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Open AccessJournal ArticleDOI

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Theo Vos, +778 more
- 16 Sep 2017 - 
- Vol. 390, Iss: 10100, pp 1211-1259
TLDR
The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195 countries and territories from 1990 to 2016.
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This article is published in The Lancet.The article was published on 2017-09-16 and is currently open access. It has received 10401 citations till now. The article focuses on the topics: Mortality rate.

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Citations
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Targeted CGRP Small Molecule Antagonists for Acute Migraine Therapy.

TL;DR: Clinical trial data suggests that intermittent use of CGRP antagonists in intermittent use remains a viable and safe alternative, with 2 molecules remaining in clinical development (ubrogepant and rimegepants).
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Restoration of Autophagic Flux Rescues Oxidative Damage and Mitochondrial Dysfunction to Protect against Intervertebral Disc Degeneration.

TL;DR: In this paper, the effect of curcumin (CUR) on intervertebral disc degeneration (IDD) was investigated in vitro and in vivo, and it was shown that CUR alleviated TBHP-induced interruption of autophagosome-lysosome fusion and impairment of lysosomal function and thus contributed to the restoration of blocked autophagic clearance.
Journal ArticleDOI

Trends in incidence and prevalence of osteoarthritis in the United Kingdom: findings from the Clinical Practice Research Datalink (CPRD)

TL;DR: In the UK approximately one in 10 adults have symptomatic clinically diagnosed OA, the knee being the commonest, while prevalence has increased and become static after 2008, incidence is slowly declining.
References
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Journal ArticleDOI

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013

Mohammad H. Forouzanfar, +736 more
- 05 Dec 2015 - 
TL;DR: The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) as discussed by the authors provides a timely opportunity to update the comparative risk assessment with new data for exposure, relative risks, and evidence on the appropriate counterfactual risk distribution.
Journal ArticleDOI

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017

Gregory A. Roth, +1028 more
- 10 Nov 2018 - 
TL;DR: Non-communicable diseases comprised the greatest fraction of deaths, contributing to 73·4% (95% uncertainty interval [UI] 72·5–74·1) of total deaths in 2017, while communicable, maternal, neonatal, and nutritional causes accounted for 18·6% (17·9–19·6), and injuries 8·0% (7·7–8·2).
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Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

Theo Vos, +699 more
- 08 Oct 2016 - 

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017

Gregory A. Roth, +1028 more
- 10 Nov 2018 -