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Open AccessJournal ArticleDOI

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Theo Vos, +778 more
- 16 Sep 2017 - 
- Vol. 390, Iss: 10100, pp 1211-1259
TLDR
The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195 countries and territories from 1990 to 2016.
About: 
This article is published in The Lancet.The article was published on 2017-09-16 and is currently open access. It has received 10401 citations till now. The article focuses on the topics: Mortality rate.

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AMPK, Mitochondrial Function, and Cardiovascular Disease.

Shengnan Wu, +1 more
- 15 Jul 2020 - 
TL;DR: This review begins with the description of AMPK structure and regulation, and then focuses on the recent advances toward understanding how mitochondrial dysfunction controls AMPK and how AMPK, as a central mediator of the cellular response to energetic stress, maintains mitochondrial homeostasis.
Journal ArticleDOI

Association of glucose-lowering medications with cardiovascular outcomes: an umbrella review and evidence map

Jianhong Zhu, +10 more
- 01 Mar 2020 - 
TL;DR: The association between glucose-lowering medications and a broad range of cardiovascular outcomes was examined, and the strength of evidence for these associations was assessed.
Journal ArticleDOI

Local Arctic Air Pollution: A Neglected but Serious Problem

Julia Schmale, +7 more
- 01 Oct 2018 - 
TL;DR: In this paper, the authors focus on estimating the air pollution in the Arctic caused by local emission sources, and present-day inventories show a large spread in the amount and location of emissions representing a significant source of uncertainty in model predictions that often deviate significantly from observations.
Journal ArticleDOI

Medication-overuse headache: a widely recognized entity amidst ongoing debate.

Nicolas Vandenbussche, +10 more
- 13 Jul 2018 - 
TL;DR: The historical background of medication- overuse headache, its epidemiology, phenomenology, pathophysiology and treatment options are explored, and relevant unanswered questions are explored and the current debates in medication-overuse headache are summarized.
Journal ArticleDOI

A dual-action peptide-containing hydrogel targets wound infection and inflammation

Manoj Puthia, +7 more
- 01 Jan 2020 - 
TL;DR: The development of a hydrogel formulation that was functionalized with TCP-25 to target bacteria and associated PAMP-induced inflammation and the results suggest that this dual-action anti-inflammatory and antibacterial peptide-functionalized hydrogels is a promising approach for wound healing.
References
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Reference EntryDOI

Diagnostic and Statistical Manual of Mental Disorders

Janet B. W. Williams
Journal ArticleDOI

European Guidelines on Cardiovascular Disease Prevention in Clinical Practice (Version 2012)

Massimo Piepoli, +25 more
- 01 Jul 2012 - 
TL;DR: In this paper, a randomized clinical trial was conducted to evaluate the effect of preterax and Diamicron Modified Release Controlled Evaluation (MDE) on the risk of stroke.
Journal ArticleDOI

2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Neil J. Stone, +15 more
- 24 Jun 2014 - 
TL;DR: Preamble and Transition to ACC/AHA Guidelines to Reduce Cardiovascular Risk S2 The goals of the …
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Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013

Mohammad H. Forouzanfar, +736 more
- 05 Dec 2015 - 
TL;DR: The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) as discussed by the authors provides a timely opportunity to update the comparative risk assessment with new data for exposure, relative risks, and evidence on the appropriate counterfactual risk distribution.
Journal ArticleDOI

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017

Gregory A. Roth, +1028 more
- 10 Nov 2018 - 
TL;DR: Non-communicable diseases comprised the greatest fraction of deaths, contributing to 73·4% (95% uncertainty interval [UI] 72·5–74·1) of total deaths in 2017, while communicable, maternal, neonatal, and nutritional causes accounted for 18·6% (17·9–19·6), and injuries 8·0% (7·7–8·2).
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