C
Catharina Lavebratt
Researcher at Karolinska University Hospital
Publications - 188
Citations - 8212
Catharina Lavebratt is an academic researcher from Karolinska University Hospital. The author has contributed to research in topics: Bipolar disorder & Population. The author has an hindex of 40, co-authored 167 publications receiving 6030 citations. Previous affiliations of Catharina Lavebratt include Royal Institute of Technology & Karolinska Institutet.
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Journal ArticleDOI
Genome-wide association study identifies 30 loci associated with bipolar disorder
Eli A. Stahl,Eli A. Stahl,Gerome Breen,Andreas J. Forstner,Andrew McQuillin,Stephan Ripke,Stephan Ripke,Stephan Ripke,Vassily Trubetskoy,Manuel Mattheisen,Yunpeng Wang,Yunpeng Wang,Jonathan R. I. Coleman,Helena Gaspar,Christiaan de Leeuw,Stacy Steinberg,Jennifer M. Whitehead Pavlides,Maciej Trzaskowski,Enda M. Byrne,Tune H. Pers,Tune H. Pers,Peter Holmans,Alexander Richards,Liam Abbott,Esben Agerbo,Esben Agerbo,Huda Akil,Diego Albani,Ney Alliey-Rodriguez,Thomas Damm Als,Thomas Damm Als,Adebayo Anjorin,Verneri Antilla,Swapnil Awasthi,Judith A. Badner,Marie Bækvad-Hansen,Marie Bækvad-Hansen,Jack D. Barchas,Nicholas Bass,Michael Bauer,Richard A. Belliveau,Sarah E. Bergen,Carsten Bøcker Pedersen,Carsten Bøcker Pedersen,Erlend Bøen,Marco P. Boks,James Boocock,Monika Budde,William E. Bunney,Margit Burmeister,Jonas Bybjerg-Grauholm,Jonas Bybjerg-Grauholm,William Byerley,Miquel Casas,Felecia Cerrato,Pablo Cervantes,Kimberly Chambert,Alexander W. Charney,Danfeng Chen,Claire Churchhouse,Claire Churchhouse,Toni-Kim Clarke,William Coryell,David Craig,Cristiana Cruceanu,Cristiana Cruceanu,David Curtis,David Curtis,Piotr M. Czerski,Anders M. Dale,Simone de Jong,Franziska Degenhardt,Jurgen Del-Favero,J. Raymond DePaulo,Srdjan Djurovic,Srdjan Djurovic,Amanda Dobbyn,Ashley Dumont,Torbjørn Elvsåshagen,Valentina Escott-Price,Chun Chieh Fan,Sascha B. Fischer,Sascha B. Fischer,Matthew Flickinger,Tatiana Foroud,Liz Forty,Josef Frank,Christine Fraser,Nelson B. Freimer,Louise Frisén,Katrin Gade,Katrin Gade,Diane Gage,Julie Garnham,Claudia Giambartolomei,Marianne Giørtz Pedersen,Marianne Giørtz Pedersen,Jaqueline Goldstein,Scott D. Gordon,Katherine Gordon-Smith,Elaine K. Green,Melissa J. Green,Melissa J. Green,Tiffany A. Greenwood,Jakob Grove,Weihua Guan,Jose Guzman-Parra,Marian L. Hamshere,Martin Hautzinger,Urs Heilbronner,Stefan Herms,Stefan Herms,Stefan Herms,Maria Hipolito,Per Hoffmann,Per Hoffmann,Per Hoffmann,Dominic Holland,Laura M. Huckins,Stéphane Jamain,Stéphane Jamain,Jessica S. Johnson,Anders Juréus,Radhika Kandaswamy,Robert Karlsson,James L. Kennedy,Sarah Kittel-Schneider,James A. Knowles,Manolis Kogevinas,Anna C. Koller,Ralph W. Kupka,Catharina Lavebratt,Jacob Lawrence,William Lawson,Markus Leber,Phil Lee,Phil Lee,Shawn Levy,Jun Li,Chunyu Liu,Susanne Lucae,Anna Maaser,Donald J. MacIntyre,Pamela B. Mahon,Pamela B. Mahon,Wolfgang Maier,Lina Martinsson,Steve McCarroll,Steve McCarroll,Peter McGuffin,Melvin G. McInnis,James McKay,Helena Medeiros,Sarah E. Medland,Fan Meng,Fan Meng,Lili Milani,Grant W. Montgomery,Derek W. Morris,Derek W. Morris,Thomas W. Mühleisen,Thomas W. Mühleisen,Niamh Mullins,Hoang T. Nguyen,Caroline M. Nievergelt,Caroline M. Nievergelt,Annelie Nordin Adolfsson,Evaristus A. Nwulia,Claire O'Donovan,Loes M. Olde Loohuis,Anil P.S. Ori,Lilijana Oruc,Urban Ösby,Roy H. Perlis,Amy Perry,Andrea Pfennig,James B. Potash,Shaun Purcell,Shaun Purcell,Eline J. Regeer,Andreas Reif,Céline S. Reinbold,Céline S. Reinbold,John P. Rice,Fabio Rivas,Margarita Rivera,Margarita Rivera,Panos Roussos,Douglas M. Ruderfer,Euijung Ryu,Cristina Sánchez-Mora,Cristina Sánchez-Mora,Alan F. Schatzberg,William A. Scheftner,Nicholas J. Schork,Cynthia Shannon Weickert,Cynthia Shannon Weickert,Tatyana Shehktman,Paul D. Shilling,Engilbert Sigurdsson,Claire Slaney,Olav B. Smeland,Olav B. Smeland,Janet L. Sobell,Christine Søholm Hansen,Christine Søholm Hansen,Anne T. Spijker,David St Clair,Michael Steffens,John Strauss,John Strauss,Fabian Streit,Jana Strohmaier,Szabolcs Szelinger,Robert C. Thompson,Thorgeir E. Thorgeirsson,Jens Treutlein,Helmut Vedder,Weiqing Wang,Stanley J. Watson,Thomas W. Weickert,Thomas W. Weickert,Stephanie H. Witt,Simon Xi,Wei Xu,Wei Xu,Allan H. Young,Peter P. Zandi,Peng Zhang,Sebastian Zöllner,Rolf Adolfsson,Ingrid Agartz,Ingrid Agartz,Martin Alda,Martin Alda,Lena Backlund,Bernhard T. Baune,Bernhard T. Baune,Frank Bellivier,Wade H. Berrettini,Joanna M. Biernacka,Douglas Blackwood,Michael Boehnke,Anders D. Børglum,Anders D. Børglum,Aiden Corvin,Nicholas John Craddock,Mark J. Daly,Mark J. Daly,Udo Dannlowski,Tõnu Esko,Bruno Etain,Mark A. Frye,Janice M. Fullerton,Janice M. Fullerton,Elliot S. Gershon,Michael Gill,Fernando S. Goes,Maria Grigoroiu-Serbanescu,Joanna Hauser,David M. Hougaard,David M. Hougaard,Christina M. Hultman,Ian Jones,Lisa Jones,René S. Kahn,George Kirov,Mikael Landén,Mikael Landén,Marion Leboyer,Marion Leboyer,Cathryn M. Lewis,Qingqin S. Li,Jolanta Lissowska,Nicholas G. Martin,Nicholas G. Martin,Fermín Mayoral,Susan L. McElroy,Andrew M. McIntosh,Francis J. McMahon,Ingrid Melle,Andres Metspalu,Philip B. Mitchell,Gunnar Morken,Ole Mors,Ole Mors,Preben Bo Mortensen,Preben Bo Mortensen,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Richard M. Myers,Benjamin M. Neale,Benjamin M. Neale,Vishwajit L. Nimgaonkar,Merete Nordentoft,Merete Nordentoft,Markus M. Nöthen,Michael Conlon O'Donovan,Ketil J. Oedegaard,Michael John Owen,Sara A. Paciga,Carlos N. Pato,Michele T. Pato,Danielle Posthuma,Josep Antoni Ramos-Quiroga,Marta Ribasés,Marta Ribasés,Marcella Rietschel,Guy A. Rouleau,Guy A. Rouleau,Martin Schalling,Peter R. Schofield,Peter R. Schofield,Thomas G. Schulze,Alessandro Serretti,Jordan W. Smoller,Jordan W. Smoller,Hreinn Stefansson,Kari Stefansson,Kari Stefansson,Eystein Stordal,Patrick F. Sullivan,Patrick F. Sullivan,Gustavo Turecki,Arne E. Vaaler,Eduard Vieta,John B. Vincent,Thomas Werge,Thomas Werge,Thomas Werge,John I. Nurnberger,Naomi R. Wray,Arianna Di Florio,Arianna Di Florio,Howard J. Edenberg,Sven Cichon,Roel A. Ophoff,Laura J. Scott,Ole A. Andreassen,Ole A. Andreassen,John R. Kelsoe,Pamela Sklar,Pamela Sklar +342 more
TL;DR: Genome-wide analysis identifies 30 loci associated with bipolar disorder, allowing for comparisons of shared genes and pathways with other psychiatric disorders, including schizophrenia and depression.
Journal ArticleDOI
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Phil Lee,Verneri Anttila,Hyejung Won,Yen-Chen Anne Feng,Jacob Rosenthal,Zhaozhong Zhu,Elliot M. Tucker-Drob,Michel G. Nivard,Andrew D. Grotzinger,Danielle Posthuma,Meg M.-J. Wang,Dongmei Yu,Eli A. Stahl,Raymond K. Walters,Richard Anney,Laramie E. Duncan,Tian Ge,Rolf Adolfsson,Tobias Banaschewski,Sintia Iole Belangero,Edwin H. Cook,Giovanni Coppola,Eske M. Derks,Pieter J. Hoekstra,Jaakko Kaprio,Anna Keski-Rahkonen,George Kirov,George Kirov,Henry R. Kranzler,Jurjen J. Luykx,Luis Augusto Rohde,Clement C. Zai,Esben Agerbo,Maria Arranz,Philip Asherson,Marie Bækvad-Hansen,Gisli Baldursson,Mark A. Bellgrove,Richard A. Belliveau,Jan K. Buitelaar,Christie L. Burton,Jonas Bybjerg-Grauholm,Miquel Casas,Felecia Cerrato,Kimberly Chambert,Claire Churchhouse,Bru Cormand,Jennifer Crosbie,Søren Dalsgaard,Ditte Demontis,Alysa E. Doyle,Ashley Dumont,Josephine Elia,Jakob Grove,Olafur O Gudmundsson,Jan Haavik,Hakon Hakonarson,Christine Søholm Hansen,Catharina A. Hartman,Ziarih Hawi,Amaia Hervás,David M. Hougaard,Daniel P. Howrigan,Hailiang Huang,Jonna Kuntsi,Kate Langley,Klaus-Peter Lesch,Patrick W. L. Leung,Sandra K. Loo,Joanna Martin,Alicia R. Martin,James J. McGough,Sarah E. Medland,Jennifer L. Moran,Ole Mors,Preben Bo Mortensen,Robert D. Oades,Duncan S. Palmer,Carsten Bøcker Pedersen,Marianne Giørtz Pedersen,Triinu Peters,Timothy Poterba,Jesper Buchhave Poulsen,Josep Antoni Ramos-Quiroga,Andreas Reif,Marta Ribasés,Aribert Rothenberger,Paula Rovira,Cristina Sánchez-Mora,F. Kyle Satterstrom,Russell Schachar,María Soler Artigas,Stacy Steinberg,Hreinn Stefansson,Patrick Turley,G. Bragi Walters,Thomas Werge,Tetyana Zayats,Dan E. Arking,Francesco Bettella,Joseph D. Buxbaum,Jane H. Christensen,Ryan L. Collins,Hilary Coon,Silvia De Rubeis,Richard Delorme,Dorothy E. Grice,Thomas Hansen,Peter Holmans,Sigrun Hope,Christina M. Hultman,Lambertus Klei,Christine Ladd-Acosta,Páll Magnússon,Terje Nærland,Mette Nyegaard,Dalila Pinto,Per Qvist,Karola Rehnström,Abraham Reichenberg,Jennifer Reichert,Kathryn Roeder,Guy A. Rouleau,Evald Saemundsen,Stephen Sanders,Sven Sandin,Beate St Pourcain,Kari Stefansson,James S. Sutcliffe,Michael E. Talkowski,Lauren A. Weiss,A. Jeremy Willsey,Ingrid Agartz,Huda Akil,Diego Albani,Martin Alda,Thomas Damm Als,Adebayo Anjorin,Lena Backlund,Nicholas Bass,Michael Bauer,Bernhard T. Baune,Frank Bellivier,Sarah E. Bergen,Wade H. Berrettini,Joanna M. Biernacka,Douglas Blackwood,Erlend Bøen,Monika Budde,William E. Bunney,Margit Burmeister,William Byerley,Enda M. Byrne,Sven Cichon,Toni-Kim Clarke,Jonathan R. I. Coleman,Nicholas John Craddock,David Curtis,Piotr M. Czerski,Anders M. Dale,Nina Dalkner,Udo Dannlowski,Franziska Degenhardt,Arianna Di Florio,Torbjørn Elvsåshagen,Bruno Etain,Sascha B. Fischer,Andreas J. Forstner,Liz Forty,Josef Frank,Mark A. Frye,Janice M. Fullerton,Katrin Gade,Helena Gaspar,Elliot S. Gershon,Michael Gill,Fernando S. Goes,Scott D. Gordon,Katherine Gordon-Smith,Melissa J. Green,Tiffany A. Greenwood,Maria Grigoroiu-Serbanescu,Jose Guzman-Parra,Joanna Hauser,Martin Hautzinger,Urs Heilbronner,Stefan Herms,Per Hoffmann,Dominic Holland,Stéphane Jamain,Ian Jones,Lisa Jones,Radhika Kandaswamy,John R. Kelsoe,James L. Kennedy,Oedegaard Ketil Joachim,Sarah Kittel-Schneider,Manolis Kogevinas,Anna C. Koller,Catharina Lavebratt,Cathryn M. Lewis,Qingqin S. Li,Jolanta Lissowska,Loes M. Olde Loohuis,Susanne Lucae,Anna Maaser,Ulrik Fredrik Malt,Nicholas G. Martin,Lina Martinsson,Susan L. McElroy,Francis J. McMahon,Andrew McQuillin,Ingrid Melle,Andres Metspalu,Vincent Millischer,Philip B. Mitchell,Grant W. Montgomery,Gunnar Morken,Derek W. Morris,Bertram Müller-Myhsok,Niamh Mullins,Richard M. Myers,Caroline M. Nievergelt,Merete Nordentoft,Annelie Nordin Adolfsson,Markus M. Nöthen,Roel A. Ophoff,Michael John Owen,Sara A. Paciga,Carlos N. Pato,Michele T. Pato,Roy H. Perlis,Amy Perry,James B. Potash,Céline S. Reinbold,Marcella Rietschel,Margarita Rivera,Mary Roberson,Martin Schalling,Peter R. Schofield,Thomas G. Schulze,Laura J. Scott,Alessandro Serretti,Engilbert Sigurdsson,Olav B. Smeland,Eystein Stordal,Fabian Streit,Jana Strohmaier,Thorgeir E. Thorgeirsson,Jens Treutlein,Gustavo Turecki,Arne E. Vaaler,Eduard Vieta,John B. Vincent,Yunpeng Wang,Stephanie H. Witt,Peter P. Zandi,Roger A.H. Adan,Lars Alfredsson,Tetsuya Ando,Harald N. Aschauer,Jessica H. Baker,Vladimir Bencko,Andrew W. Bergen,Andreas Birgegård,Vesna Boraska Perica,Harry Brandt,Roland Burghardt,Laura Carlberg,Matteo Cassina,Maurizio Clementi,Philippe Courtet,Steven Crawford,Scott J. Crow,James J. Crowley,Unna N. Danner,Oliver S. P. Davis,Daniela Degortes,Janiece E. DeSocio,Danielle M. Dick,Christian Dina,Elisa Docampo,Karin Egberts,Stefan Ehrlich,Thomas Espeseth,Fernando Fernández-Aranda,Manfred M. Fichter,Lenka Foretova,Monica Forzan,Giovanni Gambaro,Ina Giegling,Fragiskos Gonidakis,Philip Gorwood,Monica Gratacos Mayora,Yiran Guo,Katherine A. Halmi,Konstantinos Hatzikotoulas,Johannes Hebebrand,Sietske G. Helder,Beate Herpertz-Dahlmann,Wolfgang Herzog,Anke Hinney,Hartmut Imgart,Susana Jiménez-Murcia,Craig Johnson,Jennifer Jordan,Antonio Julià,Deborah Kaminská,Leila Karhunen,Andreas Karwautz,Martien J H Kas,Walter H. Kaye,Martin A. Kennedy,Youl-Ri Kim,Lars Klareskog,Kelly L. Klump,Gun Peggy Knudsen,Mikael Landén,Stephanie Le Hellard,Robert D. Levitan,Dong Li,Paul Lichtenstein,Mario Maj,Sara Marsal,Sara McDevitt,James R. Mitchell,Palmiero Monteleone,Alessio Maria Monteleone,Melissa A. Munn-Chernoff,Benedetta Nacmias,Marie Navratilova,Julie K. O'Toole,Leonid Padyukov,Jacques Pantel,Hana Papezova,Raquel Rabionet,Anu Raevuori,Nicolas Ramoz,Ted Reichborn-Kjennerud,Valdo Ricca,Marion Roberts,Dan Rujescu,Filip Rybakowski,André Scherag,Ulrike Schmidt,Jochen Seitz,Lenka Slachtova,Margarita C T Slof-Op 't Landt,Agnieszka Słopień,Sandro Sorbi,Lorraine Southam,Michael Strober,Alfonso Tortorella,Federica Tozzi,Janet Treasure,Konstantinos Tziouvas,Annemarie A. van Elburg,Tracey D. Wade,Gudrun Wagner,Esther Walton,Hunna J. Watson,H-Erich Wichmann,D. Blake Woodside,Eleftheria Zeggini,Stephanie Zerwas,Stephan Zipfel,Mark Adams,Till F. M. Andlauer,Klaus Berger,Elisabeth B. Binder,Dorret I. Boomsma,Enrique Castelao,Lucía Colodro-Conde,Nese Direk,Anna R. Docherty,Enrico Domenici,Katharina Domschke,Erin C. Dunn,Jerome C. Foo,E.J.C. de Geus,Hans J. Grabe,Steven P. Hamilton,Carsten Horn,Jouke-Jan Hottenga,David M. Howard,Marcus Ising,Stefan Kloiber,Douglas F. Levinson,Glyn Lewis,Patrik K. E. Magnusson,Hamdi Mbarek,Christel M. Middeldorp,Sara Mostafavi,Dale R. Nyholt,Brenda W.J.H. Penninx,Roseann E. Peterson,Giorgio Pistis,David J. Porteous,Martin Preisig,Jorge A. Quiroz,Catherine Schaefer,Eva C. Schulte,Jianxin Shi,Daniel J. Smith,Pippa A. Thomson,Henning Tiemeier,Rudolf Uher,Sandra Van der Auwera,Myrna M. Weissman,Madeline Alexander,Martin Begemann,Elvira Bramon,Nancy G. Buccola,Murray J. Cairns,Dominique Campion,Vaughan J. Carr,C. Robert Cloninger,David Cohen,David A. Collier,Aiden Corvin,Lynn E. DeLisi,Gary Donohoe,Frank Dudbridge,Jubao Duan,Robert B. Freedman,Pablo V. Gejman,Vera Golimbet,Stephanie Godard,Hannelore Ehrenreich,Annette M. Hartmann,Frans Henskens,Masashi Ikeda,Nakao Iwata,Assen Jablensky,Inge Joa,Erik G. Jönsson,Brian Kelly,Jo Knight,Bettina Konte,Claudine Laurent-Levinson,James Lee,Todd Lencz,Bernard Lerer,Carmel M. Loughland,Anil K. Malhotra,Jacques Mallet,Colm McDonald,Marina Mitjans,Bryan J. Mowry,Kieran C. Murphy,Robin M. Murray,F. Anthony O'Neill,Sang-Yun Oh,Aarno Palotie,Christos Pantelis,Ann E. Pulver,Tracey L. Petryshen,Digby Quested,Brien P. Riley,Alan R. Sanders,Ulrich Schall,Sibylle G. Schwab,Rodney J. Scott,Pak C. Sham,Jeremy M. Silverman,Kang Sim,Agnes A. Steixner,Paul A. Tooney,Jim van Os,Marquis P. Vawter,Dermot Walsh,Mark Weiser,Dieter B. Wildenauer,Nigel Williams,Brandon Wormley,Fuquan Zhang,Christos Androutsos,Paul D. Arnold,Cathy L. Barr,Csaba Barta,Katharina Bey,O. Joseph Bienvenu,Donald W. Black,Lawrence W. Brown,Cathy L. Budman,Danielle C. Cath,Keun-Ah Cheon,Valentina Ciullo,Barbara J. Coffey,Daniele Cusi,Lea K. Davis,Damiaan Denys,Christel Depienne,Andrea Dietrich,Valsamma Eapen,Peter Falkai,Thomas V. Fernandez,Blanca Garcia-Delgar,Daniel A. Geller,Donald L. Gilbert,Marco A. Grados,Erica Greenberg,Edna Grünblatt,Julie Hagstrøm,Gregory L. Hanna,Andreas Hartmann,Tammy Hedderly,Gary A. Heiman,Isobel Heyman,Hyun Ju Hong,Alden Y. Huang,Chaim Huyser,Laura Ibanez-Gomez,Ekaterina A. Khramtsova,Young Key Kim,Young Shin Kim,Robert A. King,Yun-Joo Koh,Anastasios Konstantinidis,Sodahm Kook,Samuel Kuperman,Bennett L. Leventhal,Christine Lochner,Andrea G. Ludolph,Marcos Madruga-Garrido,Irene A. Malaty,Athanasios Maras,James T. McCracken,Inge A. Meijer,Pablo Mir,Astrid Morer,Kirsten R. Müller-Vahl,Alexander Münchau,Tara Murphy,Allan L. Naarden,Peter Nagy,Gerald Nestadt,Paul S. Nestadt,Humberto Nicolini,Erika L. Nurmi,Michael S. Okun,Peristera Paschou,Fabrizio Piras,Federica Piras,Christopher Pittenger,Kerstin J. Plessen,Margaret A. Richter,Renata Rizzo,Mary M. Robertson,Veit Roessner,Stephan Ruhrmann,Jack Samuels,Paul Sandor,Monika Schlögelhofer,Eun-Young Shin,Harvey S. Singer,Dong-Ho Song,Jungeun Song,Gianfranco Spalletta,Dan J. Stein,S. Evelyn Stewart,Eric A. Storch,Barbara E. Stranger,Manfred Stuhrmann,Zsanett Tarnok,Jay A. Tischfield,Jennifer Tübing,Frank Visscher,Nienke Vulink,Michael Wagner,Susanne Walitza,Sina Wanderer,Martin Woods,Yulia Worbe,Gwyneth Zai,Samuel H. Zinner,Patrick F. Sullivan,Barbara Franke,Mark J. Daly,Cynthia M. Bulik,Andrew M. McIntosh,Michael Conlon O'Donovan,Amanda B Zheutlin,Ole A. Andreassen,Anders D. Børglum,Gerome Breen,Howard J. Edenberg,Ayman H. Fanous,Stephen V. Faraone,Joel Gelernter,Carol A. Mathews,Manuel Mattheisen,Karen S. Mitchell,Michael C. Neale,John I. Nurnberger,Stephan Ripke,Susan L. Santangelo,Jeremiah M. Scharf,Murray B. Stein,Laura M. Thornton,James T.R. Walters,Naomi R. Wray,Naomi R. Wray,Daniel H. Geschwind,Benjamin M. Neale,Kenneth S. Kendler,Jordan W. Smoller +606 more
TL;DR: Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci within genes that show heightened expression in the brain throughout the lifespan, beginning prenatally in the second trimester, and play prominent roles in neurodevelopmental processes.
Journal ArticleDOI
Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report
Mirko Manchia,Mazda Adli,Nirmala Akula,Raffaella Ardau,Jean-Michel Aubry,Lena Backlund,Claudio E. M. Banzato,Bernhard T. Baune,Frank Bellivier,Susanne Bengesser,Joanna M. Biernacka,Clara Brichant-Petitjean,Elise Bui,Cynthia V. Calkin,Andrew T. A. Cheng,Caterina Chillotti,Sven Cichon,Scott R. Clark,Piotr M. Czerski,Clarissa de Rosalmeida Dantas,Maria Del Zompo,J. Raymond DePaulo,Sevilla D. Detera-Wadleigh,Bruno Etain,Peter Falkai,Louise Frisén,Mark A. Frye,Janice M. Fullerton,Sébastien Gard,Julie Garnham,Fernando S. Goes,Paul Grof,Oliver Gruber,Ryota Hashimoto,Joanna Hauser,Urs Heilbronner,Rebecca Hoban,Rebecca Hoban,Liping Hou,Stéphane Jamain,Jean-Pierre Kahn,Layla Kassem,Tadafumi Kato,John R. Kelsoe,John R. Kelsoe,Sarah Kittel-Schneider,Sebastian Kliwicki,Po-Hsiu Kuo,Ichiro Kusumi,Gonzalo Laje,Catharina Lavebratt,Marion Leboyer,Susan G. Leckband,Susan G. Leckband,Carlos Jaramillo,Mario Maj,Alain Malafosse,Lina Martinsson,Takuya Masui,Philip B. Mitchell,Frank Mondimore,Palmiero Monteleone,Audrey Nallet,Maria Neuner,Tomas Novak,Claire O'Donovan,Urban Ösby,Norio Ozaki,Norio Ozaki,Roy H. Perlis,Andrea Pfennig,James B. Potash,James B. Potash,Daniela Reich-Erkelenz,Andreas Reif,Eva Z. Reininghaus,Sara Richardson,Guy A. Rouleau,Janusz K. Rybakowski,Martin Schalling,Peter R. Schofield,O. Schubert,Barbara W. Schweizer,Florian Seemüller,Maria Grigoroiu-Serbanescu,Giovanni Severino,Lisa R. Seymour,Claire Slaney,Jordan W. Smoller,Alessio Squassina,Thomas Stamm,Jo Steele,Pavla Stopkova,Sarah K. Tighe,Alfonso Tortorella,Gustavo Turecki,Naomi R. Wray,Adam Wright,Peter P. Zandi,David Zilles,Michael Bauer,Marcella Rietschel,Francis J. McMahon,Thomas G. Schulze,Martin Alda +104 more
TL;DR: The key phenotypic measures of the “Retrospective Criteria of Long-Term Treatment Response in Research Subjects with Bipolar Disorder” scale currently used in the Consortium on lithium Genetics (ConLiGen) study are reported.
Journal ArticleDOI
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Niamh Mullins,Andreas J. Forstner,Andreas J. Forstner,Andreas J. Forstner,Kevin S. O’Connell,Kevin S. O’Connell,Brandon J. Coombes,Jonathan R. I. Coleman,Zhen Qiao,Thomas Damm Als,Thomas Damm Als,Tim B. Bigdeli,Tim B. Bigdeli,Sigrid Børte,Sigrid Børte,Sigrid Børte,Julien Bryois,Alexander W. Charney,Ole Kristian Drange,Michael J. Gandal,Saskia P. Hagenaars,Masashi Ikeda,Nolan Kamitaki,Nolan Kamitaki,Minsoo Kim,Kristi Krebs,Georgia Panagiotaropoulou,Brian M. Schilder,Laura G. Sloofman,Stacy Steinberg,Vassily Trubetskoy,Bendik S. Winsvold,Bendik S. Winsvold,Hong-Hee Won,Liliya Abramova,Kristina Adorjan,Esben Agerbo,Esben Agerbo,Mariam M. Al Eissa,Diego Albani,Ney Alliey-Rodriguez,Ney Alliey-Rodriguez,Adebayo Anjorin,Verneri Antilla,Anastasia Antoniou,Swapnil Awasthi,Ji Hyun Baek,Marie Bækvad-Hansen,Marie Bækvad-Hansen,Nicholas Bass,Michael Bauer,Eva C. Beins,Sarah E. Bergen,Armin Birner,Carsten Bøcker Pedersen,Carsten Bøcker Pedersen,Erlend Bøen,Marco P. Boks,Rosa Bosch,Murielle Brum,Ben Michael Brumpton,Nathalie Brunkhorst-Kanaan,Monika Budde,Jonas Bybjerg-Grauholm,Jonas Bybjerg-Grauholm,William Byerley,Murray J. Cairns,Miquel Casas,Pablo Cervantes,Toni-Kim Clarke,Cristiana Cruceanu,Cristiana Cruceanu,Alfredo B. Cuellar-Barboza,Alfredo B. Cuellar-Barboza,Julie M. Cunningham,David Curtis,David Curtis,Piotr M. Czerski,Anders M. Dale,Nina Dalkner,Friederike Sophie David,Franziska Degenhardt,Franziska Degenhardt,Srdjan Djurovic,Srdjan Djurovic,Amanda Dobbyn,Athanassios Douzenis,Torbjørn Elvsåshagen,Torbjørn Elvsåshagen,Valentina Escott-Price,I. Nicol Ferrier,Alessia Fiorentino,Tatiana Foroud,Liz Forty,Josef Frank,Oleksandr Frei,Oleksandr Frei,Nelson B. Freimer,Nelson B. Freimer,Louise Frisén,Katrin Gade,Katrin Gade,Julie Garnham,Joel Gelernter,Joel Gelernter,Marianne Giørtz Pedersen,Marianne Giørtz Pedersen,Ian R. Gizer,Scott D. Gordon,Katherine Gordon-Smith,Tiffany A. Greenwood,Jakob Grove,Jose Guzman-Parra,Kyooseob Ha,Magnús Haraldsson,Martin Hautzinger,Urs Heilbronner,Dennis Hellgren,Stefan Herms,Stefan Herms,Stefan Herms,Per Hoffmann,Per Hoffmann,Per Hoffmann,Peter Holmans,Laura M. Huckins,Stéphane Jamain,Stéphane Jamain,Jessica S. Johnson,Janos Kalman,Yoichiro Kamatani,James L. Kennedy,Sarah Kittel-Schneider,James A. Knowles,Manolis Kogevinas,Maria Koromina,Thorsten M. Kranz,Henry R. Kranzler,Michiaki Kubo,Ralph W. Kupka,Steven A. Kushner,Catharina Lavebratt,Catharina Lavebratt,Jacob Lawrence,Markus Leber,Heon Jeong Lee,Phil Lee,Shawn Levy,Catrin Lewis,Calwing Liao,Calwing Liao,Susanne Lucae,Martin Lundberg,Martin Lundberg,Donald J. MacIntyre,Sigurdur H. Magnusson,Wolfgang Maier,Adam X. Maihofer,Dolores Malaspina,Eirini Maratou,Lina Martinsson,Manuel Mattheisen,Steven A. McCarroll,Steven A. McCarroll,Nathaniel W. McGregor,Peter McGuffin,James McKay,Helena Medeiros,Sarah E. Medland,Vincent Millischer,Vincent Millischer,Grant W. Montgomery,Jennifer L. Moran,Jennifer L. Moran,Derek W. Morris,Thomas W. Mühleisen,Thomas W. Mühleisen,Niamh L. O'Brien,Claire O'Donovan,Loes M. Olde Loohuis,Loes M. Olde Loohuis,Lilijana Oruc,Sergi Papiol,Antonio F. Pardiñas,Amy Perry,Andrea Pfennig,Evgenia Porichi,James B. Potash,Digby Quested,Digby Quested,Towfique Raj,Mark Hyman Rapaport,J. Raymond DePaulo,Eline J. Regeer,John P. Rice,Fabio Rivas,Margarita Rivera,Julian Roth,Panos Roussos,Douglas M. Ruderfer,Cristina Sánchez-Mora,Eva C. Schulte,Fanny Senner,Sally I. Sharp,Paul D. Shilling,Engilbert Sigurdsson,Lea Sirignano,Claire Slaney,Olav B. Smeland,Olav B. Smeland,Daniel J. Smith,Janet L. Sobell,Christine Søholm Hansen,Christine Søholm Hansen,María Soler Artigas,Anne T. Spijker,Dan J. Stein,John Strauss,Beata Świątkowska,Chikashi Terao,Thorgeir E. Thorgeirsson,Claudio Toma,Claudio Toma,Claudio Toma,Paul A. Tooney,Evangelia-Eirini Tsermpini,Marquis P. Vawter,Helmut Vedder,James T.R. Walters,Stephanie H. Witt,Simon Xi,Wei Xu,Jessica Yang,Allan H. Young,Allan H. Young,Hannah Young,Peter P. Zandi,Hang Zhou,Hang Zhou,Lea Zillich,Rolf Adolfsson,Ingrid Agartz,Ingrid Agartz,Martin Alda,Martin Alda,Lars Alfredsson,Gulja Babadjanova,Lena Backlund,Lena Backlund,Bernhard T. Baune,Bernhard T. Baune,Bernhard T. Baune,Frank Bellivier,Susanne Bengesser,Wade H. Berrettini,Douglas Blackwood,Michael Boehnke,Anders D. Børglum,Anders D. Børglum,Gerome Breen,Vaughan J. Carr,Stanley V. Catts,Aiden Corvin,Nicholas John Craddock,Udo Dannlowski,Dimitris Dikeos,Tõnu Esko,Bruno Etain,Panagiotis Ferentinos,Panagiotis Ferentinos,Mark A. Frye,Janice M. Fullerton,Janice M. Fullerton,Micha Gawlik,Elliot S. Gershon,Fernando S. Goes,Melissa J. Green,Melissa J. Green,Maria Grigoroiu-Serbanescu,Joanna Hauser,Frans Henskens,Jan Hillert,Kyung Sue Hong,David M. Hougaard,David M. Hougaard,Christina M. Hultman,Kristian Hveem,Nakao Iwata,Assen Jablensky,Ian Jones,Lisa Jones,René S. Kahn,John R. Kelsoe,George Kirov,Mikael Landén,Mikael Landén,Marion Leboyer,Marion Leboyer,Cathryn M. Lewis,Qingqin S. Li,Jolanta Lissowska,Christine Lochner,Carmel M. Loughland,Nicholas G. Martin,Nicholas G. Martin,Carol A. Mathews,Fermín Mayoral,Susan L. McElroy,Andrew M. McIntosh,Francis J. McMahon,Ingrid Melle,Ingrid Melle,Patricia T. Michie,Lili Milani,Philip B. Mitchell,Gunnar Morken,Ole Mors,Ole Mors,Preben Bo Mortensen,Bryan J. Mowry,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Richard M. Myers,Benjamin M. Neale,Benjamin M. Neale,Caroline M. Nievergelt,Caroline M. Nievergelt,Merete Nordentoft,Merete Nordentoft,Markus M. Nöthen,Michael Conlon O'Donovan,Ketil J. Oedegaard,Tomas Olsson,Michael John Owen,Sara A. Paciga,C Pantelis,Carlos N. Pato,Michele T. Pato,George P. Patrinos,George P. Patrinos,Roy H. Perlis,Danielle Posthuma,Josep Antoni Ramos-Quiroga,Andreas Reif,Eva Z. Reininghaus,Marta Ribasés,Marcella Rietschel,Stephan Ripke,Stephan Ripke,Stephan Ripke,Guy A. Rouleau,Guy A. Rouleau,Takeo Saito,Ulrich Schall,Martin Schalling,Martin Schalling,Peter R. Schofield,Peter R. Schofield,Thomas G. Schulze,Laura J. Scott,Rodney J. Scott,Alessandro Serretti,Cynthia Shannon Weickert,Cynthia Shannon Weickert,Cynthia Shannon Weickert,Jordan W. Smoller,Jordan W. Smoller,Hreinn Stefansson,Kari Stefansson,Kari Stefansson,Eystein Stordal,Fabian Streit,Patrick F. Sullivan,Patrick F. Sullivan,Gustavo Turecki,Arne E. Vaaler,Eduard Vieta,John B. Vincent,Irwin D. Waldman,Thomas W. Weickert,Thomas W. Weickert,Thomas W. Weickert,Thomas Werge,Naomi R. Wray,John-Anker Zwart,John-Anker Zwart,John-Anker Zwart,Joanna M. Biernacka,John I. Nurnberger,Sven Cichon,Howard J. Edenberg,Howard J. Edenberg,Eli A. Stahl,Eli A. Stahl,Andrew McQuillin,Arianna Di Florio,Arianna Di Florio,Roel A. Ophoff,Ole A. Andreassen,Ole A. Andreassen +399 more
TL;DR: The authors performed a genome-wide association study of 41,917 bipolar disorder cases and 371,549 controls of European ancestry, which identified 64 associated genomic loci, including genes encoding targets of antipsychotics, calcium channel blockers, antiepileptics and anesthetics.
Journal ArticleDOI
Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study
Liping Hou,Urs Heilbronner,Urs Heilbronner,Franziska Degenhardt,Mazda Adli,Kazufumi Akiyama,Nirmala Akula,Raffaella Ardau,Bárbara Arias,Lena Backlund,Claudio E. M. Banzato,Antoni Benabarre,Susanne Bengesser,Abesh Kumar Bhattacharjee,Joanna M. Biernacka,Armin Birner,Clara Brichant-Petitjean,Elise T. Bui,Pablo Cervantes,Guo-Bo Chen,Hsi-Chung Chen,Caterina Chillotti,Sven Cichon,Sven Cichon,Scott R. Clark,Francesc Colom,David A. Cousins,Cristiana Cruceanu,Piotr M. Czerski,Clarissa de Rosalmeida Dantas,Alexandre Dayer,Bruno Etain,Peter Falkai,Andreas J. Forstner,Louise Frisén,Janice M. Fullerton,Janice M. Fullerton,Sébastien Gard,Julie Garnham,Fernando S. Goes,Paul Grof,Oliver Gruber,Ryota Hashimoto,Joanna Hauser,Stefan Herms,Stefan Herms,Per Hoffmann,Per Hoffmann,Andrea Hofmann,Stéphane Jamain,Esther Jiménez,Jean-Pierre Kahn,Layla Kassem,Sarah Kittel-Schneider,Sebastian Kliwicki,Barbara König,Ichiro Kusumi,N. Lackner,Gonzalo Laje,Mikael Landén,Mikael Landén,Catharina Lavebratt,Marion Leboyer,Susan G. Leckband,Susan G. Leckband,Carlos Jaramillo,Glenda MacQueen,Mirko Manchia,Mirko Manchia,Lina Martinsson,Manuel Mattheisen,Michael McCarthy,Susan L. McElroy,Marina Mitjans,Francis M. Mondimore,Palmiero Monteleone,Palmiero Monteleone,Caroline M. Nievergelt,Markus M. Nöthen,Urban Ösby,Norio Ozaki,Roy H. Perlis,Andrea Pfennig,Daniela Reich-Erkelenz,Guy A. Rouleau,Peter R. Schofield,Peter R. Schofield,K Oliver Schubert,Barbara W. Schweizer,Florian Seemüller,Giovanni Severino,Tatyana Shekhtman,Tatyana Shekhtman,Paul D. Shilling,Kazutaka Shimoda,Christian Simhandl,Claire Slaney,Jordan W. Smoller,Alessio Squassina,Thomas Stamm,Pavla Stopkova,Sarah K. Tighe,Sarah K. Tighe,Alfonso Tortorella,Gustavo Turecki,Julia Volkert,Stephanie H. Witt,Adam Wright,L. Trevor Young,Peter P. Zandi,James B. Potash,J. Raymond DePaulo,Michael Bauer,Eva Z. Reininghaus,Tomas Novak,Jean-Michel Aubry,Mario Maj,Bernhard T. Baune,Philip B. Mitchell,Eduard Vieta,Mark A. Frye,Janusz K. Rybakowski,Po-Hsiu Kuo,Tadafumi Kato,Maria Grigoroiu-Serbanescu,Andreas Reif,Maria Del Zompo,Frank Bellivier,Martin Schalling,Naomi R. Wray,John R. Kelsoe,John R. Kelsoe,Martin Alda,Martin Alda,Marcella Rietschel,Francis J. McMahon,Thomas G. Schulze +136 more
TL;DR: A genome-wide association study of lithium response in 2,563 patients collected by 22 participating sites from the International Consortium on Lithium Genetics (ConLiGen); the largest attempted so far finds a single locus of four linked SNPs on chromosome 21 met genome- wide significance criteria for association with lithium response.