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Yao He

Researcher at Peking University

Publications -  20
Citations -  3509

Yao He is an academic researcher from Peking University. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 11, co-authored 13 publications receiving 1574 citations. Previous affiliations of Yao He include Tsinghua University.

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Pan-cancer analysis of whole genomes

Peter J. Campbell, +1332 more
- 06 Feb 2020 - 
TL;DR: The flagship paper of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium describes the generation of the integrative analyses of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types, the structures for international data sharing and standardized analyses, and the main scientific findings from across the consortium studies.
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Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer.

TL;DR: This comprehensive analysis of key myeloid subsets in human and mouse identifies critical cellular interactions regulating tumor immunity and defines mechanisms underlying myeloids-targeted immunotherapies currently undergoing clinical testing.
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Genomic basis for RNA alterations in cancer

TL;DR: The most comprehensive catalogue of cancer-associated gene alterations to date, obtained by characterizing tumour transcriptomes from 1,188 donors of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Gome Atlas (TCGA) was presented in this article.
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Direct Comparative Analyses of 10X Genomics Chromium and Smart-seq2.

TL;DR: In this article, the authors compared the performance of droplet-based 10X Genomics Chromium (10X) and plate-based Smart-seq2 full-length methods.