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Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Theo Vos, +2419 more
- 17 Oct 2020 - 
- Vol. 396, Iss: 10258, pp 1204-1222
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TLDR
Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates, and there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries.
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This article is published in The Lancet.The article was published on 2020-10-17 and is currently open access. It has received 5802 citations till now. The article focuses on the topics: Disease burden & Years of potential life lost.

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Sedentary behaviour is associated with heightened cardiovascular, inflammatory and cortisol reactivity to acute psychological stress

TL;DR: In this article , the authors examined associations between device-assessed sedentary behaviour and measures of stress reactivity and found that higher volumes of daily sedentary behavior were associated with larger stress responses for diastolic blood pressure (Β=1.264, 95%CI=0.109-0.139-2.549, p < .001).
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Circ_0004354 might compete with circ_0040039 to induce NPCs death and inflammatory response by targeting miR-345-3p-FAF1/TP73 axis in intervertebral disc degeneration

TL;DR: A novel insight is offered into the circRNAs-mediated posttranscriptional regulatory network in IVDD, contributing to further clarification of the pathological mechanism of IVDD to develop a promising therapeutic target for IVDD diseases.
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Effectiveness of community-based cardiovascular disease prevention interventions to improve physical activity: A systematic review and meta-regression

TL;DR: In this article, a systematic review and meta-analysis of community-based preventive interventions aimed at improving physical activity (PA) level was performed, which showed that interventions targeting high-risk groups showed greater effectiveness than those targeting the general population (OR: 1.30-2.39 vs 1.12-1.91).
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BDNF blood levels after electroconvulsive therapy in patients with mood disorders: An updated systematic review and meta-analysis

TL;DR: A systematic review and meta-analysis to explore BDNF changes after electroconvulsive therapy (ECT) for the treatment of depression was presented in this article . But, there was evidence of substantial heterogeneity and there were limited sample sizes.
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Inclusion of participants from low-income and middle-income countries in core outcome sets development: a systematic review.

TL;DR: In this paper, the authors describe differences or similarities in the scope, participant characteristics and methods used in core outcome sets (COS) development when only participants from high-income countries (HICs) were involved compared with when participants from low-income and middle-world countries (LMIC) were also involved.
References
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Journal ArticleDOI

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Theo Vos, +778 more
- 16 Sep 2017 - 
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195 countries and territories from 1990 to 2016.
Journal ArticleDOI

Global, regional, and national incidence, prevalence, andyears lived with disability for 354 diseases and injuries for195 countries and territories, 1990–2017: a systematicanalysis for the Global Burden of Disease Study 2017

TL;DR: All-cause age-standardised YLD rates decreased by 3·9% from 1990 to 2017; however, the all-age YLD rate increased by 7·2% while the total sum of global YLDs increased from 562 million (421–723) to 853 million (642–1100).
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Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017

Gregory A. Roth, +1028 more
- 10 Nov 2018 - 
TL;DR: Non-communicable diseases comprised the greatest fraction of deaths, contributing to 73·4% (95% uncertainty interval [UI] 72·5–74·1) of total deaths in 2017, while communicable, maternal, neonatal, and nutritional causes accounted for 18·6% (17·9–19·6), and injuries 8·0% (7·7–8·2).
Journal ArticleDOI

Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Christopher J L Murray, +2272 more
- 17 Oct 2020 - 
TL;DR: The largest declines in risk exposure from 2010 to 2019 were among a set of risks that are strongly linked to social and economic development, including household air pollution; unsafe water, sanitation, and handwashing; and child growth failure.
Journal ArticleDOI

Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Simon I. Hay, +803 more
- 16 Sep 2017 - 
TL;DR: At a global level, DALYs and HALE continue to show improvements and the importance of continued health interventions, which has changed in most locations in pace with the gross domestic product per person, education, and family planning.
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Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

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Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017

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