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Open AccessJournal ArticleDOI

Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Theo Vos, +2419 more
- 17 Oct 2020 - 
- Vol. 396, Iss: 10258, pp 1204-1222
TLDR
Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates, and there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries.
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This article is published in The Lancet.The article was published on 2020-10-17 and is currently open access. It has received 5802 citations till now. The article focuses on the topics: Disease burden & Years of potential life lost.

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Citations
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Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases

TL;DR: The MetaBrain this article meta-analyses performed in multiple brain region-and ancestry-specific datasets (n ≤ 2,759) were conducted to identify therapeutic targets from genome-wide association studies (GWAS) requires insights into downstream functional consequences.
Journal ArticleDOI

The global burden of nasopharyngeal carcinoma from 2009 to 2019: an observational study based on the Global Burden of Disease Study 2019

TL;DR: The authors in this paper found that smoking, occupational exposure to formaldehyde, and alcohol use were the main risk factors for nasopharyngeal carcinoma (NPC) related mortality.
Journal ArticleDOI

Changing Epidemiology of Respiratory Tract Infection during COVID-19 Pandemic

TL;DR: NPIs could be effective in preventing respiratory tract infection and changing the microbiologic distribution of respiratory pathogens; however, epidemiological surveillance should be continued to establish updated information, antimicrobial stewardship programs for appropriate use of antibiotic, and infection control prevention interventions to prevent the spread of MDROs during the COVID-19 pandemic.
Journal ArticleDOI

Discogenic Low Back Pain: Anatomy, Pathophysiology and Treatments of Intervertebral Disc Degeneration

TL;DR: In this article , the authors focus on the anatomy of the intervertebral disc (IVD) and the pathophysiology of disc degeneration that contribute to the development of discogenic pain.
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Oxidative Stress Links Aging-Associated Cardiovascular Diseases and Prostatic Diseases.

TL;DR: In this paper, the role of oxidative stress in the development of cardiovascular and prostatic diseases is summarized and the main shared pathways underlying these diseases are also discussed in order to provide potential prevention and treatment targets.
References
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Journal ArticleDOI

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Theo Vos, +778 more
- 16 Sep 2017 - 
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195 countries and territories from 1990 to 2016.
Journal ArticleDOI

Global, regional, and national incidence, prevalence, andyears lived with disability for 354 diseases and injuries for195 countries and territories, 1990–2017: a systematicanalysis for the Global Burden of Disease Study 2017

TL;DR: All-cause age-standardised YLD rates decreased by 3·9% from 1990 to 2017; however, the all-age YLD rate increased by 7·2% while the total sum of global YLDs increased from 562 million (421–723) to 853 million (642–1100).
Journal ArticleDOI

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017

Gregory A. Roth, +1028 more
- 10 Nov 2018 - 
TL;DR: Non-communicable diseases comprised the greatest fraction of deaths, contributing to 73·4% (95% uncertainty interval [UI] 72·5–74·1) of total deaths in 2017, while communicable, maternal, neonatal, and nutritional causes accounted for 18·6% (17·9–19·6), and injuries 8·0% (7·7–8·2).
Journal ArticleDOI

Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Christopher J L Murray, +2272 more
- 17 Oct 2020 - 
TL;DR: The largest declines in risk exposure from 2010 to 2019 were among a set of risks that are strongly linked to social and economic development, including household air pollution; unsafe water, sanitation, and handwashing; and child growth failure.
Journal ArticleDOI

Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Simon I. Hay, +803 more
- 16 Sep 2017 - 
TL;DR: At a global level, DALYs and HALE continue to show improvements and the importance of continued health interventions, which has changed in most locations in pace with the gross domestic product per person, education, and family planning.
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Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

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Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017

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