Anthony C. H. Ng

TL;DR: The flagship paper of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium describes the generation of the integrative analyses of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types, the structures for international data sharing and standardized analyses, and the main scientific findings from across the consortium studies.

TL;DR: Two signatures of somatic mutation characterize ionizing radiation exposure irrespective of tumour type, and a significant increase in balanced inversions in radiation-associated tumours is observed.

TL;DR: Joint analysis of new and previously published sequencing data for primary and metastatic prostate cancers identifies new candidate driver mutations and provides insights into disease progression and potential drug targets.

TL;DR: It has been found that the cerium center adopts an intermediate valence in these complexes, which assumes a virtually trivalent state in cerium bis(tetra-tert-butylnaphthalocyaninato) as a result of the two electron rich naphthalOCyaninatos ligands, which facilitate the delocalization of electron from the ligands to the metal center.

TL;DR: A series of phthalocyanines containing four dendritic substituents with terminal ester or carboxylate functionalities have been synthesized in this paper, and the rates of quenching depend largely on the size of the dendrons.