phenotypic and transcriptional responses of C. jejuni to intestinal compositions of humans (disease-susceptible host) and chickens (zoonotic host) by using human fecal and chicken cecal extracts and targeted one specific iron uptake system for further molecular, genetic, and phenotypesic study.
Journal ArticleDOI

Genetic characterization and epidemiological implications of Campylobacter isolates from wild birds in South Korea

TL;DR: The results of this study show that ST overlap between human and wild bird isolates frequently occurs, and the high prevalence of virulence genes in wildBird isolates indicates that wild birds shed Campylobacter in their faeces that are potentially pathogenic to humans.
Journal ArticleDOI

Prevalence and Molecular Characterization of Campylobacter spp. Isolated from Patients with Diarrhea in Shunyi, Beijing.

TL;DR: This is the first study for Campylobacter isolated using the filtration method in China which indicated the Campyloblacter infection might be seriously under-ascertained in the diarrheal patients in China.
Journal ArticleDOI

Vitamin C alleviates acute enterocolitis in Campylobacter jejuni infected mice

TL;DR: Due to the potent anti-inflammatory effects observed in the clinical murine C. jejuni-infection model, ascorbate constitutes a promising novel option for prophylaxis and treatment of acute campylobacteriosis.
References
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Journal ArticleDOI

Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study.

TL;DR: Interventions targeting five pathogens can substantially reduce the burden of moderate-to-severe diarrhoea and suggest new methods and accelerated implementation of existing interventions (rotavirus vaccine and zinc) are needed to prevent disease and improve outcomes.
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The functional gastrointestinal disorders and the Rome III process.

TL;DR: Two important processes have occurred to legitimize these conditions, and to increase attention toward the research and clinical care of patients with functional gastrointestinal disorders (FGID), a shift in conceptualizing these disorders from a disease-based, reductionistic model, to a more integrated, biopsychosocial model of illness.
Journal ArticleDOI

Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

TL;DR: Overabundance of Fusobacterium sequences in tumor versus matched normal control tissue is verified by quantitative PCR analysis from a total of 99 subjects, and a positive association with lymph node metastasis is observed.
Journal ArticleDOI

Campylobacter enteritis: a "new" disease.

M B Skirrow
- 02 Jul 1977 - 
TL;DR: Campylobacters are a relatively unrecognised cause of acute enteritis, but these findings suggest that they may be a common cause, and poultry may be the primary source of the organism.
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